ANGIOGENIC AND ANGIOSTATIC CHEMOKINES LEVEL IN NORMAL SYNOVIAL FLUID

Abstract

Chemokines are believed to play an important role in immunopathogenesis of different joint diseases. One of important problems in studies of synovial fluid is determination of normal level of chemokines from control patients. In our study we determined concentrations of number of chemokines in relatively normal synovial fluid from subjects with background traumatic joint injury without systemic or local inflammation at the moment of study. Results for several CC- and CXC-chemokines are shown for the first time. Therefore, our data can be further used in analysis of synovial fluid chemokine profile in studies of joint disease of different etiology