Liver elastography in children practice

Abstract

We anylised results of elastography of 77 patients with chronic liver diffus lesions including: viruses hepatitis B, C, D – 50, autoimmune – 16, metabolic disease – 6, neonatal hepatities – 5 persons. Fibrosis stage was assessed on METAVIR scail. For patients with viruses hepatitis B, C with an averege duration of disease 9,8±0,7 years, a minimum fibrosis stage (F0-1) and low cytolytic activity were indicated. Patients with viruses hepatitis D were characterised by F2 fibrosis stage at the level of hyperenzemia to 4-5 rate, and history of the disease – 10,3±1,8 years. Patients with metabolic liver damage showed signs of modarate fibrosis at 10,3±1,8 years. Heavy fibrosis was marked in autoimmune hepatitis with duration of disease 5 years and indicators of ALT to 3 rate. Neonatal hepatities were characterised by the highest level of cytolysis and by development of fibrosis in 80% of cases with 0,9+0,3 year history of the disease