Region and volume dependencies in spectral linewidth assessed by 1H 2D chemical shift imaging in the monkey brain at 7T

Abstract

High magnetic fields increase the sensitivity and spectral dispersion in MR spectroscopy. In contrast, spectral peaks are broadened in vivo at higher field strength due to stronger susceptibility-induced effects. Strategies to minimize the spectral linewidth are therefore of critical importance. In the present study, 1H 2D chemical shift imaging (CSI) at short echo time was performed in the macaque monkey brain at 7 T. Dependencies of spectral linewidth on the CSI voxel size were determined by data reconstruction at different spatial resolution. An overall linewidth narrowing at increased spatial resolution is shown and regional differences are demonstrated

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