Indirect evidence suggests that arm cycling, along with other types of human locomotion, is partially controlled by specialized groups of spinal interneurones known as central pattern generators (CPGs). Further, it is known that the brain is directly involved in the control of arm cycling, however its specific roles are not well understood. The overwhelming majority of information regarding the brain’s role in control of human motor output has come from isometric or tonic contraction, however it has been shown that the cortical input on locomotion differs from that of isometric contraction. It has been shown that inhibitory connections exist between homologous areas of the motor cortices (IHI), which have a direct influence on the motor control of isometric contraction. To date, no study has examined the existence of IHI during locomotion. Therefore, the purpose of this study was to explore the potential influence of IHI during locomotion, using arm cycling as a locomotor model
