ADDITIONAL ALKALOIDS FROM LAURELIA PHILIPPIANA AND L. NOVAE-ZELANDIAE

Abstract

Asimilobine. anonaine. noreorydine. nornantenine. (+)-reticuline and lhe new alkaloid. 4-hydroxyanonaine. were isolaled from Laur~litJpllilippialla bark. The biogenelically relaled obovanine. oxopulerine and (-)-romneine. not known as a natural produel. were oblained from lhe bark of L. lIol'a~-ulalldia~. The oeeurrenee of (R)-norlaudanosoline-derived alkaloids in L lIova~·ulallditJ~ is a distinctive feature of this tree. Neither L. not'at-ulalldiat nor L. pllilippiana aeeumulate dimeric benzylisoquinoline alkaloids lo any appreciable extenl in lhe lrunk bark. dilfering in this respeel from L. umptn·irtlls. the only other Laurtlia speeies.This work was supoported by DICYT and the Organization of American States