Objective Determining dental caries’ experience, prevalence and severity in students applying for degree courses at San Luis Potosi University (UASLP). Material and Methods A cross-sectional study was carried out involving adolescents and young adults (16 to 25 years old) applying for undergraduate courses at UASLP (~10 %, n=1 027). Two standardized examiners undertook dental examinations; DMFT index, prevalence (DMFT and gt;0), severity (DMFT and gt;3 and DMFT and gt;6) and significant caries index (SiC) were calculated. STATA 9.0 non-parametric tests were used for statistical analysis.Results Mean age was 18.20±1.65; 48.0% were female. The DMFT index was 4.04±3.90 and caries prevalence was 74.4%. Regarding caries’ severity, 48.8% had MDFT and gt;3 and 24% DMFT and gt;6. The SiC index was 8.64. Females had higher caries experience than males (4.32±4.01 cf 3.78±3.78; p0.05). Age was associated with both experience (