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Electrocatalytic oxidation and selective voltammetric detection of methyldopa in the presence of hydrochlorothiazide in real samples
Authors
B. Aflatoonian
M.R. Aflatoonian
+6 more
M. Bamorovat
H. Beitollahi
Z. Dourandish
G.N. Fariba
I.S. Shoaie
S. Tajik
Publication date
1 January 2020
Publisher
Abstract
The combination of methyldopa and hydrocholorothiazide are used to treat high blood pressure. The present research dealt with the synthesis and utilization of the hexagonal-shaped of ZnO nanoparticles (NPs) to develop a new, sensitive, and exclusive electrochemical sensor for detection of methyldopa. Thus, we did our examination on the methyldopa detection via cyclic voltammetry (CV) method, differential pulse voltammetry (DPV) technique, and chronoamperometry (CH) at molybdenum (VI) complex-ionic liquid�ZnO NP modified carbon paste electrode (MCILZNMCPE) in 0.1 M PBS (pH of 7.0) solution. The use of DPV showed linear dependence of methyldopa peak current at pH of 7.0 solution on their concentration ranging between 0.05 and 300.0 µM. Then, limit of detection (LOD) has been determined to be 20.0 nM for methyldopa. Ultimately, the modified electrode has been utilized for detecting methyldopa in the presence of hydrochlorothiazide by DPV. © 2020 Elsevier B.V
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Simorgh Research Repository
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oai:eprints.kmu.ac.ir:32805
Last time updated on 16/05/2021
Simorgh Research Repository
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oai:eprints.kmu.ac.ir:37059
Last time updated on 16/05/2022
Simorgh Research Repository
See this paper in CORE
Go to the repository landing page
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oai:eprints.kmu.ac.ir:32778
Last time updated on 03/11/2020