Excel file describing highly significant SNPs (genome-wise FDR ≤ 5 %, FDR ≤ 1% and genome-wise Bonferroni ≤ 5 %) resulting from GWAS using single SNP regression mixed linear model for milk production (MILK), fat production (FAT), fat deviation (FATD), protein production (PROT) and protein deviation (PROTD). (XLS 518 kb

Flavio Schenkel (598286)

Mehdi Sargolzaei (551369)

Mohammed Abo-Ismail (3446567)

Natalie May (3446564)

Paul Stothard (5814)

Shadi Nayeri (3446561)

Stephen Miller (2182676)

Stephen Moore (233604)

Excel file describing previously identified production or fertility trait QTL that overlap with the SNPs identified in this study for calving to first service interval (CTFS). (XLS 30 kb

The Francis Crick Institute

Additional file 9: Table S4. of Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle

Excel file describing previously identified production or fertility trait QTL that overlap with the SNPs identified in this study for milk production (MILK), fat production (FAT), fat deviation (FATD), protein production (PROTD) and protein deviation (PROTD). (XLS 4775 kb

Additional file 4: Table S3. of Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle

Excel file describing highly significant SNPs (genome-wise FDR ≤ 5 %, FDR ≤ 1% and genome-wise Bonferroni ≤ 5 %) resulting from GWAS using single SNP regression mixed linear model for calving to first service interval (CTFS) and days open (DO). (XLS 40 kb

Additional file 8: Table S2. of Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle

Common significant SNPs (genome-wise 1Â % FDR) identified among all production related traits (MILK, FAT, PROT, FATD, PROTD) using single SNP regression mixed linear model on imputed BovineHD (777Â k) genotypes in Holstein cattle. (XLS 43 kb

Additional file 6: Table S7. of Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle

Excel file describing gene ontology biological process terms enriched among GWAS results for production traits; milk production (MILK), fat production (FAT), fat deviation (FATD), protein production (PROT) and protein deviation (PROTD). (XLS 803 kb

Additional file 5: Table S5. of Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle

Additional file 3: Table S1. of Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle

Common significant SNPs (genome-wise 1Â % FDR) identified among all fertility related traits (CTFS and DO) using single SNP regression mixed linear model on the imputed BovineHD (777Â k) genotypes in Holstein cattle. (XLS 34 kb

Additional file 7: Table S8. of Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle

Genome-wide association analysis and quantile-quantile (Q-Q) of P-values of SNPs from single SNP regression mixed linear model for milk production traits: Panels A-D: The –log10 of the P-value for association with SNPs is plotted. Chromosome number is shown on the horizontal axis. The traits included in this file are A. fat production (FAT); B. fat deviation (FATD); C. protein production (PROT); D. protein deviation (PROTD). The red line is the threshold for significant SNPs at 1 % FDR. The green line is the threshold for significant SNPs at 5 % FDR. Panels E-I: In the Q-Q plots the blue dots represent the –log10(P-values) to the expected distribution under the null hypothesis of no association. The traits are shown as E. milk production (MILK); F. fat production (FAT); G. fat deviation (FATD); H. protein production (PROT); I. protein deviation (PROTD). The red line denotes the expected pattern under the null hypothesis. Deviations between the red line and blue dots indicate how the test statistics of loci deviate from the null hypothesis. (PPTX 971 kb

Additional file 1: Figure S1. of Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle

https://figshare.com/articles/Additional_file_4_Table_S3_of_Genome-wide_association_for_milk_production_and_female_fertility_traits_in_Canadian_dairy_Holstein_cattle/4352165

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