research
Causes and Consequences of Thyroid Dysfunction throughout Life: a population-based and genetic approach
- Publication date
- 2 July 2014
- Publisher
- __Abstract__
Adequate thyroid hormone (TH) levels are essential for normal growth and differentiation,
for the regulation of energy metabolism, and for the physiological function of
virtually all human tissues. This is illustrated by the well-known effects of hypo- and
hyperthyroidism. In addition, more recent studies show that also minor variation in
serum TH levels, even within the normal range, can have important effects on clinical
endpoints, such as bone mineral density, atrial fibrillation, metabolic syndrome
(3) and cardiovascular mortality.