Al-Sabi, Mohammad Nafi Solaiman

Enemark, Heidi

Hansen, Mette Sif

Jensen, Tim Kåre

Larsen, Gitte

Heidi Larsen Enemark

Mette Sif Hansen

Tim Kåre Jensen

Gitte Larsen

Mohammad Nafi Solaiman Al-Sabi

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Veterinary Parasitology

An outbreak of bovine meningoencephalomyelitis with identification of Halicephalobus gingivalis

Halicephalobus gingivalis is an opportunistic parasite which is known to cause fatal meningoencephalomyelitis primarily in equines but sporadically also in humans. In April 2014, laboratory examination of the head of a young dairy calf, euthanized due to severe central nervous system symptoms, revealed the presence of granulomatous to necrotizing encephalitis and myriads of nematodes in the brain lesion. Morphologically the parasites were identified as H. gingivalis. The diagnosis was confirmed by molecular analysis of the large subunit (LSU) rRNA and the small subunit (SSU) rRNA genes, revealing genetic variations of 0.5–4.4% and 0.7–8.6%, respectively, between the H. gingivalis isolated from the Danish calf and published isolates, collected worldwide from free-living and parasitic stages of the nematode. Clinical symptoms and histological changes indicated infection with H. gingivalis from another three calves in the herd. This is the first scientific publication of H. gingivalis induced meningoencephalomyelitis in ruminants. As ante mortem diagnosis is a major challenge, the infection may easily remain undiagnosed in cattle

Online Research Database In Technology

An outbreak of bovine meningoencephalomyelitis with identification of Halicephalobusgingivalis - DTU Orbit (08/11/2017) An outbreak of bovine meningoencephalomyelitis with identification of Halicephalobus gingivalisHalicephalobus gingivalis is an opportunistic parasite which is known to cause fatal meningoencephalomyelitis primarily inequines but sporadically also in humans. In April 2014, laboratory examination of the head of a young dairy calf,euthanized due to severe central nervous system symptoms, revealed the presence of granulomatous to necrotizingencephalitis and myriads of nematodes in the brain lesion. Morphologically the parasites were identified as H. gingivalis.The diagnosis was confirmed by molecular analysis of the large subunit (LSU) rRNA and the small subunit (SSU) rRNAgenes, revealing genetic variations of 0.5–4.4% and 0.7–8.6%, respectively, between the H. gingivalis isolated from theDanish calf and published isolates, collected worldwide from free-living and parasitic stages of the nematode. Clinicalsymptoms and histological changes indicated infection with H. gingivalis from another three calves in the herd. This is thefirst scientific publication of H. gingivalis induced meningoencephalomyelitis in ruminants. As ante mortem diagnosis is amajor challenge, the infection may easily remain undiagnosed in cattle. General informationState: PublishedOrganisations: National Veterinary Institute, Section for Bacteriology, Pathology and ParasitologyAuthors: Enemark, H. (Intern), Hansen, M. S. (Intern), Jensen, T. K. (Intern), Larsen, G. (Intern), Al-Sabi, M. N. S. (Intern)Pages: 82-86Publication date: 2016Main Research Area: Technical/natural sciences Publication informationJournal: Veterinary ParasitologyVolume: 218ISSN (Print): 0304-4017Ratings: BFI (2017): BFI-level 1 Web of Science (2017): Indexed Yes BFI (2016): BFI-level 1 Scopus rating (2016): CiteScore 2.49 SJR 1.173 SNIP 1.228 Web of Science (2016): Indexed yes BFI (2015): BFI-level 1 Scopus rating (2015): SJR 1.21 SNIP 1.339 CiteScore 2.46 Web of Science (2015): Indexed yes BFI (2014): BFI-level 1 Scopus rating (2014): SJR 1.316 SNIP 1.421 CiteScore 2.53 Web of Science (2014): Indexed yes BFI (2013): BFI-level 1 Scopus rating (2013): SJR 1.251 SNIP 1.45 CiteScore 2.63 ISI indexed (2013): ISI indexed yes Web of Science (2013): Indexed yes BFI (2012): BFI-level 1 Scopus rating (2012): SJR 1.165 SNIP 1.454 CiteScore 2.6 ISI indexed (2012): ISI indexed yes Web of Science (2012): Indexed yes BFI (2011): BFI-level 1 Scopus rating (2011): SJR 1.228 SNIP 1.429 CiteScore 2.61 ISI indexed (2011): ISI indexed yes BFI (2010): BFI-level 1 Scopus rating (2010): SJR 1.244 SNIP 1.349 BFI (2009): BFI-level 1 Scopus rating (2009): SJR 1.131 SNIP 1.414 Web of Science (2009): Indexed yes BFI (2008): BFI-level 2 Scopus rating (2008): SJR 1.106 SNIP 1.218 Web of Science (2008): Indexed yes Scopus rating (2007): SJR 1.002 SNIP 1.437 Web of Science (2007): Indexed yes Scopus rating (2006): SJR 0.932 SNIP 1.444 Web of Science (2006): Indexed yes Scopus rating (2005): SJR 0.84 SNIP 1.444 Scopus rating (2004): SJR 0.878 SNIP 1.173 Web of Science (2004): Indexed yes Scopus rating (2003): SJR 0.808 SNIP 1.24 Web of Science (2003): Indexed yes Scopus rating (2002): SJR 0.899 SNIP 1.161 Web of Science (2002): Indexed yes Scopus rating (2001): SJR 0.615 SNIP 1.117 Scopus rating (2000): SJR 0.859 SNIP 1.2 Web of Science (2000): Indexed yes Scopus rating (1999): SJR 0.815 SNIP 1.063 Original language: EnglishDOIs: 10.1016/j.vetpar.2016.01.014 Source: FindItSource-ID: 2291559250Publication: Research - peer-review › Journal article – Annual report year: 2016 

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An outbreak of bovine meningoencephalomyelitis with identification of Halicephalobus gingivalis

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Online Research Database In Technology