Boisen, Anja

Burger, Robert

Creagh, Michael

Donolato, Marco

Fock, Jeppe

Hansen, Mikkel Fougt

Uddin, Rokon

We present a novel strategy for thrombin detection by combining a magnetic bead based agglutination assay and low-cost microfluidic disc. The detection method is based on an optomagnetic readout system implemented using a Blu-ray optical pickup unit (OPU) as main optoelectronic component. The assay, from sample to answer, is fully integrated on a microfluidic disc which embeds on-disc mixing ensuring full automation of the assay along with less sample-to-answer time compared to similar methods. Moreover, we compare the optomagnetic readout to the cluster size distribution determined using a commercial optical scanning imaging instrument

Online Research Database In Technology

Integration of agglutination assay for protein detection in microfluidic disc using Blu-rayoptical pickup unit and optical fluid scanning - DTU Orbit (08/11/2017) Integration of agglutination assay for protein detection in microfluidic disc using Blu-ray optical pickup unit and optical fluidscanningWe present a novel strategy for thrombin detection by combining a magnetic bead based agglutination assay and low-costmicrofluidic disc. The detection method is based on an optomagnetic readout system implemented using a Blu-ray opticalpickup unit (OPU) as main optoelectronic component. The assay, from sample to answer, is fully integrated on amicrofluidic disc which embeds on-disc mixing ensuring full automation of the assay along with less sample-to-answertime compared to similar methods. Moreover, we compare the optomagnetic readout to the cluster size distributiondetermined using a commercial optical scanning imaging instrument. General informationState: PublishedOrganisations: Department of Micro- and Nanotechnology, Nanoprobes, Magnetic SystemsAuthors: Uddin, R. (Intern), Burger, R. (Intern), Donolato, M. (Intern), Fock, J. (Intern), Creagh, M. (Intern), Hansen, M. F.(Intern), Boisen, A. (Intern)Number of pages: 3Pages: 1807-1809Publication date: 2015 Host publication informationTitle of host publication: Proceedings of MicroTAS 2015Main Research Area: Technical/natural sciencesConference: MicroTAS 2015, Gyeongju, Korea, Republic of, 25/10/2015 - 25/10/2015Agglutination assay, Aptamer, Magnetic beads, Centrifugal Microfluidics, Thrombin, Microfluidic discElectronic versions: Integration_of_agglutination_assay.pdf Source: PublicationPreSubmissionSource-ID: 118520731Publication: Research - peer-review › Article in proceedings – Annual report year: 2015 

Integration of agglutination assay for protein detection in microfluidic disc using Blu-ray optical pickup unit and optical fluid scanning

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Integration of agglutination assay for protein detection in microfluidic disc using Blu-ray optical pickup unit and optical fluid scanning

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