NASASP-7011 (164) AEROSPACE MEDICINE AND BIOLOGY CASE FILE COPY A CONTINUING BIBLIOGRAPHY WITH INDEXES (Supplement 164) FEBRUARY 1977 NATIONAL AERONAUTICS AND SPACE ADMINISTRATION https://ntrs.nasa.gov/search.jsp?R=19770012801 2020-03-22T11:34:12+00:00Z ACCESSION NUMBER RANGES Accession numbers cited in this Supplement fall within the following ranges: STAR (N-10000 Series) N77-10001—N77-11966 IAA (A-10000 Series) A77-10001—A77-12945 This bibliography was prepared by the NASA Scientific and Technical Information Facility operated for the National Aeronautics and Space Administration by Informatics Information Systems Company. NASASP-7011 (164) AEROSPACE MEDICINE AND BIOLOGY A CONTINUING BIBLIOGRAPHY WITH INDEXES (Supplement 164) A selection of annotated references to unclas- sified reports and journal articles that were introduced into the NASA scientific and tech- nical information system and announced in January 1977 in • Scientific and Technical Aerospace Reports (STAR) • International Aerospace Abstracts (IAA) Scientific and Technical Information Office FEBRUARY 1977 NATIONAL AERONAUTICS AND SPACE ADMINISTRATION Washington, D.C. NASA SP-7011 and its supplements are available from the National Technical Information Service (NTIS). Questions on the availability of the predecessor publications, Aerospace Medicine and Biology (Volumes I - XI) should be directed to NTIS. This Supplement is available from the National Technical Information Service (NTIS), Springfield, Virginia 22161, at the price code E02 ($4 75 domestic, $9 50 foreign) INTRODUCTION This Supplement to Aerospace Medicine and Biology (NASA SP-7011) lists 275 reports, articles and other documents announced during January 1977 in Scientific and Technical Aerospace Reports (STAR) or in International Aerospace Abstracts (IAA) The first issue of the bibliography was published in July 1964; since that time, monthly supplements have been issued. In its subject coverage, Aerospace Medicine and Biology concentrates on the biological, physiological, psychological, and environmental effects to which man is subjected during and following simulated or actual flight in the earth's atmosphere or in interplanetary space References describing similar effects of biological organisms of lower order are also included. Such related topics as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, exobiology, and personnel factors receive appropriate attention In general, emphasis is placed on applied research, but references to fundamental studies and theoretical principles related to experimental development also qualify for inclusion. Each entry in the bibliography consists of a bibliographic citation accompanied in most cases by an abstract. The listing of the entries is arranged in two major sections: IAA Entries and STA R Entries, in that order The citations, and abstracts when available, are reproduced exactly as they appeared originally in IAA or STAR, including the original accession numbers from the respective announcement journals. This procedure, which saves time and money, accounts for the slight variation in citation appearances. Two indexes - subject and personal author -- are included An annual index will be prepared at the end of the calendar year covering all documents listed in the 1977 Supplements AVAILABILITY OF CITED PUBLICATIONS IAA ENTRIES (A77-10000 Series) All publications abstracted in this Section are available from the Technical Information Service. American Institute of Aeronautics and Astronautics. Inc (AIAA), as follows Paper copies are available at $5 00 per document up to a maximum of 20 pages The charge for each additional page is 25 cents Microfiche " are available at the rate of $1 50 per microfiche for documents identified by the § symbol following the accession number A number of publications, because of their special characteristics, are available only for reference in the AIAA Technical Information Service Library Minimum airmail postage to foreign countries is $1 00 Please refer to the accession number, eg, (A77-10052), when requesting publications STAR ENTRIES (N77-10000 Series) One or more sources from which a document announced in STAR is available to the public is ordinarily given on the last line of the citation The most commonly indicated sources and their acronyms or abbreviations are listed below If the publication is available from a source other than those listed, the publisher and his address will be displayed on the availability line or in combination with the corporate source line Avail NTIS Sold by the National Technical Information Service Prices for hard copy (HC) and microfiche (MF) are indicated by a price code followed by the letters HC or MF in the STAR citation Price codes are given in the tables on page vu of the current issue of STAR Microfiche111 is available regardless of age for those accessions followed by a # symbol Initially distributed microfiche under the NTIS SRIM (Selected Research m Microfiche) is available at greatly reduced unit prices For this service and for information concerning subscription to NASA printed reports, consult the NTIS Subscription Unit NOTE ON ORDERING DOCUMENTS When ordering NASA publications (those followed by the * symbol), use the N accession number NASA patent applications (only the specifications are offered) should be ordered by the US-Patent-Appl-SN number Non-NASA publications (no astenck) should be ordered by the AD, PB, or other report number shown on the last line of the citation, not by the N accession number It is also advisable to cite the title and other bibliographic identification Avail SOD (or GPO) Sold by the Superintendent of Documents, U S Government Printing Office, in hard copy The current price and order number are given following the availability line (NTIS will fill microfiche requests, at the standard $300 price, for those documents identified by a # symbol) Avail NASA Public Document Rooms Documents so indicated may be examined at or purchased from the National Aeronautics and Space Administration, Public Documents Room (Room 126), 600 Independence Ave , SW, Washington, DC 20546, or public document rooms located at each of the NASA research centers, the NASA Space Technology Laboratories, and the NASA Pasadena Office at the Jet Propulsion Laboratory (1) A microfiche is a transparent sheet of film 105 by 148 mm in size, containing as many as 60 to 98 pages of information reduced to micro images (not to exceed 26 1 reduction) Avail ERDA Depository Libraries Organizations in U S cities and abroad that maintain collections of Energy Research and Development Administration reports, usually in microfiche form, are listed in Nuclear Science Abstracts Services available from the ERDA and its depositories are described in a booklet. Science Information Available from the Energy Research and Development Administration (TID-4550), which may be obtained without charge from the ERDA Technical Information Center Avail Umv Microfilms Documents so indicated are dissertations selected from Dissertation Abstracts and are sold by University Microfilms as xerographic copy (HC) and microfilm All requests should cite the author and the Order Number as they appear in the citation Avail USGS Originals of many reports from the U S Geological Survey, which may contain color illustrations, or otherwise may not have the quality of illustrations preserved in the microfiche or facsimile reproduction, may be examined by the public at the libraries of the USGS field offices whose addresses are listed in this introduction The libraries may be queried concerning the availability of specific documents and the possible utilization of local copying services, such as color reproduction Avail HMSO Publications of Her Majesty's Stationery Office are sold in the U S by Pendragon House, Inc (PHI). Redwood City, California The U S price (including a service and mailing charge) is given, or a conversion table may be obtained from PHI Avail BLL (formerly NLL) British Library Lending Division, Boston Spa, Wetherby, Yorkshire, England Photocopies available from this organization at the price shown (If none is given, inquiry should be addressed to the BLL) Avail 2LDI Sold by the Zentralstelle fur Luftfahrtdokumentation und -Information, Munich, Federal Republic of Germany, at the price shown m deutschmarks (DM) Avail Issuing Activity, or Corporate Author, or no indication of availability Inquiries as to the availability of these documents should be addressed to the organization shown in the citation as the corporate author of the document Avail U S Patent Office Sold by Commissioner of Patents, U S Patent Office, at the standard price of 50 cents each, postage free Other availabilities If the publication is available from a source other than the above, the publisher and his address will be displayed entirely on the availability line or in combi - nation with the corporate author line SUBSCRIPTION AVAILABILITY This publication is available on subscription from the National Technical Information Service (NTIS) The annual subscription rate for the monthly supplements, excluding the annual cumula- tive index, is $45 OO domestic, $75 00 foreign All questions relating to the subscriptions should be referred to NTIS ADDRESSES OF ORGANIZATIONS American Institute of Aeronautics and Astronautics Technical Information Service 750 Third Ave New York. NY 10017 British Library Lending Division. Boston Spa. Wetherby. Yorkshire. England Commissioner of Patents U S Patent Office Washington. DC 20231 Pendragon House. Inc 899 Broadway Avenue Redwood City, California 94063 Superintendent of Documents U S Government Printing Office Washington. D C 20402 University Microfilms A Xerox Company 300 North Zeeb Road Ann Arbor, Michigan 48106 Energy Research and Development Administration Technical Information Center P O Box 62 Oak Ridge. Tennessee 37830 ESA-Space Documentation Service ESRIN Via Galileo Galilei 00044 Frascati (Rome) Italy Her Majesty's Stationery Office P O Box 569. S E 1 London, England University Microfilms. Ltd Tylers Green London, England U S Geological Survey 1033 General Services Administration Building Washington, D C 20242 U S Geological Survey 601 E Cedar Avenue Flagstaff. Arizona 86002 NASA Scientific and Technical Information _ Facility PO Box 8757 B W I Airport. Maryland 21240 National Aeronautics and Space Administration Scientific and Technical Information Office (KSI) Washington. D C 20546 National Technical Information Service 5285 Port Royal Road Springfield. Virginia 22161 U S Geological Survey 345 Middlefield Road Menlo Park. California 94025 U S Geological Survey Bldg 25, Denver Federal Center Denver. Colorado 80225 Zentralstelle fur Luftfahrtdoku- mentation und -Information 8 Munchen 86 Postfach 880 Federal Republic of Germany VI T A B L E OF CONTENTS Page IAA Entries (A77-10000) 1 STAR Entries (N77-10000) 25 Subject Index 1-1 Personal Author Index 1-31 T Y P I C A L C I T A T I O N A N D A B S T R A C T F R O M STAR NASA SPONSORED DOCUMENT NASA ACCESSION | NUMBER- TITLE AUTHOR. CONTRACT OR GRANT- REPORT NUMBER- N77-10799*# Joint Publications Research Service Arlington Va r*- ON THE POSSIBLE UNIQUENESS OF INTELLIGENT LIFE - 1 IN THE UNIVERSE f [-*• I S Shklovskry Washington NASA Oct 1-976 19 p Transl J into ENGLISH of Report PR-262 Academy of Sciences USSR Inst of Space Res Moscow 1976 p 1-30 |-* (NASA Order W-13183) S (NASA-TT-F-17247) Avail NTIS HC A02/MF A01 CSCL' 03 C The modem conception of an expanding universe rejects theories of cosmic wonders transformation of matter or superintendent cosmic factors as sources of intelligent life on earth Life emerged on earth and became intelligent as the result of an extremely rare combination of improbable circumstances The expansion of intelligent life in the universe will be ac- complished by the establishment of artificial biospheres orbiting the moon or stationed in galaxcies Communications between these space colonies will rely on computer technology and radio astronomy A H AVAILABLE ON MICROFICHE -CORPORATE SOURCE I—PUBLICATION DATE AVAILABILITY SOURCE . COSATI CODE T Y P I C A L C I T A T I O N A N D A B S T R A C T F R O M I A A NASA SPONSORED DOCUMENT AIAA ACCESSION NUMBER AUTHOR'S AFFILIATION- CONTRACT GRANTOR SPONSORSHIP. V / • A77-10058 * Effects of head-down tilt on fluid and elec trolyte balance L Volicer, R Jean Charles, and A V Chobanian • • (Boston University, Boston. Mass ) AvialionfSpace, and Environ~ mental Medicine, vol 47, Oct 1976^p 106&1068 26 refs Grants . No NGR-22 004 021, No NIH RR 533 The metabolic effects of 5 deg tilt were studied in eight normal individuals Exposure to tilt for 24 hr increased sodium excretion and decreased plasma volume Plasma rerun activity and plasma atdosterone levels were not significantly different from supine values during the first 6 hr of tilting, but were increased significantly at the end of the 24 hr tilt period Creatimne clearance and potassium balance were not affected by the tilt These findings indicate that head-down tilt induces a sodium diuresis and stimulation of the renin angiotensm-aldosterone system (Author) TITLE -AUTHORS • TITLE OF PERIODICAL .PUBLICATION DATE VII AEROSPACE MEDICINE AND BIOLOGY A Continuing Bibliography (Suppl. 164) FEBRUARY 1977 IAA ENTRIES A77-10051 Readability of approach charts as a function of visual acuity, luminance, and printing format K W Welsh, J A Vaughan, and P G Rasmussen (FAA, Aeronautical Center, Okla- homa City, Okla ) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 10271031 10refs This study determined the ability of 12 presbyopic subjects to read numerals from aeronautical approach procedure charts The readability of chart numerals was determined for 15 size and contrast combinations as a function of near visual acuity (equivalent 20/20, 20/40, and 20/60) and chart brightness (100 and 1 0 ft L) Test subjects were evaluated at the normal near-visual acuity level (20/20) and the minimal near-visual-acuity levels (20/40 for Classes I and II and 20/60 for Class III) as specified in the FAA's Guide for Aviation Medical Examiners The results indicated that subjects with 20/20 near visual acuity could read all chart numerals under bright and dim luminance conditions Subjects with 20/40 and 20/60 levels of near visual acuity experienced reading difficulty under bright conditions and increased difficulty under dim luminance (Author) A77-10052 Pulmonary gas exchange in acute mountain sickness J R Sutton, A C Bryan, G W Gray, E S Morton, A S Rebuck, W Woodley, I D Renme, and C S Houston (McMaster University, Hamilton, Ontario, North America, Arctic Institute, Yukon, Defence and Civil Institute of Environmental Medicine, Toronto, Canada, Vermount, University, Burlington, Vt) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1032-1037 31 refs Grant No NIH-HL-14102-05 The seventy of acute mountain sickness (AMS) was investigated in healthy volunteers, airlifted to high altitude (5,360 m) Blood gases were measured at 2,990 m and 5,360 m Symptoms of AMS were found in all subjects, but ranged from malaise to vomiting with intractable headache The clinical severity of AMS was directly related to the arterial P(C02) and inversely to pH, but unrelated to the P(O2) on arrival at high altitude However, P(02) fell and was lowest 48 hr after arrival at high altitude in those subjects with the most severe AMS These were the only subjects to show an increase in the alveolar-arterial P(02) difference and in the venous admixture ratio during the first 48 hr These abnormalities in gas exchange, which developed in the subjects with the most marked cerebral symptoms, suggest that the manifestations of cerebral and pul- monary dysfunction at altitude develop simultaneously, a finding that suggests coexisting cerebral and pulmonary edema (Author) A77-10053 Measurement of change in plasma volume during heat exposure and exercise M H Harrison and R J Edwards (RAF, Institute of Aviation Medicine, Farnborough, Hants, England) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1038-1045 17 refs The application of radio-iodmated human serum albumin (RISA) to the measurement of a continuously changing plasma volume, such as that occurring during heat exposure and exercise, has been considered in terms of the exchange dynamics of albumin between the intravascular and extravascular compartments In six male subjects resting supine for 2 hr in a hot environment, or exercising for 50 mm in a thermoneutral or hot environment, there was no statistically significant alteration in the rate of protein efflux from the intravascular space However, following exercise, protein was added to the circulation at a greater rate than it was lost through the capillary walls A technique for calculating plasma volume from a single measurement of plasma RISA activity is described This may be used in conjunction with measurements of changes in hemoglobin concentration for determining plasma volume in situations where alterations in protein exchange dynamics do occur (Author) A77-10054 Cardiac output during human sleep J C Miller and S M Horvath (California, University, Santa Barbara, Calif ) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1046-1051 Grant No AF-AFOSR-73-2455 Impedance cardiogram and sleep EEC were recorded from four male and four female subjects, aged 21 to 22 years, during one night in the laboratory following one adaptation night Cardiac output fell approximately 26% during the night as a consequence of diminished stroke volume, the lowest values of both occurring during the latter portion of the night, dominated by SREM (rapid-eye-movement stage) Intracycle comparisons between SREM and SWS (slow-wave sleep) or between eye movement burst and non-burst SREM shows no significant differences in stroke volume or cardiac output Pre-ejection period and systolic ejection period were measured and discussed The noncomcidence of the nadir of metabolic activity, expressed as cardiac output, and the apex of slow-wave sleep activity supported the concept of slow-rate sleep as a period of physiological restoration (Author) A77-10055 Intracerebral oxygen and carbon dioxide ten- sions in the rhesus monkey J A Kennealy, F P Witte, R D Brown, J S Kirkland, and A A Karl (USAF, Aerospace Medical Research Laboratory, Wright-Patterson AFB, Systems Research Laboratories, Inc , Dayton, Ohio) Aviation, Space, and Environ- mental Medicine, vol 47, Oct 1976, p 1052-1055 18 refs Five rhesus monkeys (M mulatta) were prepared by surgical placement of a stainless steel implant in the parietal area of the skull The implant was designed to firmly hold a Teflon-coated membrane of a medical mass spectrometer in an mtracerebral position Animals were consecutively exposed to varying ambient oxygen concentra- tions from 11% to 21% Intracerebral P(02) and P(C02) and arterial P(02) were all simultaneously recorded for computer analysis Results indicate an almost linear relationship between cerebral P(02) and ambient P(02) as well as between cerebral P(02) and arterial P(02) With an ambient oxygen concentration of 21%, the cerebral P(02) and P(C02) were 13 5 plus or minus 3 5 mm Hg and 50 4 plus or minus 7 9 mm Hg, respectively With an ambient oxygen concentration of 10 7%, these values decreased to 2 5 plus or minus 2 7 mm Hg and 38 0 plus or minus 5 6 mm Hg (Author) A77-10056 A77-10056 * Medical experiment M-171 - Results from the second manned Skylab mission J A Rummel, E L Michel, C F Sawm, and M C Buderer (NASA, Johnson Space Center, Technol- ogy, Inc , Life Sciences Div , Houston, Tex ) Aviation, Space, and Environmental Medicine, vol 47,Oct 1976, p 1056-1060 6 refs Preflight, inflight, and postfhght exercise response tests were conducted on the astronauts of the second Skylab mission as part of an evaluation of physiological adaptation to long-term weightless- ness The flight phase of this mission was 59 days in duration An exercise protocol was designed around a bicycle ergometer which was used to apply work loads approximating 25, 50, and 75% of each crewman's measured maximum aerobic capacity Respiratory gas exchange, heart rate, and blood pressure were measured during all tests, cardiac output was measured.at selected times during preflight and postfhght tests Data obtained both at rest and during exercise in flight showed no consistent changes which would indicate a degraded physical work capacity In fact, heart rate during exercise actually decreased for all crewmen in flight This response indicated improved physical fitness in flight relative to preflight The postfhght period of readaptation to 1 G was characterized by a marked tachycardia, during which time stroke volume was decreased This response returned to normal within 5-day postfhght (Author) A77-10057 Free ammo acids in human blood plasma during space flights A S Ushakov and T F Vlasova (Ministry of Health of USSR, Institute of Biomedical Problems, Moscow, USSR) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1061-1064 14refs The present investigation presents results of studying free ammo acids of peripheral plasma in cosmonauts who made space flights of different duration onboard the spacecraft Soyuz-12, Soyuz 16 and the orbital station Salyut-4 The study showed changes in the content of free ammo acids which varied for different ammo acids Most pronounced changes were found in the content of glutamic and aspartic acids, sulfur-containing ammo acids, and argmine (Author) A77-10058* Effects of head-down tilt on fluid and elec- trolyte balance L Volicer, R Jean-Charles, and A V Chobanian (Boston University, Boston, Mass) Aviation, Space, and Environ- mental Medicine, vol 47, Oct 1976, p 1065-1068 26 refs Grants No NGR-22-004-021,No NIH-RR-533 The metabolic effects of -5 deg tilt were studied in eight normal individuals Exposure to tilt for 24 hr increased sodium excretion and decreased plasma volume Plasma renin activity and plasma aldosterone levels were not significantly different from supine values during the first 6 hr of tilting, but were increased significantly at the end of the 24-hr tilt period Creatmine clearance and potassium balance were not affected by the tilt These-findings indicate that head-down tilt induces a sodium diuresis and stimulation of the renin angiotensm aldosterone system (Author) A77-10059 Increased 2,3-diphosphoglycerate during normocapnic hypobanc hypoxia A Cymerman, J T Maher, J C Denniston (U S Army, Research Institute of Environmental Medicine, Natick, Mass ), J T Reeves, R F Grover (U S Army, Research Institute of Environmental Medicine, Natick, Mass, Colorado, University, Denver, Colo ), and J C Cruz Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1069-1072 15 refs The effect of 96 hr of exposure to hypobanc hypoxia with and without 3 8% C02 supplementation was studied in two groups of subjects Five subjects (C02) were exposed to 440-465 mm Hg barometric pressure (4000-4400 m), and 4 subjects (no-C02) were exposed to 455-492 mm Hg (3500-4100 m) in order to produce similar levels of resting end-tidal P(02) After 24 hr, 2,3-DPG (diphosphoglycerate) levels of both groups significantly increased and remained elevated The CO2 group had higher levels than the no-C02 group after 48 and 72 hr Concurrent measurements of P(50) showed similar changes over the same time course Mean corpuscular hemoglobin concentrations remained normal for 48 hr and then decreased in both groups, the C02 group showing the larger decrease It is concluded that altitude exposure may produce an increase in 2,3-DPG without the presence of respiratory alkalosis previously thought necessary (Author) A77-10060 Responses of the autonomic nervous system during acclimatization to high altitude in man M S Malhotra, W Selvamurthy, S S Purkayastha, A K Mukherjee, L Mathew, and G L Dua (Defence Institute of Physiology and Allied Sciences, Delhi, India) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1076-1079 12 refs A study has been conducted on 20 sojourners aged 20-30 yr to evaluate responses of the autonomic nervous system during acclima- tization to high altitude The responses measured consisted of heart rate (HR), blood pressure (BP), oral temperature (Tor), mean skin temperature (Tsk), cold pressor response (CPR), orthostatic toler- ance to tilt, and urinary catecholammes The subjects were tested initially at an altitude of 260 m and then on acute induction to an altitude of 3500 m periodically for 3 weeks For comparison, the same responses were studied on acclimatized lowlanders and high- altitude natives The studies showed a rise in HR, BP, Tor, and urinary catecholammes, and a fall in Tsk, CPR, and orthostatic tolerance immediately on arrival at HA, indicating a relative hyperactivity of the sympathetic system After a stay of 1 week, there was a gradual recovery in all the responses, though sympathetic hyperactivity was still maintained throughout the 3 weeks of stay It is concluded that in lowlanders it takes more than a year of stay at altitude for complete recovery of autonomic balance (Author) A77-10061 Effect of penetrating radiation on skeletal muscles of rats in weightlessness N V Petrova and V V Portugalov (Ministry of Health of USSR, Institute of Biomedical Problems, Moscow, USSR) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1080-1082 12 refs The isoenzyme composition of lactate dehydrogenase of soleus and plantaris muscles of rats flown for 20 5 days aboard the biosatellite Cosmos-690 and irradiated with a dose of 800 rad was investigated The muscles exposed to weightlessness per se and weightlessness combined with radiation showed similar changes in their carbohydrate metabolism On return to 1 G, readaptation of irradiated rats developed less rapidly than of animals exposed to weightlessness alone . (Author) A77-10062 Antiorthostatic hypokmesia as a method of weightlessness simulation L I Kakurm, V I Lobachik, V M Mikhailov, and lu A Senkevich (Ministry of Health of USSR, Institute of Biomedical Problems, Moscow, USSR) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1083-1086 11 refs Physiological effects observed in 8 test subjects during a 5-day bedrest experiment m the head-down position (0, -4, -8, -12 deg) were studied It was shown that the antiorthostatic hypokmesia at -12 deg could reproduce physiological responses shown by space crewmembers more closely than recumbent bedrest The observa- tions help simulate an acute stage of human adaptation to the weightless state and to assess the part played by gravity-induced blood redistribution m the development of physiological changes (Author) A77-10063 Psychologic and psychophysiologic response to 105 days of social isolation D A Rockwell, M G Hodgson, J R Beljan, and C M Wmget (California, University, Davis, Calif) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1087-1093 38 refs The responses of nine subjects to 105 days of social isolation are reported The study reveals that crew selection plus ongoing support A77-10113 by psychiatric staff permits continued function in an exotic milieu Prediction of psychophysiologic symptoms was possible using paper and pencil tests Trait anxiety was altered by the isolation in a psychologically healthy direction Sudden time shifts of 8 hr led to an immediate significant increase in depression, aggression, and hostility, and are accompanied by marked increases m physical symptoms During the first free-running phase of the experiment, significant shifts were found on four psychological measures The shifts indicate that subjects became less trusting, more orderly, more routimzed, less energetic, and more depressed A reducer-augmenter scale predicted the number of psychophysiologic complaints re- ported by individual subjects while isolated A group interaction effect on circadian rhythms was isolated but needs further examina- tion (Author) A77-10064 * Prevention of experimental motion sickness by scopolamme absorbed through the skin A Graybiel, J Knepton, and J Shaw (U S Navy, Aerospace Medical Research Laboratory, Pensacola, Fla , Alza Research, Palo Alto, Calif ) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1096-1100 16 refs Navy Project MF52,524,005-7015, NASA Order T-5904-B A double-blind placebo-controlled study compared the efficacy of the antimotion sickness drug scopolamme when administered by oral or transdermal routes A secondary purpose was to extend our bioassay involving fixed-dose combinations of the homergic drugs promethazme and ephednne After receiving 12 apparently identical drug-placebo treatments, eight normal male students were exposed in a slow rotation room to stressful accelerations generated by their execution of 40 head movements out of the plane of the room's rotation at 1 rpm and at 1-rpm increments until either symptoms were experienced (just short of frank motion sickness) or the 27-rpm ceiling on the test was reached Efficacy of a drug was defined in terms of the placebo-range and categorized as beneficial, inconse- quential, or detrimental The only detrimental effect was with scopolamme given orally It is concluded that the advantages of the transdermal scopolamme, which include minimal side effects and prolonged effectiveness, deserve full exploitation (Author) A77-10065 Effects of rapid round trips against time displacement on adrenal cortical-medullary circadian rhythms. C Sekiguchi, T Kuta-Jima, Y Ueda (Jikei University, Tokyo, Japan), and 0 Yamaguchi (Japan Airlines Co , Ltd , Health Control Services, Tokyo, Japan) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1101-1106 22 refs Research supported by the Japan Civil Aviation Promotion Foundation The effects of rapid round trips against the displacement on circadian rhythms was investigated The study was carried out on three occasions using one volunteer healthy physician on east west trips (Tokyo-San Francisco-Tokyo) of short and prolonged stays The control study was performed on a north-south trip (Tokyo- Sydney-Tokyo) which had practically no time displacement The circadian rhythms of urinary 170HCS (hydrocorticosteroids), 17-KS, and noradrenahne excretions and plasma cortisol in short-stay trips were disrupted and not synchronized, however, the recovery was rapid with the Orcadian rhythms returning to normal within 1 and 2 days On the other hand, the circadian rhythms of these variables in the control study were not disrupted These results suggest that a short, overnight stay during the trip minimizes the ill effects due to time displacement (Author) A77-10066 Food sanitation and air safety A S R Peffers (British Airways, Medical Services, London, England) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1107, 1108 Ways in which poor hygiene or unsatisfactory disposal of food wastes may influence aircraft safety are identified A major food hazard is the sudden mcapacitation or collapse of a member of the operating crew with short incubation fulminating type of food poisoning due to bacterial toxins as seen in some staphylococcal infections Rats may gain access to aircraft by inefficient disposal of aircraft wastes and may damage electrical or control wire conduits Flies attracted by open food waste or garbage may contaminate food being prepared for use in aircraft or in airport restaurants where crew and passengers take refreshments. Fifteen key safety steps to be taken by aviation medicine workers and aircraft operators are mentioned S 0 A77-10067 Transportation in commercial aircraft of pas- sengers having contagious diseases M Perm (Compagme Nationale Air France, Paris, France) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1109-1113 22 refs Most airlines refuse to board passengers known or believed to have contagious diseases Such rigor can scarcely be justified by reference to either laws or regulations It introduces the risk of arbitrary, mistaken, or prejudiced conduct in areas in which international organizations recommend the greatest liberalization, and it can cause serious harm to certain patients Normal hygienic conditions aboard planes suppress the risks of contagion concerning most diseases transmitted by insects or through contact with the skin, with mucuous membranes, with the faeces, or with urine Airlines should continue to refuse to transport only those passengers having diseases which are characterized by vomiting or serious diarrhea or which are transmitted through the air if it is impossible by simple means to avoid the risk of contaminating other travellers and any members of the flight crew who might be receptive (Author) A77-10068 Exercise m an hypoxic environment as a screening test for ischaemic heart disease P K Khanna, S K Dham (Army Hospital, Delhi, India), and R S Hoon (Ministry of Defence, Armed Forces Medical Services, New Delhi, India) Aviation, Space, and Environmental Medicine, vol 47, Oct 1976, p 1174-1117 20 refs In 30 subjects with stabilized ischaemic heart disease (Group A) and 70 subjects with abnormal resting electrocardiogram (Group B), resting electrocardiograms - at ground level and at a simulated height of 4592 m (15000 ft) • after 40-mm exposures were recorded The double Master's two-step exercise test (DM) was performed at ground level as well as at simulated height (DMH) In the ischaemic group, exercise combined with hypoxia did not yield better results than exercise alone, but among the asymptomatic subjects, exercise in an hypoxic environment gave significantly better results than exercise alone (less than 0005) or hypoxia alone (p less then 001) Those with negative responses to the test have been employed on strenuous duties, including employment at high altitude for the last 3 years None of them have manifested any objective or subjective evidence of ischaemic heart disease DM exercise testing in an hypoxic environment is suggested to be a reliable method to assess subjects with abnormal electrocardiogram and evaluate their functional status (Author) A77-10113 Central nervous regulation of body tempera- ture during sleep S F Glotzbach and H C Heller (Stanford University, Stanford, Calif ) Science, vol 194, Oct 29, 1976, p 537-539 36 refs Grant No NIH NS-10367 The relationship between hypothalamic temperature and meta- bolic heat production was measured during wakefulness, slow-wave sleep, and paradoxical sleep in unrestrained kangaroo rats (Dipo- domys) Hypothalamic temperature was manipulated with chronical- ly implanted, water-perfused thermodes while cortical electro- encephalogram, electromyogram, metabolic rate, and body move- ment were continuously recorded During slow-wave sleep, in comparison to wakefulness, there is a lowered threshold hypotha- lamic temperature for the metabolic heat production response and a lowered proportionality constant relating rate of metabolic heat production to hypothalamic temperature During paradoxical sleep A77-10123 no increase in metabolic heat production could be elicited by lowering hypothalamic temperature, which indicates that the ther- moregulatory system is inoperative (Author) A77-10123 Ridge and Bayes identification for the quasi- linear human controller in compensatory tracking T 0 Kvalseth (Norges Tekniske Hogskole, Trondheim, Norway) IEEE Trans- actions on Systems, Man, and Cybernetics, vol SMC 6, Oct 1976, p 705-708 8 refs NSF Grant No GK-37419 The ridge and Bayes regression techniques as a tool for system identification are presented The application of this method is illustrated for the problem of estimating the impulse response sequence of a time-discrete human controller in a compensatory tracking task The estimates obtained are compared with the ordinary least squares estimates based on data from one experimental run (Author) A77-10137 * Influence of auditory fatigue on masked pure- tone thresholds D E Parker, R L Tubbs, P A Johnston, and L S Johnston (Miami University, Oxford, Ohio) Acoustical Society of America, Journal, vol 60, Oct 1976, p 881-885 8 refs Research supported by Miami University, Contracts No F33615-73-C-4002, No NAS9-14358 A description is presented of four related experiments involving conditions of 3-kHz low-intensity masking, a replication of experi- ment I with slight variations, 3-kHz high intensity masking, and 6-kHz low-intensity masking The frequencies of the tones which the observers detected were 3 and 6 kHz The observed change in masked-tone threshold as a function of fatigue is discussed It is found that masked-tone-detection thresholds remain essentially unchanged following fatigue if the maskmg-noise intensity is suffi- ciently great G R A77-10138 Identification of vowels excerpted from /I/ and 111 contexts Z B Bond (USAF, Aerospace Medical Research Laboratories, Wright-Patterson AFB, Ohio) Acoustical Society of America, Journal, vol 60, Oct 1976, p 906-910 8 refs USAF- sponsored research Two experiments were conducted investigating the identi- fiabihty of vowels excerpted from context Five phonetic contexts were investigated neutral (h-d), initial and final /I/, and initial and final hi Vowels were excerpted from these contexts by computer and presented to subjects for identification The consonantal contexts of initial and final A7 and /I/ affected the identification of the excerpted vowels in various systematic ways, as compared with the identification patterns of vowels excerpted from the neutral context (Author) A77-10139 Separation of speech from interfering speech by means of harmonic selection T W Parsons (Nicolet Scientific Corp , Northvale, N J ) Acoustical Society of America, Journal, vol 60, Oct 1976, p 911-918 12 refs Contract No F30602-74-175-C A common type of interference in speech transmission is that caused by the speech of a competing talker Although the brain is adept at clarifying such speech, it relies heavily on bmaural data When voices interfere over a single channel, separation is much more difficult and intelligibility suffers Clarifying such speech is a complex and varied problem whose nature changes with the moment-to-moment variation in the types of sound which interfere This paper describes an attack on the principal subproblem, the separation of vocalic speech Separation is done by selecting the harmonics of the desired voice in the Fourier transform of the input In implementing this process, techniques have been developed for resolving overlapping spectrum components, for determining pitches of both talkers, and for assuring consistent separation These techniques are described, their performance on test utterances is summarized, and the possibility of using this process as a basis for the solution of the general two-talker problem is briefly considered (Author) A77-10147 * An automated miniaturized Haploscope for testing binocular visual function T A Decker, R E Williams, C L Kuether, and D Wyman-Cornsweet (Baylor University, Houston, Tex) Optical Engineering, vol 15, July-Aug 1976, p 296303 6 refs Research supported by the Brown Foundation, Grants No NGR-44-012-099, No NGR-44-003-057 A computer-controlled binocular vision testing device has been developed as one part of a system designed for NASA to test the vision of astronauts during spaceflight The device, called the Mark III Haploscope, utilizes semi-automated psychophysical test pro cedures to measure visual acuity, stereopsis, phonas, fixation disparity and accommodation/convergence relationships All tests are self-administered, yield quantitative data and may be used repeatedly without subject memorization Future applications of this pro- grammable, compact device include its use as a clinical instrument to perform routine eye examinations or vision screening, and as a research tool to examine the effects of environment or work cycle upon visual function (Author) A77-10148 * Objective and automated measurement of dynamic vision functions M C Flom and A J Adams (California, University, Berkleley, Calif ) Optical Engineering, vol 15, July-Aug 1976, p 304-307 12 refs Grants No NGR-05-024-005, No DADA17-72-C-2083 A phoria stimulus array and electro-oculographic (EOG) arrange- ments for measuring motor and sensory responses of subjects subjected to stress or drug conditions are described, along with experimental procedures Heterophona (as oculomotor function) and glare recovery time (time required for photochemical and neural recovery after exposure to a flash stimulus) are measured, in research aimed at developing automated objective measurement of dynamic vision functions Onset of involuntary optokmetic nystagmus in subjects attempting to track moving stripes (while viewing through head-mounted binocular eyepieces) after exposure to glare serves as an objective measure of glare recovery time R D V A77-10149 A portable filter anomaloscope T P Piantanida (Florida, State University, Tallahassee, Fla ) Optical Engineering, vol 15, July-Aug 1976, p 325327 The author's own design of a portable field-use anomaloscope for examination of color vision genotype/phenotype characters in color matching by protanomalous and deuteranomalous subjects is described Design features and test procedures are related in detail Constraints on device design are indicated (accuracy and reliability in distinguishing between 7 9 color vision phenotype responses, in aiding detection of heterozygosity in carriers of defective color vision, compactness and ruggedness, low cost, adaptability to various power supplies encountered in fieldwork) Anomaloscopy is com- pared briefly to other color vision tests that fail to rule out extraneous variable (quality of illumtnant) R D V A77-10223 The influence of the position of the oxygen dissociation curve on oxygen-dependent functions of the isolated perfused rat liver II - Studies at different levels of hypoxia induced by decrease of blood flow rate J C Bakker, G C Gortmaker, and F G J Offenjns (Netherlands Red Cross Blood Transfusion Service, Amsterdam, Netherlands) Pflugers Archiv, vol 366, no 1, 1976, p 45-52 29 refs A77-10224 The assessment of position of stationary targets perceived during saccadic eye movement M Gresty and J Leech (National Hospital, London, England) Pflugers Archiv, vol 366, no 1, 1976, p 83-88 21 refs An experiment was performed to establish the accuracy with which visual targets perceived during saccadic eye movement are localized Subjects were presented with the task of executing saccades of 30 deg plus amplitude, passing through primary gaze, about the time of peak velocity, a 5-ms red flash was presented at A77-10661 some random position on a horizontal visual display Subjects were required to indicate the direction in which they thought the flash was localized by fixating in that direction Targets were localized with an average error of 5 to 6 deg, although the variance was high No systematic differences were found between conditions or subjects Error was unrelated to saccade velocity It is concluded that during saccadic eye movements, the appreciation of target position is maintained with an acceptable degree of accuracy (Author) A77-10250 Impact of radar irradiation on human systems K Natarajan and N Jagannathan (Indian Space Research Organiza- tion, Vikram Sarabhai Space Center, Trivandrum, India) Institution of Electronics and Telecommunication Engineers, Journal, vol 22, May 1976, p 326-329 6 refs A77-10273 Visibility of traffic control devices - Catering for the real observer A W Johnston, B L Cole, R J Jacobs, and A J Gibson (Melbourne, University, Melbourne, Australia) Ergo- nomics, vol 19, Sept 1976, p 591-609 27 refs Research supported by the Australian Road Research Board and Department of Civil Aviation It is argued that deficiencies of vision are sufficiently common and sufficiently profound in an unselected population to render it unwise to base the design of visual displays for man-machine systems on data obtained using unrepresentative samples of observers selected to exclude those with visual defects A series of experiments is reviewed which investigated signal recognition by observers with defective color vision, contrast detection by observers with normal and blurred vision, and the effect of blurred vision on the legibility of alphanumeric and symbolic information displays (standard road signs) It is concluded that the ergonomic design of visual displays in transport systems should be an optimization of engineering design and population selection F G M A77-10274 Drug effects on heart rate and heart rate variability during a prolonged reaction task A W K Gaillard (Central Organization for Applied Scientific Research in the Nether- lands TWO, Institute for Perception TNO, Soesterberg, Netherlands) and D A Trumbo Ergonomics, vol 19, Sept 1976, p 611-622 16 refs Effects of task difficulty, time on task, an amphetamine, and a barbiturate on heart rate during prolonged test sessions are in- vestigated In the experiment reported, eight pairs of male subjects performed serial reaction tests over the course of three hours on different days At each session, the subjects were given an amphe- tamine derivative, a barbiturate, a placebo, or no medication The time between successive heart beats was measured, and four different test scores were computed The results show that both time on task and the amphetamine apparently acted directly on heart rate, while the barbiturate and task difficulty influenced heart rate indirectly through increased mental effort The time-on-task results are shown to suggest a loss of activation over time F G M A77-10341 Duration of whole-body vibration exposure Its effect on comfort M J Griffin and E M Whitharr (Southampton, University, Southampton, England) Journal of Soundand Vibration, vol 48, Oct 8, 1976, p 333-339 13 refs An experiment was conducted to determine whether the relative discomfort produced by 4 Hz and 16 Hz sinusoidal whole body vertical vibration was dependent on the duration of the vibration exposure Each of eight seated subjects was exposed to 36-mmute vibration sessions using an electrodynamic vibrator, both sessions consisting of ten second periods of 4 Hz and 16 Hz vibration alternating continuously Subjects were required to control the intensity of the test motion to compensate for periodic changes in its intensity made by the experimenter It was found that the relationship between the average levels of the two motions when adjusted to produce similar discomfort was independent of vibration duration B J A77-10600 H Psychomotor test performance and sleep pat- terns of aircrew flying transmendional routes L Buck (National Research Council, Control Systems and Human Engineering Labora tory, Ottawa, Canada) Canada, National Research Council, Division of Mechanical Engineering and National Aeronautical Establishment, Quarterly Bulletin, no 2, 1976, p 19-33 17 refs Pilots and flight attendants flying scheduled services between Vancouver and Tokyo and between Toronto and Rome were tested on a tracking task before and after flights in each direction Flights were included in schedules involving both 24 hour and 7-day layovers at the overseas station During these periods they recorded their sleep patterns The data showed that following flight subjects made an immediate attempt to adapt their behaviour to local time and that changes in their performance scores could be interpreted on that basis It was concluded that behavioural arcadian rhythms adapt rapidly to a new time-zone (Author) A77-10651 * Preliminary results of morphological and cyto- chemical studies on animals after a stay of 22 days in space flight aboard the Cosmos 605 satellite (Predvantel'nye itogi morfologi- cheskikh i tsitokhimicheskikh issledovann zhivotnykh, nakho- divshikhsia 22 sutok v kosmicheskom polete na bortu ISZ 'Kosmos- 605') V V Portugalov Akademna Nauk SSSR, Izvestna, Serna Biologicheskaia, May-June 1976, p 418-429 In Russian Histological and cytochemical methods are used to study the condition of vital organ systems in rats who have completed a 22-day orbital flight aboard the Cosmos 605 satellite It is found that the most pronounced changes occurred in the muscular, lymphoid, hematopoietic, osteal, and other relevant tissues The observed changes were not specific to space flight and might be obtained during experiments on animals under ground-based conditions The changes were essentially reversible and virtually disappeared by the 27th postflight day S D A77-10652 ft Biophysical analysis of the action of Coriolis acceleration on the vestibular analyzer (Biofizicheskn anahz deistviia uskorenn Konolisa na vestibuharnyi analizator) E V Lapaev and N B Platonov Akademna Nauk SSSR, Izvestna, Seri'a Biologicheskaia, May June 1976, p 449-452 7 refs In Russian Coriolis acceleration as an adequate stimulus of the vestibular analyzer is regarded as one of the possible causes for the occurrence of motion sickness Results are presented for a biophysical analysis of the action of the Coriolis acceleration on the vestibular analyzer It is theoretically shown that rotational acceleration and Coriolis acceleration have a similar physical structure An analogy between Coriolis acceleration and normal acceleration is also demonstrated Both the horizontal and vertical semicircular canals and the otolith system are shown to be subject to stimulation Experimental studies on rabbits revealed that the basic trigger mechanism for the onset of vestibular responses to Coriolis acceleration is the rotational moment resulting from a difference between the magnitudes of the Coriolis acceleration at different points of the semicircular canals S D A77-10661 H Effect of hydrocortisone and adrenocortico- tropin on the conformational state of proteins in the brain and muscles (Do pitanma pro vphv gidrokortizona i adrenokortiko- tropnogo gormona na konformatsimn stan bilkiv golovnogo mozku ta rn'iaziv) A la Mestechkina, L M Kalms'ka, and V I Kravchenko (Knvs'kn Naukovo-Doshdnii Institut Endokrinologn ta Obminu Rechovin, Kiev, Ukrainian SSR) Akademna Nauk Ukram- s'koi RSR, Dopovidi, Serna B • Geologichm, Khimichni ta Biologich- mNauki.Aug 1976, p 730-733 14 refs In Ukrainian A77-1070O A77-10700 * Studies on the nature of plasma growth hormone S Ellis, R E Grmdeland, T J Reilly, and S H Yang (NASA, Ames Research Center, Biomedical Research Div, Moffett Field, Calif ) In Growth hormone and related peptides Proceedings of the Third International Symposium, Milan, Italy, September 17-20, 1975 Amsterdam, Excerpta Medica (Excerpta Medica Inter- national Congress Series, No 381), 1976, p 75-83 Srefs The paper presents further evidence for the existence of two discrete forms of growth hormone in human plasma, one which is detectable by both radioimmunoassay and bioassay and is immuno- reactive, and the other, termed 'bioactive', which is detected by tibial bioassay but shows little reactivity with currently available antisera to pituitary growth hormone The same division of immunoactive and bioactive growth hormone occurs in rats, though with less disparity Tests on rats indicated that the bioactive hormone is preferentially released into jugular vein plasma and that plasma concentrations of the bioactive hormone can be enhanced by insulin administration The bioactive hormone was detectable by tibial assays in Cohn fractions IV, IV-1, and IV-4, and could be concentrated about 40-fold by fractionation with (NaP03)6 and (NH412S04 PTH A77-10709 * Cardiovascular and pulmonary dynamics by quantitative imaging E H Wood (American Heart Association, New York, N Y ) Circulation Research, vol 38, Mar 1976, p 131-139 41 refs Research supported by the American Heart Association, Grants No NIH-HI-4664, No NIH-RR-7, No NCR 24-003-001, Contract No F44620-71-C-0069 The accuracy and range of studies on cardiovascular and pulmonary functions can be greatly facilitated if the motions of the underlying organ systems throughout individual cycles can be directly visualized and readily measured with minimum or preferably no effect on these motions Achievement of this objective requires development of techniques for quantitative nomnvasive or minimally invasive dynamic and stop-action imaging of the organ systems A review of advances in dynamic quantitative imaging of moving organs reveals that the revolutionary value of cross-sectional and three- dimensional images produced by various types of radiant energy such as X-rays and gamma rays, positrons, electrons, protons, light, and ultrasound for clinical diagnostic and biomedical research applica- tions is just beginning to be realized The fabrication of a clinically useful cross-section reconstruction device with sensing capabilities for both anatomical structural composition and chemical com- position may be possible and awaits future development S D A77-10702 * Halobactenum saccharovorum sp nov, a carbohydrate-metabolizing, extremely halophihc bacterium G A Tomlmson (Santa Clara, University, Santa Clara, Calif ) and L I Hochstem (NASA, Ames Research Center, Moffett Field, Calif ) Canadian Journal of Microbiology, vol 22, no 4, 1976, p 587-591 12rsfs Contract No NCAR-685-412 The previously described extremely halophihc bacterium, strain M6, metabolizes a variety of carbohydrates with the production of acid In addition, the organism produces nitrite (but no gas) from nitrate, is motile, and grows most rapidly at about 50 C These characteristics distinguish it from all previously described halophihc bacteria in the genus Halobactenum It is suggested that it be designated as a new species, Halobactenum saccharovorum (Author) A77-10703 * Light-induced membrane potential and pH gradient in Halobactenum halobium envelope vesicles R Renthal and J K Lanyi (NASA, Ames Research Center, Biological Adapta- tion Branch, Moffett Field, Calif) Biochemistry, vol 15, no 10, 1976, p 2136-2143 37 refs A77-10704 * Light-induced glutamate transport in Halo- bacterium halobium envelope vesicles II - Evidence that the driving force is a light-dependent sodium gradient J K Lanyi (NASA, Ames Research Center, Biological Adaptation Branch, Moffett Field, Calif ), R Renthal (Texas, University, San Antonio, Tex ), and R E MacDonald (NASA, Ames Research Center, Biological Adaptation Branch, Moffett Field, Calif , Cornell University, Ithaca, N Y ) Biochemistry, vol 15, no 8, 1976, p 1603-1610 43 refs A77-10705 * Monocarboxylic acids from oxidation of acyclic isoprenoid alkanes by Mycobactenum fortuitum R E Cox (Liverpool, University, Liverpool, England), J R Maxwell, and R N Myers (Bristol, University, Bristol, England) Lipids, vol 11, no 1, 1976, p 72-76 11 refs Grant No NGL-05-003-003 Mycobactenum fortuitum utilizes certain stereoisomenc mix- tures of individual multimethyl branched alkanes as sole carbon source, including 2,6(R), 10(S), 14(RS)-tetramethylhexadecane, 2,6(R), 10(S), 14(RS)-tetramethylheptadecane, 2,6(RS), 10(RS)- trimethyltetradecane, and 2,6(R), 10(S)-tnmethylpentadecane Prod- ucts of oxidation isolated from the bacterial lipids were acids derived predominantly from oxidation of the isopropyl terminus of each alkane, except in the case of 2,6(RS), 10(RS)-tnmethyltetradecane With the latter, acids from oxidation at either terminus were detected in comparable proportions (Author) A77-10799 Effects of psychosocial stimuli on plasma renm activity in rats 0 M damage, C S Sanford, A J Vander, and D R Mouw (Michigan, University, Ann Arbor, Mich ) American Journal of Physiology, vol 231, Oct 1976, p 1290-1294 33 refs Research supported by the Michigan Heart Association Unanesthetized male albino rats (200-250 g) were subjected to the open-field (novel environment) procedure and to the presence of a hungry cat as psychosocial stimuli to study the variation of the plasma renm activity (PRA) in the blood of these animals after decapitation It is found that a 30-mm exposure to the cited psychosocial stimuli produced statistically significant increases in •PRA in rats maintained on either a standard (1% NaCI) or sodium-free diet Prior treatment with propranolol did not complete- ly eliminate the PRA It is concluded that psychosocial stimuli can significantly enhance renm secretion and that this response is mediated, at least in part, by the sympathetic nervous system S D A77-10800 Effects of chronic hypoxia and dietary restric- tion on myocardial enzyme activities S E Barrie and P Harris (London, University, London, England) American Journal of Physi- ology, vol 231, Oct 1976, p 1308-1313 17 refs Research suppojted by the Nuffield Foundation Results are presented of an experimental study of the activities of a range of enzymes from different catabolic pathways and of cytoplasmic and mitochondnal origin in homogenates of left and right ventricles of guinea pigs after 14- and 28-day exposure to 400 mm Hg barometric pressure Two control groups of animals were used, one free fed and the other restricted to the amount of food chosen by the hypobanc group The left and right ventricles were considered separately so as to distinguish the effects of hypoxia from those of hypertrophy All the animals developed anorexia and right ventricular hypertrophy A major conclusion is that there are significant differences in a number of enzyme activities between the left and right ventricles Dietary restriction is associated with a decrease in glycogen phosphorylase, nexokmase, and succmate dehydrogenase activity and an increase in the M-subumts of lactate dehydrogenase Chronic hypoxia per se does not evoke an increase in M-subumts ' S D A77-10887 * H Joint inflight biomedical experiments per- founed during the ASTP spaceflight G R Taylor (NASA, Johnson Space Center, Houston, Tex ), T D Rogers, M E Brower, and K Kropp (Northrop Services, Inc, Houston, Tex ) International A77-11097 Astronautical Federation, International Astronaut/cat Congress, 27th, Anaheim, Calif, Oct 10-16. 1976. Paper 76-031 9p 18 refs Two joint inflight biomedical experiments were conducted during the unique Apollo-Soyuz Test Project (ASTP) spaceflight One experiment evaluated rh'ythmicity of spore production of Streptomyces levons The other evaluated components of the infectious disease process by measuring alteration in (1) the composition of the microbial population inhabiting USA and USSR crewmembers and spacecraft, (2) the ability of each crewmember's defense mechanism to resist infection, and (3) the ability of certain microorganisms to originate infections These two experiments are described and the major results discussed (Author) each sample, and membrane filtration counts were used to construct dose response curves, relationships and results are discussed herein (Author) A77-10990 * The diurnal variation of neutral hepatic fructose 1,6-diphosphatase in partially inbred populations of rats and in outbred populations of Microtus montanus P U Ashman, S L Lampkm, K G Boutte, L A Dillon, and K R Williams (Louisiana, Xavier University, New Orleans, La I Comparative Biochemistry and Physiology, vol 53B, 1976, p 315-318 14 refs Grants No NCR 19-007-004, No NIH-RR-08008 A77-10888 * H Effect of hypovolemia, infusion, and oral rehydration on gradual onset +Gz acceleration tolerance J E Greenleaf, P J Brock, R F Haines, S A Rositano, L D Montgomery, and L C Keil (NASA, Ames Research Center, Moffett Field, Calif) International Astronautical Federation, International Astronautical Congress, 27th, Anaheim, Calif, Oct 10-16, 1976, Paper 76-039 9p 25 refs Grant No NCA2-OR180-506 The purpose of this study was to determine the effect of blood withdrawal, blood infusion, and oral fluid intake on +Gz tolerance at an acceleration rate of 0 5 G/min Six healthy men aged 21 27 yr were centrifuged after the withdrawal of 400 ml of blood (hypo- volemia) from each man, they were centrifuged again following -blood infusion (Phase I) Three weeks later the men were accelerated after similar hypovolemia and again after consuming 800 ml of an isotomc NaCI drink (Phase II) Phase I hypovolemia resulted in a reduction in tolerance in all subjects from a mean control level of 642 + or - 035 mm to 545 + or - 0 17 mm (-151%, p less than 005) Both infusion and drinking returned tolerances to control levels During acceleration there were significant (p less than 005) increases in plasma vasopressm levels to 35 pg/ml, these were not influenced appreciably by infusion or drinking In all acceleration runs there was an obligatory shift (loss) of plasma volume and electrolytes, especially potassium, regardless of the experimental treatments Oral rehydration is shown to be as effective as blood replacement in restoring +Gz acceleration tolerance decrements due to hypovolemia (Author) A7710889 " A Space Shuttle galley system B Cooper (Fairchild Republic Co , Farmmgdale, N Y ) International Astro- nautical Federation, International Astronautical Congress, 27th, Anaheim, Calif, Oct 10-16, 1976, Paper 76-044 4p Problems, goals, constraints, and initial tasks in design and improvements of food logistics, food preparation, food acceptance, water and cooking systems, and trash management onboard Space Shuttle are discussed Rehydratables, ready-to-eat (RTE) foods, beverages, and thermostabilized (canned) foods are discussed in regard to handling, calories and nutrient value, earthhke familiarity in appearance, consumer evaluation and complaints, stability, stow- ability, safety, and contribution to overall menu Food and water system stowage space as needed per length of mission (assuming crew of seven), food logistics systems adaptability to later improvements, and selection of food oven (convection rather than conduction oven) are dealt with R D V A77-10988 * Analytical notes - Electrochemical method for early detection and monitoring of cohforms J R Wilkins (NASA, Langley Research Center, Hampton, Va ) and E H Boykin (Northrop Services, Inc , Hampton, Va I American Water Works Association, Journal, vol 68, May 1976 7 p 11 refs An electrochemical method for detecting bacteria, based on a linear relationship between inoculum size and the time of hydrogen evolution, was tested for the early detection and monitoring of coliforms in naturally contaminated estuarme and fresh water samples Standard methods for coliform analysis were performed on A77-10991 * Average latitudinal variation in ultraviolet radiation at the earth's surface F S Johnson (Texas, University, Richardson, Tex ), T Mo, and A E S Green (Florida, University, Gainesville, Fla ) Photochemistry and Photobiology, vol 23,1976, p 179-188 17 refs Research supported by the U S Department of Transportation, Grant No NGL-44 004-026 Tabulated values are presented for ultraviolet radiation at the earth's surface as a function of wavelength, latitude, and season, for clear sky and seasonally and latitudmally averaged ozone amounts These tabulations can be combined with any biological sensitivity function in order to obtain the seasonal and latitudinal variation of the corresponding effective doses The integrated dosages, based on the erythemal sensitivity curve and on the Robertson-Berger sun burn meter sensitivity curve, have also been calculated, and these are found to vary with latitude and season in very nearly the same way as 307 and 314 nm radiation, respectively (Author) A77-11048 Echocardiographic measurement of cardiac output using the mitral valve and aortic root echo A V Lalani (Alberta, University, Edmonton, Canada) and S J K Lee (Univer- sity Hospital, Edmonton, Canada) Circulation, vol 54, Nov 1976, p 738-743 23 refs A77-11049 * The posterior aortic wall echocardiogram - Its relationship to left atnal volume change B L Strunk, J W Fitzgerald, M Lipton, R L Popp, and W H Barry (Stanford University Hospital, US Veterans Administration Hospital, Stanford University, Palo Alto, Calif ) Circulation, vol 54, Nov 1976, p 744-750 13 refs Research supported by the Bay Area Research Council, Grants No NIH-HL-14174, No NIH-1-P01-HL-15833, No NGL-05-020-305 A77-11097 Plasma angiotensm II levels in hypoxic and hypovolemic stress in unanesthetized rabbits R M Zakheim, A Molteni, L Mattioli, and M Park (Kansas, University, Medical Center and Hospital, Kansas City, Kan ) Journal of Applied Physiology, vol 41, Oct 1976, p 462-465 24 refs Research supported by the University of Kansas and Kansas Heart Association Plasma levels of angiotensm II were determined by radio- immunoassay in unanesthetized white rabbits exposed to acute hypoxia, chronic hypoxia, or hypovolemic stress Angiotensm II levels significantly decreased after 10 mm of acute hypoxia in normal rabbits and significantly increased when the same procedure was applied to animals previously exposed to hypoxia by 6-8 days of permanence in the hypobanc chamber or sodium deprivation Chronic hypoxia resulted in a temporary increase of angiotensm II already evident on the 3rd day, but maximal at the 9th day with return to normal values within 16 days Hypovolemic stress resulted m the expected rise of angiotensm II levels 10 mm postbleedmg both in normal and acclimatized rabbits The response of the renin- angiotensm-aldosterone system to hypoxic and hypovolemic stress is different The direction and magnitude of the response to hypoxia depends on the underlying state of activation of the system and the cardiovascular condition of the animal at.the time of hypoxic stress (Author) A77-11098 A77-11098 Cyclic hypoxic pulmonary vasoconstriction induced by concomitant carbon dioxide changes J L Benumof, J M Mathers, and E A Wahrenbrock (California, University, San Diego, Calif ) Journal of Applied Physiology, vol 41, Oct 1976, p 466-469 7 refs Research supported by the American Heart Association, Grant No PHS-HL-19169 The stability of acute lobar hypoxic pulmonary vasoconstriction was examined In 12 mongrel dogs the left lower lobe (LLL) was selectively ventilated with a constant minute volume with nitrogen and the electromagnetically measured fraction of the cardiac output perfusing the LLL and the LLL end-tidal C02 concentration were observed for 1 h It is found that both the fraction of the cardiac output perfusing the LLL and the LLL end-tidal C02 concentration initially decreased during LLL hypoxia and then oscillated in a progressively damped fashion When LLL end tidal C02 was kept constant by C02 infusion during LLL hypoxia or when LLL hypoxia was induced by LLL atelectasis, no oscillations were observed It is concluded that if minute ventilation of a hypoxic area of lung is kept constant, then decreased regional blood flow decreases regional alveolar P(C02) Blood flow to an acutely hypoxic area will thus be oscillatory (Author) A77-11099 Anaerobic threshold and maximal aerobic power for three modes of exercise J A Davis, P Vodak, J H Wilmore, J Vodak, and P Kurtz (California, University, Davis, Cal i f) Journal of Applied Physiology, vol 41, Oct 1976, p 544-550 20 refs Contract No F44620-72-C-0011 Alterations in selected respiratory gas exchange parameters have been proposed as sensitive, noninvasive indices of the onset of metabolic acidosis (anaerobic threshold (AT)) during incremental exercise The objectives were to investigate the validity and feasibil- ity of AT detection using routine laboratory measures of gas exchange, i e, nonlinear increases in minute ventilation and minute C02 production and abrupt increases in fraction of oxygen in expired gas The study examined the comparability of the AT and maximum oxygen consumption among three modes of exercise (arm cranking, leg cycling, and treadmill walk-running) with double determinations obtained from male sublets No significant differ- ence was found between the leg exercise modes (cycling and walk-running) for the AT while all pairwise arm versus leg com- parisons were significantly different Using additional subjects performing leg cycling tests, a significant correlation was found between gas exchange AT measurements and venous blood lactate AT measurements The gas exchange AT is therefore a valid and valuable indirect method for the detection of the development of lactic acidosis during incremental exercise (Author) A77-11100* Cerebellar pressor response in the dog K J Dormer and H L Stone (Texas, University, Galveston, Tex ) Journal of Applied Physiology, vol 41, Oct 1976, p 574-580 25 refs Grants No NIH-HL-05145, No NGR-44-088-002 A fastigial pressor response has been elicited in the anesthetized mongrel dog Stimulation within the rostral portions of this nucleus results in mean arterial pressure rises up to 150 mmHg above control A proportional tachycardia is simultaneously evoked which may rapidly attain heart rates of 190 beats/mm above control levels Peak tachycardias immediately subside and often the heart rate declines below control values during stimulation while arterial pressure remains elevated When either the carotid sinuses were isolated by ligation or a bilateral vagotomy was performed, the fastigial tachycardia was sustained The response could still be attained when submaximal doses of alpha-chloralose anesthesia or high levels of barbiturates (30-40 mg/kg) were given Both portions of the response result from widespread sympathetic activation, however, buffering of the response through the baroreceptor reflexes is only demonstrated in the cardiac segment of the response (Author) A77-11166 Simultaneous three-channel signal detection - Performance and criterion as a function of order of report L D Pohlmann (USAF, Human Resources Laboratory, Williams AFB, Ariz ) and R D Sorkm (Purdue University, Lafayette, Ind ) Perception and Psychophysics, vo'l 20, no 3, Sept 1976, p 179-186 34 refs NSF supported research Earlier studies have shown that observers can perform two- channel tasks with the same efficiency as single channel tasks as long as no more than one signal or signal-like event is present In this paper, results are presented for experiments conducted on three female students with normal hearing to evaluate performance on a task requiring detection of three simultaneous and independent sinusoidal signals and compare this performance to single-channel performance The signals and noise were monaural, and all signals were 100 msec in duration and were presented simultaneously during a single visually-marked 100 msec observation interval The data for each channel were analyzed conditional on the stimulus response events occurring in the remaining channels and conditional on the order of report It is found that the decrement in performance in any channel in the three-channel task increases with increasing number of signals and/or yes-responses present in the remaining channels The data obtained lend support to a model comprising an independent- channel perceptual processor feeding into a cognitive processor susceptible to channel interactions S D A77-11309 ,n the histochemical indices of the liver in white rats (Vlnanie sil'nogo postoiannogo magmtnogo polia i gipomagnitnoi okruzhaiushchei sredy na gistokhimtcheskie pokaza- teh pechem belykh krys) I V Shust and I M Kostimk Kosmi- cheskaia Biologna i Aviakosmicheskaia Meditsma, vol 9, Nov Dec 1975, p 19-25 16 refs In Russian A77-11355 ri Investigation of the physiological activity of Chlorella vulgaris following an exposure to space flight factors aboard the Salyut orbital station (Issledovanie fiziologicheskoi aktivnosti khlorelly posle vozdeistvna faktorov kosmicheskbgo poleta na bortu orbital'noi stantsn 'Sahut') T B Galkma and G I Meleshko Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 9, Nov-Dec 1975, p 25-30 5 refs In Russian ekosistemy s penodicheski rabotaiushchim avtotrofnym zvenom II - Ustoichivost' penodicheskikh rezhimov) V G Shabel'nikov Kosmi- cheskaia Biologna i Aviakosmicheskaia Meditsma, vol 9, Nov Dec 1975, p 36 40 In Russian Available experimental data on the influence of atmospheric composition on the photosynthetic productivity of an intensive microalgal culture are used to construct a mathematical model of an ecological system that is closed with respect to gas exchange and operates in alternating light-dark cycles The study determined the type of the periodic time dependence of the steady state atmosphere of the ecological system Conditions for the existence and stability of the steady state atmosphere are identified S D A77-11358 ff Human tolerance to +Gz accelerations during heating of the body (Perenosimost' chelovekom uskorenn napravle- nna +Gz v uslovnakh peregrevamia organizma) A R Kotovskaia, R A Vartbaronov, and V M Khrolenko Kosmicheskaia Biologna I Aviakosmicheskaia Meditsma, vol 9, Nov-Dec 1975, p 41-45 11 refs In Russian Experiments were conducted on 25 healthy male subjects subjected to centrifugal accelerations to study their tolerance to acceleration under varying body temperatures A regression analysis of the data indicates that at a body temperature of 37 3 C a reduction in +Gz acceleration tolerance is expected in some of the subjects, but at 37 6 C and more the reduction occurs in most of the subjects The results obtained allow practical recommendations to be made relative to acrobatic flights in a hot climate S D A77-11359 # Effect of positive longitudinal acceleration on the transmission properties of a human operator (0 vlnann polo- zhitel'noi prodol'noi peregruzki na peredatochnye svoistva chelo- veka-operatora) V A Bodner and V K Filosofov Kosmicheskaia Biologna i Aviakosmicheskaia Meditema, vol 9, Nov -Dec 1975, p 4548 In Russian Results are presented for an experimental study of the effect of +Gz accelerations on the transmission properties of a human operator involved in the closed loop of a tracking system The quality of tracking a complex signal upon exposure to accelerations of different magnitudes is assessed The result of increased accelera- tion and time exposure is that the distribution of tracking errors of the human operator deviates from a bell-shaped and approaches a uniform distribution Accelerations aftereffects disappear in about 2 mm S D A77-11356 # Control of mineral nutrition of higher plants in biological life support systems (Upravleme mmeral'nym pitamem vysshikh rastenn v biologicheskikh sistemakh zhizneobespechemia) V I Rozhdestvenskn, M V Vil'iams, I V Tsvetkova, E V Lebedeva, T P Alekhma, G G Rusakova, and V M Simonov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 9, Nov Dec 1975, p 3035 In Russian Results are presented regarding the development and expen mental study of a program for controlling the mineral nutrition of higher plants for use in biological life support systems The control method is based on the correlative relationship between consumption of mineral elements and increase of biomass Experiments on carrots grown aeropomcally indicate that mineral nutrition of plants can be controlled by means of a corrective nutrient solution applied according to the protocols obtained from studies on increase in the dry biomass of the plant S D A77-11357 # Model of an ecological system closed relative to gas exchange with a periodically operating autotrophic unit II Stability of periodic cycles (Model' zamknutoi po gazoobmenu A77-11360 ff Cognitive activity of man during adaptation to short-term weightlessness (Poznavatel'naia deiatel'nost' hchnosti pri adaptatsn k kratkovremennoi nevesomosti) O N Kuznetsov, I A Kolosov, A V Kahberdm, and A A Prusskn Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 9, Nov -Dec 1975, p 48-54 27 refs In Russian Psychological methodology of personality assessment is used to study differences in individual experiences of human subjects exposed to short-term weightlessness for the first time It is found that subjects of the objective-productive type of cognitive behavior exhibit the most rapid and adequate adaptation to weightlessness Individuals of the subjective and nonproductive types of cognitive activity showed great difficulties in adapting to weightlessness, marked by abnormal psychic states such as the 'world peril' syndrome and psychic alienation Anticipation of weightlessness on the basis of previous objective information is shown to facilitate orientation and self control of man under weightlessness conditions SD A77-11361 A77-11361 ff Adaptation of the cardiovascular system to negative stressful acceleration during repeated antiorthostatic ex- posures (Adaptatsna serdechno-sosudistoi sistemy k otntsatel'noi gravitatsionnoi nagruzke pri povtornykh antiortostaticheskikh vozdeistvnakh). D A Alekseev, Kh Kh larullin, and T D Vasil'eva Kosmicheskaia Biologna i Aviakosmicheskaia MediKina, vol 9, Nov -Dec 1975, p 55-61 25 refs In Russian A77-11362 * Functional interdependence of the visual and auditory analyzers during extremal stimulation (Vzaimozavisimost' funktsn zntel'nogo i slukhovogo analizatorov pri ekstremal'noi stimuliatsn) I F 0'iakonov and A S Mozzhukhin Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 9, Nov-Dec 1975, p 61-65 In Russian Psychophysiological methods are used in an experimental study on 10 male subjects aged 19-22 yr to evaluate the effect of intense photostimulation on the functional state of the visual analyzer, along with the effect of an extremal light stimulus on the hearing function It is shown that a pulsed acoustic stimulus promotes the recovery of peripheral photosensitivity, does not affect central photosensitivity, improves the acuity of color differentiation, enlarges the field of vision for red and green, and reduces the electrical sensitivity of the eye and critical frequency for the vanishing of light flashes Exposure to a superlummous flash is found to reduce the absolute hearing thresholds, the electrical sensitivity of the eye, and the critical frequency for the fusion of the electric stimuli of the auditory system The results point to the possibility of increasing the sensitivity of an analyzer through a short-term intense stimulation of another analyzer S D A77-11363 ff Study of the dynamics of mental-working capacity in flight personnel with hypertensive disease for prognosis of their occupational activity (Izucheme dinamiki psikhicheskoi rabotosposobnosti letnogo sostava pri gipertomcheskoi bolezni v tsehakh prognozirovanua professtonal'noi deiatel'nosti) K K loseham Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 9, Nov-Dec 1975, p 65-70 8 refs In Russian A77-11364 # Working capacity of man during stay at high altitudes (Rabotosposobnost' cheloveka vo vremia prebyvamia v gorakh) M T Turkmenov and D I Imankulov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 9, Nov Dec 1975, p 70-75 32 refs In Russian Experiments were conducted on 11 lowland male subjects aged 18-24 yr who have ascended to an altitude of 3200 m without preliminary training The objectives were to determine when maximal working capacity is normalized at high altitudes and to assess the extent to which this capacity can be increased when subjects experience additional physical stress During"their stay at high altitude, the subjects were involved in daily gymnastic and sports activities, and they periodically and gradually climbed to further heights up to 4000 m, such an adaptive regime was called 'pulsating' mode of adaptation The phasal variation of maximal working capacity during a short-term stay at high altitude was such that in the first 10 days of stay the working capacity was reduced by 12-13%, but on the 41st-42nd day it increased by 25% The working capacity during a readaptation period is found to persist for 2 months at a level of 25-30% higher than the initial level The suitability of the 'pulsating' mode of adaptation for enhancing physical working capacity of the human organism is thus demon- strated S D A77-11365 # Investigation of the composition of volatile compounds m sweat and urine m man (Issledovame sostava letuchikh soedmenn pota i mochi u cheloveka) V P Savina, N L Sokolov, and E A Ivanov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 9, Nov-Dec 1975, p 76-78 9 refs In Russian A procedure based on gas chromatography is outlined for qualitative analysis of the volatile compounds in the urine and sweat released by individuals placed in a hermetic chamber Harmful metabolites liberated in sweat and urine are identified The result of lack of purification of the environment in the hermetic chamber is that in the case of low perspiration of about 500 ml/day the amount of released volatile metabolites is enough to contaminate the environment for a chamber space of less than 3 cu m per person The results obtained may be used in formulating means for purification of the environment of manned hermetic chambers from toxic and foul-smelling substances SO A77-11366 # Radioprotective effect of mexamm and cysta- min on animals exposed to hypokmesia and ionizing radiation (Radiozashchitnyi effekt meksamma i tsistamma na orgamzm zhivot- nykh pri gipokmezn i lomziruiushchei radiatsii) L la Kolemeeva, V S Shashkov, and B B Egorov Kosmicheskaia Biologna i Aviakosmi- cheskaia Meditsma, vol 9, Nov Dec 1975, p 78,79 In Russian A77-11367 ff Hypokmesia and macroscopic changes in seminal vesicles (Gipokmezna i makrometncheskie izmenenna semen- nykh puzyrkov) L P Smol'sku Kosmicheskaia Biologna i Aviakos- micheskaia Meditsma, vol 9, Nov-Dec 1975, p 79-82 5 refs In Russian A77-11368 ff Pathophysiology of long-term hypokmesia (Patofiziologiia dhtel'noi gipokmezn) E A Kovalenko Kosmi- cheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Jan Feb 1976, p 315 77 refs In Russian The article reviews the literature on effects of long term immobilization (periods of 10 days up to 70 days or beyond) on animal and human organisms Effects on tissue respiration, enzyme activity, metabolic rate, hormonal function (glycolysis, AMP/ADP/ATP balance, phosphodiesterase activity), lack of periodic stimuli for DNA to RNA to protein synthesis, lowered uptake of radiotagged ammo acids in mouse muscle protein, body weight loss, retarded growth in juveniles, weakening of efferent imputation and afferent feedback, effect on cardiovascular system and hemo- dynamics, on lower half of body, water/salt metabolism, immuno- logical responses, EEC, sleep, irritability level, endocrmal and nervous function, bone tissue, teeth, and hemopoiesis Compensatory mechanisms and compensatory effects of horizontal position are considered, and a pathogenesis flowchart is included R D V A77-11369 ff The Soyuz-Apollo experimental flight - Pre- liminary results of medico-biological research carried out during flight of Soyuz-19 (Eksperimental'nyi polet 'Soiuz-Apollou' - Predva- ritel'nye rezul'taty mediko-biologicheskikh issledovann, vypolnen- nykh vo vremia poleta korablia 'Soiuz-19') E I Vorob'ev, 0 G Gazenko, N N Gurovskn, lu G Nefedov, B B Egorov, I I Spitza, E N Binukov, I I Brianov, A V Eremm, and A D Egorov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Jan Feb 1976, p 1522 In Russian Preliminary results of microbiological and physiological tests are reported for pre flight, in-flight, and post-flight programs Fungus and microbial experiments carried out jointly by the two crews are listed Information is provided on the daily physiological and pharmaceutical regimes of the cosmonauts, ECG data, pressure discrepancies between the two spacecraft quarters, dumping of pressure on Soyuz 19 for equalization, and absence of anticipated decompression disturbances Post flight ophthalmological, g load, blood chemistry, blood count, weight change, urine analysis and other physiological tests are reported Slight reversible shifts in metabolic function are reported, and the value of pre-flight con- ditioning and training exercises for minimizing m fligh' discomfort is confirmed R D V 10 A77-11380 A77-11370 # Study of phosphatase activity in the bone tissue and blood serum during 90-day hypokmesia (Izuchenie aktivnosti fosfataz v kostnoi tkani i syvorotke krovi pri 90-iutocnnoi gipokmezn) A Menendes, R A Zavahshma, and A A Pokrovskn Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, Jan-Feb 1976, p 22-26 ISrefs In Russian Experiments were conducted in which the activity of alkaline and acid phosphatases in the femoral epiphysis and diaphysis and the activity of alkaline phosphatase of Wistar rats that were subletted to 90-day hypokmesia were studied At the beginning of the hypo- kmesia experiment, the activity of both enzymes decreased, the decrease of alkaline phosphatase being more significant After a period of stress, the activity of both enzymes was seen to increase, especially that of acid phosphatase in the diaphysis B J A77-11371 ft The effect of different regimes of motor activity on the adaptation of man to high altitude (Vluanie razhchnykh rezhimov dvigatel'noi aktivnosti na protsessy adaptatsu cheloveka k uslovnam vysokogor'ia) V I Korol'kov, M M Mirrakhimov, A D Ozhailobaev, 0 N Narbekov, N la lusupova, and V V Verigo Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, Jan-Feb 1976, p 26-31 19refs In Russian A77-11375 H State of the labyrinth tonic reflexes of posi- tion during the administration of trace elements to rabbits /copper, manganese, and cobalt/ (Sostoiame labirmtnykh tomcheskikh re- fleksov polozhemia pri vvedenn krohkam mikroelementov /medi, margantsa i kobal'ta/) V S Raitses and S P Voroshilovskaia Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, Jan-Feb 1976, p 45-50 12refs In Russian A77 11376 ~ Effect of transverse accelerations on the motor function of the stomach (Vluanie poperechno-napravlennykh usko- renu na motornuiu funktsnu zheludka) V V Murashko and K V Smirnov Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, Jan-Feb 1976, p 50-54 10refs In Russian Experiments were conducted to investigate the effect of transverse accelerations on the motor functions in hungry and fed states of the stomachs of men and dogs Electrogastrography was performed on the human subjects to determine the average hourly value of the amplitude and frequency of hungry contractions Accelerations were found to cause inhibition of the motor function of the stomach and alteration of the periodicity pattern The changes in the motor function appear to be secondary and to be associated with the changes in the functional state of the regulatory centers of motor activity B J A77-11372 # The effect of impact accelerations on the heart and hemodynamics of rats (Deistvie udarnykh peregruzok na serdtse i gemodmamiku krys) V I Gorlachev and A N Vizgalm Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, Jan-Feb 1976, p 3135 10 refs In Russian Drugged white rats were subjected to impact accelerations by dropping weights on their chest region, the accelerations thus acting in a spmeward direction, at a speed of 3 m/s The following measurements were made ECG,* blood pressure, blood volume, blood minute volume and electrolyte content in the blood plasma It was shown that impact on the cardiac area induced bradycardia, arrhythmia, ectopic beats, and atno-ventncular blockage followed by a drop in arterial pressure and a rise in venous pressure, and a decrease of cardiac output and blood volume The breakage of myocardial fibers was also noted B J A77-11377 # The time of adaptation of flying personnel to subtropical climates (O srokakh adaptatsu letno-tekhmcheskogo sostava k rabote v usloviiakh subtropicheskogo klimata) P G Kozacha and I R Grishin Kosmicheskaia Biologiia i Aviakosmi- cheskaia Meditsina, vol 10, Jan-Feb 1976, p 54-56 In Russian Sixty-eight flight crew members in the age range 24-50, arriving from the midlatitudes to the subtropics, were examined as to how long it took them to adapt to the subtropical climate The factors which served as an indication of acclimatization were sleep, appetite, mood, general state, heart rate, and arterial pressure It was found that acclimatization takes 2-4 weeks depending on the season The best season for adaptation is found to be spring-summer, when adaptation time is twice as short as in winter B J A77-11373 # The effect of centrifugal force on the neck nystagmus of pigeons (Vlname tsentrobezhnoi sily na shemyi nistagm u golubei) V A Kisliakov and L A Semenov Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, Jan -Feb. 1976, p 35-40 9 refs In Russian The paper reports on a quantitative investigation of the changes of the parameters of the nystagmus with respect to time and the modification of these parameters under the effect of otolith stimulation (centrifugal force) Pigeons were subjected to angular accelerations (positive and negative) which primarily affected the semicircular canals, to stimulation of the otolith organs by centrif- ugal force, and to angular acceleration of the labyrinth receptors Electromyography of the neck muscles was performed in conjunc- tion with the accelerations The centrifugal force is shown to have a dynamic effect on the nystagmus the modifications of the param- eters (latent period, frequency, time of minimum and maximum of frequency) of the nystagmus reveal phases of relaxed and severe response which depend, apparently, on the correlation of peripheral and central nervous processes, evoked simultaneously by the excita- tion of receptors of the semicircular canals and the vestibule B J A77-11374 # Dynamics of the motor components of the optokmetic nystagmus during exposure of the vestibular apparatus to angular accelerations (Omamika motornykh komponentov opto- kineticheskogo nistagma pri deistvu na vestibuliarnyi apparat uglo- vykh uskorenn) V I Babnak Kosmicheskaia Biologiia i Avia- kosmicheskaia Meditsina, vol 10, Jan-Feb 1976, p 40-45 10 refs In Russian A77-11378 ft Characteristics of the morphological responses of the viscera and endocrine glands of dogs subjected to gamma irradiation for 6 years (Osobennosti morfologicheskikh reaktsn vnutrenmkh organov i endokrmnykh zhelez sobak pri 6-letnem gamma-obluchenii) E A Savma, V I lakovleva, G I Plakhuta- Plakutma, and A S Pankova Kosmicheskaia Biologiia i Aviakosmi- cheskaia Meditsina, vol 10, Jan-Feb 1976, p 57-61 10 refs In Russian A77-11379 # The effect of the chronic action of small dosages of ionizing radiation on the excretion of gaseous metabolites among white rats (Vlname khromcheskogo deistvua malykh doz lomzirumshchei radiatsn na vydeleme gazoobraznykh produktov metabolizma u belykh krys) L A Tiunov, T S Kolosova, D T Lazurenko, and R S Apukhtina Kosmicheskaia Biologiia i Avia- kosmicheskaia Meditsina, vol 10, Jan-Feb 1976, p 61-66 19 refs In Russian A77-11380 H Development of reticulocytosis in the peri- pheral blood during exposure to a constant magnetic field (O razvitn retikulotsitoza v penfencheskoi krovi pri vozdeistvn postoiannogo magmtnogo polia) A G Borodkina Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, Jan-Feb 1976, p 66-70 10 refs In Russian Experiments were conducted to determine the effect of a constant magnetic field with a strength of 1000 0 on the 1 1 A77-11381 composition of the peripheral blood of test animals After exposure to the magnetic field, measurements were made of erythrocyte and reticulocyte content and hemoglobin level It was found that reticulocytosis develops, while the hemoglobin level and the eryth- rocyte count remains the same Continuous exposure to a constant magnetic field has provided evidence that animals can adapt to the effects of the magnetic field B J A77-11381 # The effects of hyperoxia and hypokinesia on the formation and excretion of gaseous metabolites among rats (Vliianie giperoksn i gipokmezii na obrazovame i vydeleme gazo- braznykh produktov zhiznedeiatel'nosti u krys) V V Kustov, B I Abidm, V I Belkin, and T A Lekareva Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Jan-Feb 1976, p 70-73 12 refs In Russian A77-11382 # A sorption method for the reclamation of water for the personal hygiene of cosmonauts (Sorbtsionnyi sbosob regeneratsii vody dlia lichnoi gigieny kosmonavtov) V B Gaida dymov, A G Prishchep, K V Zarubma, L E Balashova, and S P Tsareva Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Jan-Feb 1976, p 7375 In Russian The paper describes a sorption method for the reclamation of water to be used for the washing of face, hands, and bodies of cosmonauts in space Special attention is given to the selection and testing of a cleansing agent with bactericidal properties The agent chosen is Catamme-AB (alkyddimethylbenzylammonium chloride) and tests were performed on the agent to study its cleansinc properties and its effect on microorganisms The sorption methoc was developed on the basis of a study of the sorption ot Catamme-AB by a number of ion exchange resins and activatec charcoals B J A77-11383 ff An attempt to disrupt the diurnal periodicity of the excretion of potassium in the urine (Popytka 'rasshatyvamia' sutochnoi penodiki ekskretsii kalna s mochoi) S I Stepanova Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Jan-Feb 1976, p 76-86 5 refs In Russian Two men were isolated and subjected to 72 hours of continuous wakefulness in order to disrupt the circadian sleep-wakefulness cycle The aim of the experiment was to examine the feasibility of producing preliminary disruptions in the biorhythm which would prepare for adaptation to those experienced in space flight The index of disruption was to be the diurnal rhythm of excretion of potassium m the urine It was found that continuous wakefulness does not disrupt the diurnal periodicity of potassium excretion B J A77-11384 ff Determination of the adhesion properties of foodstuffs (Opredeleme adgezionnykh svoistv produktov pitanna) E M Rybalova and V P Babarm Kosmicheskaia Biologna i Avia- kosmicheskaia Meditsma, vol 10, Jan Feb 1976, p 8688 In Russian The paper discusses a way to eat rehydrated foodstuffs in space flight (weightless) conditions which allows one to use table utensils The method consists of using rehydrated foodstuffs with good properties of adhesion to the metal surfaces of the utensils An adhesiometer was used to measure the adhesion strength of a number of rehydrated foods which could be feasible for space consumption cottage cheese with nuts, cottage cheese with black currant puree, cottage cheese pudding, mashed potatoes, mashed potatoes with starch added, goulash, and chicken puree soup B J A77-11385 ff Electrospectroscopic method for evaluating the interaction of radiation with DNA molecules (Elektrospektro- skopicheskn metod otzenki vzaimodeistvna izluchenna s molekulami DNK) E A Shakunova, A D Chesnokov, and V D Chesnokova Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Jan-Feb 1976, p 89-91 7 refs In Russian The paper develops a quantum mechanical model for the interaction of radiation with DNA molecules assumed to have an energy band structure, and uses this model to construct an electrospectroscopic technique for investigating these interactions The frequency dependence of permittivity in the low frequency range gives information about the polarization of the double layer of DIMA molecules in a solution The appearance of additional potential on the surface of a molecule under the action of radiation quanta leads to a change in the parameters of low frequency permittivity Electrons which are excited by radiation quanta to higher energy levels, diffuse away from the irradiated surface into the layer, where they tunnel through the forbidden energy band of guanme and end up at the corresponding free energy levels of cytosme or adenme B J A77-11386 ,-, Current trends m biophysical studies of the vestibular function (Sovremennye napravlenna biofizicheskikh issle- dovann vestibuliarnoi funktsn) A A Shipov Kosmicheskaia Biolo- g/ia i Aviakosmicheskaia Meditsma, vol 10, Mar Apr 1976, p 8 16 122 refs In Russian Progress in the application of biophysical methods to experi mental and theoretical investigations of the vestibular function over the past ten years is reviewed Three maior trends are analyzed The first trend originates from Steinhauzen's discovery of elastic cupulae in the semicircular canals of the labyrinth and his hypothesis, where the cupulo endolymphatic system is considered as a supercntically damped torsional pendulum which can be described by a second order differential equation, subsequent studies determined the range of applicability of the Steinhauzen's model The second trend concentrates on particularities of stimuli of the vestibular system under natural conditions and in various moving systems Particular attention is given to the influence of Conolis forces on the endolymph of the semicircular canal in rotating systems (e g , space vehicles) The objective of the third trend is to describe the cooperation of the vestibular and oculomotor systems m stabilization of visual fixation Methods of the automatic control theory and the finite automaton approach are used to develop togico mathematical models of these functions Recommendations are presented for future research work along these hnes S N A77-11387 ,7 State of osseous tissue under conditions of hypokinesia and weightlessness, and the effect of thyrocalcitonin (Sostoianie kostnoi tkani v uslovnakh gipokmezii i nevesomosti i deistvie tirokal'tsitomna) A I Briskm, A I Volozhm, and V S Shashkov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Mar Apr 1976, p 1722 85 refs In Russian Extreme conditions of a space flight cause significant changes in the mineral salt metabolism of skeletal bones In particular, a reduction in the optical density of heel bone and spotted bone radiographs was observed in some astronauts It was shown that the effect of a long-time hypokinesia, connected with bed rest, motor paralysis, or application of plaster bandages to the inferior limbs, is similar to that of weightlessness Experimental studies on mineral metabolism disorders in bones during hypokinesia carried out over the last years are reviewed, with special attention to the role of thyroid gland hormones Experiments on animals revealed an antiresorptive effect of thyrocalcitonme (TCT), a preparation ob tamed from cattle thyroid gland, and its normalizing influence on Ca-metabohsm m bones and water salt metabolism during immobili zation and hypokinesia Research on the influence of TCT on man is to be done before using it for prophylaxis of metabolism disorders in bone tissues during hypokinesia S N A77-11388 ;t State of vascular regulation and regional hemo- dynamics in Soyuz-12 and Soyuz-13 crewmembers before and after flight (Sostoiante sosudistoi reguhatsn i regionarnoi gemodmamiki u chlenov ekipazhei 'Soiuz-12' i 'Soiuz-13' do i posle poleta) Kh Kh larullm, T D Vasil'eva, T N Krupma, D A Alekseev, and V F Turchanmova Kosmicheskaia Biologna i Aviakosmicheskaia Medi- tsina,\io\ 10, Mar-Apr 1976, p 2230 12 refs In Russian Postfhght rheographic examinations carried out at rest and during postural tests showed pronounced changes in the vascular 12 A77-11396 regulation and significant blood redistribution and vascular tone after flight On the landing day there were no signs of intracranical venous congestion during the antiorthostatic test This indicated a stable adaptation of cerebral circulation to weightlessness The tone of cerebral vessels, however, increased to prevent the development of cerebral venous congestion during the antiorthostatic test This may be a result of weightlessness adaptation The cerebral hemodynamic responses were more pronounced in the crewmembers who made an 8-day flight than in those who made a two-day flight, i e , in the cosmonauts who returned to earth after weightlessness adaptation (Author) A77-11389 „ Possible ways of solving the problem of 'biological compatibility' of crew members in long term space flights (O probleme 'biologicheskoi sovmestimosti' chlenov ekipazhei v dlitel'no deistvuiushchikh kosmicheskikh ob'ektakh i vozmozhnykh putiakh ee reshemia) lu G Nefedov, S N Zaloguev, and V P Savma Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Mar Apr 1976, p 3034 21 refs In Russian The notion of 'biological compatibility' involves a beneficial or adverse mutual influence of one individual on another as a result of release of trace amounts of chemicals and microorganisms into the environment Concentration of various chemical substances in expired air and the chemical composition of the latter was found to vary over a wide range from one individual to another, as well as chemical composition of sweat and volatile components released from the skin surface Response of the organism to the environment generated by another individual ('stranger') during his long term stay in a hermetic chamber is discussed It is assumed that the biological compatibility is based on individual differences in intensity and characteristics of biochemical processes The role and possible mechanisms of exchange of microorganisms are considered, along with the possibility of 'adoption' of another's microorganisms Experimental data suggest that man's microflore is specifically individual and that such an adoption is difficult and can be only relative Major trends of future research are outlined S N A77 11390 , Conditioning of water regenerated from water containing wastes (Konditsiomrovame vody, regenenrovannoi iz vlagosoderzhashchikh otkhodov) T I Luzina, N A Golikova, and M I Shikina Kosmicheskaia Biologna i Aviakosmicheskaia Medi tsma,vo\ 10, Mar Apr 1976, p 35-37 5 refs In Russian The problem of conditioning of water regenerated from wastes to obtain adequate potable water for space crews involves its enrichment in salts and its disinfection Extensive experiments on a large variety of natural minerals containing necessary macroelements and microelements were carried out to study the characteristics of water filtered through a layer of these minerals A composite filter consisting of silver coated dolomite and fluonte granules for simulta neous mineralization and disinfection of regenerated water is proposed Results of hygienic tests of water conditioned by using this filter are presented showing that the water is of full biological value S N A7711391 It A model of the physiological thermoregulation system (Model' fiziologicheskoi sistemy termoreguliatsii) lu A Rostopshm Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Mar-Apr 1976, p 37-41 10 refs In Russian A mathematical model of an isolated physiological thermo regulation system allowing for self-oscillations of the body tempera ture in homoiothermal animals is developed The conceptual basis of the model is connected with the notions of homeokmesis and noncontractile thermogenesis The rate of the ATP synthesis is assumed to control the heat production process An analysis of the obtained solutions reveals the existence of two steady-state regimes a state of rest and a self oscillation regime The period of self oscillations is supposed to be fully determined by the parameters of the heat emission system, while the amplitude of the phase variable depends only on biochemical processes S N A77 11392 •/ Study of in flight working capability of pilots during simulated motion sickness (Issledovanie letnoi rabotospo- sobnosti pilotov pri modelirovann bolezni dvizhenna) N A Razso- lov and O P lakovlev Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Mar Apr 1976, p 41-45 13 refs In Russian Using a modified procedure of taking cockpit instrument readings (color slides of the AN-24 aircraft instrument panel), the working capability of pilots was quantitatively studied under conditions of simulated bumpmess A point scale was developed to assess the results of the reading The minimum exposure for successful reading was found to be 4 sec for experienced pilots After five double rotation procedures statokmetically stable pilots devel- oped a latent form of motion sickness which manifested itself in decreased professional performance, while statokmetically unstable pilots showed pronounced symptoms of motion sickness in overt form The method can be used for medical examination of pilots' in flight reliability SN A77 11393 ft Influence of hyperoxia on the characteristics of external respiration, cardiovascular system, and gas composition of blood (Vlnanie giperoksu na pokazateli vneshnego dykhanna, serdechno-sosudistoi sistemy i gazovyi sostav krovi) O V Korku- shko and L A Ivanov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Mar-Apr 1976, p 45-50 20 refs In Russian A77-11394 n Evaluation of the rate of acoustic reception of radiotelegraph signals in psychological selection of candidates for pilot training (Ob issledovann skorosti pnema radiotelegrafnykh signalov na slukh v protsesse psikhologicheskogo otbora kandidatov dlia letnogo obuchenna) D I Shpachenko Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Mar Apr 1976, p 54 58 6 refs In Russian A77-11395 # Results of exposure of mammalian cell cul- tures aboard an earth satellite (Rezul'taty eksponirovanua kul'tury kletok mlekopitaiushchikh na iskusstvennom sputmke zemli) F V Sushkov, V V Portugalov, S V Rudneva, N N Bobkova, E K lordanishvih, and E A Izupak Kosmicheskaia Biologna i Aviakosmi- cheskaia Meditsma, vol 10, Mar Apr 1976, p 58-63 17 refs In Russian The paper presents the results of an exposure of cells of the Syrian hamster strain VNK 21 to space flight effects In contrast to the cell culture kept in a thermostat at 29 C, the cell culture that was maintained in thermally uncontrolled conditions developed notice- able structural and physiological changes induced by suboptimal temperatures It is concluded that a 6 day exposure to weightlessness has no pernicious effect on mammalian cells in vitro and produced no stable structural or physiological changes Some changes detected in the cell culture faster aging during flight, stable tendency to increased number of cells with enlarged nuclei, an increase in the mitotic index at an early stage of cultivation need further verification (Author) A77-11396 // The effect of a long-time influence of a constant and alternating 1000-oersted magnetic field on mitotic activity (O vlnann dlitel'nogo vozdeistvna postoiannogo I znako- peremennogo magmtnogo poll a 1000 e na mitoticheskuiu aktiv- nost') A D Strzhizhovskii and G V Galaktionova Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Mar-Apr 1976, p 63-67 6 refs In Russian Application of magnetic protection against ionizing radiation in long-term space flights will expose astronauts to the influence of low-gradient constant magnetic fields In order to assess their effect on the health and working capability, experiments on mice were earned out, in which the animals were exposed for 15 days to the influence of a 1000 oersted magnetic field of constant and changing direction The epithelium of the cornea and the bone marrow of the tested animals were subjected to a cytogenetic analysis No major disorder was observed An initial decrease in the mitotic index of the corneal epithelium and bone marrow was subsequently compensated 13 A77-11397 by adaptive mechanisms The developing mitotic hyperactivity results in an increased resistivity of tissues to some adverse factors (e g , ionizing radiation) The amount of cells in the tissues decreased insignificantly and rapidly returned to the normal value after switching off the field Changes in the field direction with respect to the position of the animal's body caused no additional reduction in mitotic activity, however, the efficiency of the adaptive processes drastically decreased S N A77-11397 !j Response of the fibroblasts of granulation tissue in regenerating skin to chronical hypoxia (Reaktsua fibro- blastov granuliatsionnoi tkani regenenruiushchei kozhi na khroni- cheskuiu gipoksnu) G V Khomullo, T V Ivanenko, and A N Chermaev Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Mar-Apr 1976, p 68-72 23 refs In Russian A77-11398 # Clmicophysiological studies of pilots with first stage hypertension (Klimko-fiziologicheskie issledovanna u letnogo sostava s gipertonicheskoi bolezn'iu I stadii) S N Akimov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsina, vol 10, Mar-Apr 1976, p 72-77 23 refs In Russian An examination of the functional state of the cardiovascular system based on hemodynamic and polycardiographic characteristics was carried out for a group of pilots suffering from first stage hypertensive disease, and the data obtained were compared with corresponding data for 40 healthy pilots The parameters reflecting the increase in the blood volume ejected into the blood stream were found to be the most informative In particular, the stroke volume, cardiac output, volume rate of the ejection, power of the left ventricle, energy expenditure per one liter of the cardiac output, and the time of the isometric contraction phase were found to increase m all examined subjects Interrelations between the cardiac output and the penphenc resistance allowed to identify three hemodynamic varieties of hypertension cardiac type characterized by an increase in the minute blood output (15 persons), vascular type with an increase in the penphenc resistance (11 persons), and mixed type, involving an increase in both parameters (4 persons)' Methods of treating are recommended for each of these varieties S N A77-11399 # Ultrasonic Doppler cardiography in the medical control system (Ul'trazvukovaia Doppler-kardiografiia v sisteme meditsmskogo kontrolia) A N Kozlov, V A Degtiarev, V S Bednenko, and V S Markov Kosmicheskaia Biologna i Aviakos- micheskaia Meditsina, vol 10, Mar-Apr 1976, p 77-81 13 refs In Russian A total of 550 ultrasonic Doppler cardiograms (USDC) of 43 healthy pilots were recorded to obtain normative USDC character istics, which should permit an adequate interpretation of cardiograms in medical control The method of analyzing USDCs is described Typical USDC signal components related to various cardiac cycle phases in healthy persons are presented for major location points of the heart Numerical results of phase analysis of the cardiac cycle and spectral analysis of the cardiograms, characterizing elasticity and motion velocities of cardiac elements in various zones of the heart, are discussed The low level of variations in velocities for different zones proved the possibility of a nonsearch heart location over a comparatively wide range The elasticity characteristics showed that the level of the reflected signal depends primarily on the energetic contribution from the cardiac walls S N bipolar method of impedance pneumography Noise stability and informativity were compared for two techniques impedance pneu- mography from a rheopneumogram (RPG), and pneumography with a strain gage from a penmetrogram (PG), with a spirogram (SpG) used as a reference technique It is shown that neither PG nor the RPG permit accurate data on respiratory volumes to be obtained The degree of correlation between RPG and SpG was found, however, substantially higher than that between PG and SpG The noise stability of both methods was evaluated by calculating the frequency of respiration during physical exercises and reading Both methods exhibited a low noise stability to physical exercises (that of RPG being slightly higher), while the RPG method showed a high noise stability to reading Change in respiration depth considerably influenced the amplitude of RPG curves but had little effect on PG curves The second set of experiments concentrated on the correla- tions between the RPG amplitudes and respiratory frequency and depth It was shown that using the RPG method, it is possible to obtain data not only on respiratory frequency and rhythm, as with PG, but also on the respiratory depth S N A77-11401 # Possibility of prolonged stay in water by means of a 'dry' immersion method (Vozmozhnost' provedenna dlitel'noi vodnoi immersii metodom 'sukhogo' pogruzhenna) E B Shul'zhenko and I F Vil'-Vil'iams Kosmicheskaia Biologna i Aviakosmicheskaia Meditsina. vol 10, Mar Apr 1976, p 82-84 5 refs In Russian A technique is developed for a long-duration experiment of 'dry' immersion of a man into water in order to simulate some effects of weightlessness and hypokmesia Human subjects placed in an ample high-elasticity waterproof cloth fixed to the boards of a special water bath (water temperature about 34 deg C) are immersed into water, in lying position, without using any other support Experiments employing this technique were carried out on 14 subjects for 13 days, and on 2 subjects for 56 days, using standard methods of continuous medical control during the whole period of the experi- ment The technique of 'dry' immersion permits to obtain physio- logical information from any part of the body No adverse effect of the immersion conditions on the subjects was observed S N A77-11402 ft Antitissular antibodies and complement in hypokmesia (Protivotkanevye antitela i komplement pri gipokmezn) V V Portugalov, A A Ivanov, and V IM Shvets Kosmicheskaia Biologna i Aviakosmicheskaia Meditsina, vol 10, Mar-Apr 1976, p 84-86 11 refs In Russian Long-time hypokmesia leads to the development of distrophy in striated muscles, the same process occurs during myasthema, a disease having an autoimmune component in its pathogenesis An attempt is made to find out the role of autoimmune mechanisms in the pathogenesis of myodistrophy during hypokmesia, with auto- antibodies and complement selected as indices of the possible autoimmunizing effect of hypokmesia Male mongrel white rats were kept under conditions of hypokmesia Their total weight showed a decrease of down to 74% on the 7th day, 87% on the 15th day, 73% on the 30th day, and 65% on the 60th day of the experiment, as compared to the weight of a reference group of animals An immunologic blood analysis showed a drastic increase in complemen- tal activity of the blood serum during the whole observation period A decreased level of antitissular antibodies was observed from the 7th to the 15th day, whereas during the period of 30th to 60th day this level increased drastically The second period was found to coincide with that of an increased frequency of finding agglutinm antibodies to ram erythrocytes A mechanism explaining the ob- served phenomena is tentatively proposed S N A77-11400 # Results of an impedance pneumography study (Rezul'taty issledovami impedansnoi pnevmografn) V G Savel'eva Kosmicheskaia Biologna i Aviakosmicheskaia Meditsina, vol 10, Mar Apr 1976, p 81, 82 In Russian The possibility of obtaining numerical characteristics of respira- tory volumes was studied in two sets of experiments using the A77-11403 # Change in state characteristics of the para- sympathetic nervous system during hypokmesia in rabbits (Ob izmenemi pokazatelei sostoianna parasimpaticheskoi nervnoi sistemy pri gipokmezn u krolikov) G D Reushkma Kosmicheskaia Biologna i Aviakosmicheskaia Meditsina, vol 10, Mar-Apr 1976, p 86-88 37 refs In Russian 14 A77-11411 A77-11404 tt On the expert diagnostic value of physiological parameters for objective monitoring of a pilot's condition in flight (Ob ekspertno-diagnosticheskoi tsennosti fiziologicheskikh para- metrov ob'ektivnogo kontrolia sostoianna letchika v polete) I D Malinin Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, May-June 1976, p 3-8 37 refs In Russian Effective methods are examined for expert diagnosis of a variety of pathological conditions arising during the action of unfavorable flight factors on pilots Selection of the necessary physiological parameters for pilot evaluation should provide solutions to three key diagnostic problems Ascertainment of sudden death during flight, diagnosis of acute diseases with disordered consciousness and reduced working capacity, and determination of hazardous changes in the psychic state of a pilot The information collected by relevant parameters is discussed These parameters include the heart rate, EKG, EMG, arterial blood pressure, and photoplethysmogram of vascular flow in ear lobule and skin Other parameters comprise body and skin temperature, pneumatachogram and changes in the rib cage perimeter, pulmonary ventilation, EOG, EEC, and GSR Aviation medicine should rely on computer-aided data processing for a rapid and reliable diagnosis of pilots SD leg and increased in the other leg During the descent, changes in the amplitudes of the response proved to be just the opposite The decrease in the H-response was correlated with oxygen deficiency of nerve afferents, while an increase was correlated with a supraspmal effect B J A77-11408 # Prevention of decompression sickness as relat- ed to repeated extravehicular activities (Profilaktika dekcmpression- noi bolezm primenitel'no k usloviiam mnogokratnykh vykhodov v kosmos) I N Cherniakov, V A Glazkova, and I V Maksimov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, May-June 1976, p 23-26 11 refs In Russian Six 3-day experiments were carried out on 6 subjects in an altitude chamber The experiments simulated repeated extravehicular activities i e intensive work at an altitude of 10,000 m in a helmet or at an altitude of 40,000 m in a space suit pressurized at 200 mm Hg It was demonstrated that altitude decompression could be prevented by desaturation consisting of prolonged exposure to the hypobanc atmosphere (430 mm Hg) and 100% 0 or a 40% 02 and 60% N2 mixture During the 3-day experiment the subjects made seven 3-4 hour excursions, showing no symptoms of decompression sickness (Author) A77-11405 H Rat experiment on a 22-day flight on the biosatellite Cosmos 605 /Objectives and methods/ (Ekspenment s krysami v 22-sutochnom polete na biologicheskom sputnike 'Kosmos-605'/Zadachi i metody/) E A ll'm. L V Serova.andA D Noskin Kosmicheskaia Biologna i Aviakosmicheskaia Meaitsma, vol 10, May-June 1976, p 9 14 In Russian In the 1974 experiment onboard the Cosmos 605 satellite Wistar rats were put in cages equipped with a feeder, water supply, light source, and ventilation device The principal objective of the experiment was to study the effects of 22 days of weightlessness and the subsequent period of readaptation to earth's gravity on the morphological and functional characteristics of the rat's physiology A series of postfhght clinical, physiological, morphological, cytologi cal, and biochemical studies were performed on the rats Tissue examinations were also conducted and remote aftereffects were studied B J A77-11406 n Activity of DMA depolymerases in the rat spleen after flight aboard the Cosmos 605 satellite (Aktivnost' depohmeraz DNK v selezenke krys posle poleta na sputnike 'Kosmos-605') V F Makeeva, G S Komolova, L V Serova, E V Behkova, and I A Egorov Kosmicheskaia Biologna i Aviakosmi- cheskaia Meditsma, vol 10, May-June 1976, p 1417 14 refs In Russian The activity of enzymes involved m DMA disintegration (acid and alkaline DNA-ases) was measured in the spleen of rats onboard the Cosmos 605 satellite for 22 days The activity of alkaline DIMA ase remained unaltered, whereas that of acid DNA ase increased more than twice The activity of acid DNA-ase returned to the normal postfhght day Analysis of the characteristic viscosity of native and denatured DIMA showed that enzyme activation was not followed by degradation changes in the DNA molecule (Author) A77-11407 H Changes in the monosynaptic H-response of man during altitude decompression (Izmenemia monosmapti cheskogo H-refleksa pri vysotnoi dekompressn u liudei) L V Kaliuzhnyi and I N Zakharova Kosmicheskaia Biologna i Aviakos- micheskaia Meditsma, vol 10, May June 1976, p 1722 17 refs In Russian Fifteen subjects were tested for altitude decompression dis orders in a hypobanc chamber under the following simulated altitudes ascent from sea level to a height of 11,000 m, descent to 3000 m, and repeated ascents from 3000 m to 7000 10.000 m The key feature of the test was the neuroelectrical H response of the leg muscles correlated with the decompression disorders When bends developed in a leg, the amplitude of the H-response decreased in that A77-11409 # State of the human motor system during exposure for many days to a nitrogen-oxygen environment at pressures of up to 5 atm (O sostoiann dvigatel'nogo apparata cheloveka v period mnogosutochnogo prebyvanna v azotno- kislovodnoi srede pri davlenn do 5 ata) R L Boush Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, May June 1976, p 26-31 18 refs In Russian The state of the motor function of individuals exercizing on a bicycle ergometer in an altitude chamber containing a nitrogen- oxygen environment at 5 0 atm was studied Maximum isometric force, precision of movement control and muscular tension, accuracy and velocity of movements were recorded The maximum force, precision and velocity of movements varied phasically The greatest changes were found on the 1st-3rd and 6th-7th days of the exposure These parameters returned to the normal when the atmosphere pressure was reduced to 1 0 atm During exercise at an elevated pressure, the muscular force, accuracy and velocity of movements decreased During exercise at a normal pressure, similar changes were less distinct and consistent (Author) A77-11410 # Adrenal function in man during exposure to a hyperbaric environment for many days /N2-O2, 5 atm/ (Funktsna nadpochechmkov pri mnogosutochnoi ekspozitsu cheloveka v uslovnakh giperbam /IM2-O2, 5 ata/) N M Turubmer Kosmi- cheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, May-June 1976, p 32-37 37 refs In Russian Human subjects were exposed to a nitrogen-oxygen environment at 5 atm, performing various activities The adrenal function of the subjects was examined for catecholamine and corticosteroid excre- tion in the urine During environmental adaptation, the excretion of catecholammes and corticosteroids varied phasically After 3 days of the 7-day exposure to the hyperbaric atmosphere and during decompression the exretion of norephmephrme increased and that of corticosteroids, particulary 17-corticosteroids, decreased The diurnal rhythm of the excretion changed in spite of the normal life regimen of the subjects These variations can be considered as adaptive- protective responses of the human body (Author) A77-11411 If Effect of body position relative to the gravity vector on water balance (Vlnanie na vodnyi obmen polozhenna tela otnositel'no vektora gravitatsn) V P Krotov and L L Romanov- ska i a Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, May-June 1976, p 37-41 20refs In Russian A combined effect of hypokmesia and body position at different angles to the gravity vector on the water content and rate of its metabolism was studied It was shown that bed rest reduced 15 A77-11412 total water losses and the rate of its metabolism It was body position relative to the gravity vector rather than bed rest that influenced the total water content in the body (Author) A77-11412 # Recovery of muscular functions in rats after prolonged hypokmesia (Vosstanovleme funktsn myshts u krys posle dlitel'nogo ogramchemia podvizhnosti) V S Oganov, A N Potapov, G S Katinas, and M P Skoroghadova Kosmicheskaia Biologua i Aviakosmicheskaia Med/tsma, vol 10, May June 1976, p 41-47 14 refs In Russian Experiments were conducted to measure the recovery dynamics (time and force parameters) of the isometric contractions and morphological characteristics of the hind limb muscles of white rats kept in prolonged hypokmesia for 130 days and then under surveillance for 3 months The soleus muscle was found to display changes indicative of atrophy, while the ext digit longus and platans muscles showed recovery of force parameters The latter muscles also displayed delayed contraction due to an increase in the time of tension development and semirelaxation B J A77-11413 ft Hemopoietic organs of mice during hypoki- nesis (Organy krovetvorenna myshei pri gipokinezn) V N Shvets and N P Krivenkova Kosmicheskaia Biologua i Aviakosmicheskaia Meditsma, vol 10, May June 1976, p 47-53 12 refs In Russian Experiments were performed on inbred male mice to study the capacity of hemopoietic cells for colony formation and the pattern of their differentiation during hypokmesia Lymphoid organs were weighed, hemopoietic cells were counted, and blood smears were prepared by standard methods The colony forming properties and the differentiation capacity of the hemopoietic cells of the spleen and bone marrow were studied using a method of in vivo culturing and gamma irradiation The differentiation capacity of colony forming units from the spleen and bone marrow were not altered toward erythro-, myelo-, and thrombo-poiesis B J A77-11414 .... Some principles for the recovery of central vision after temporary blindness (Nekotorye zakonomernosti vos- stanovlenna tsentral'nogo zrenua posle vremennogo osleplenna) V I Kartsev and N K Luk'ianov Kosmicheskaia Biologua i Aviakosmi- cheskaia Meditsma, vol 10, May-June 1976, p 53-58 17 refs In Russian Forty healthy subjects were tested in an effort to determine the mechanisms of the recovery of central vision after temporary blindness experienced by pilots and astronauts due to prolonged light adaptation The experiments consisted of two steps light adaptation produced in a definite time interval by a white screen illuminated by the sun or an incandescent lamp, and a study of the recovery of visual acuity in the range 01-05 under conditions of dark adaptation after the lamp is turned off It is shown that the recovery time increased exponentially with an increase in stimulating light intensi- ty B J A77-11415 ft Dependence of human body weight loss on space flight duration (Zavisimost' poteri vesa cheloveka ot prodolzhi- tel'nosti kosmicheskogo poleta) V V Verigo Kosmicheskaia Biolo- gua i Aviakosmicheskaia Meditsma, vol 10, May-June 1976, p 58-61 In Russian A formula is proposed for determining weight losses in the first approximation during a space mission, assuming that humans may adapt to space flight effects The process depended on two parameters for maximum body weight loss and adaptation time Weight estimates of Skylab crewmembers obtained by the formula are found to be in good agreement with actual results The typical adaptation time was two days Possible ways of constructing a more precise model of weight changes and its use to predict the condition of crewmembers are discussed (Author) A77-11416 ff Comparative characterization of electro- cardiograms in flight personnel with normal and excessive weight under moderate hypoxia (Sravmtel'naia kharaktenstika elektro- kardiogramm u letnogo sostava s izbytochnym i normal'nym vesom tela v uslovnakh umerennoi gipoksn) I R Grishm, P G Kozacha, and L A Stefanov Kosmicheskaia Biologua i Aviakosmicheskaia Meditsma, vol 10, May-June 1976, p 61-64 In Russian A77-11417 -' Methods for studying the tolerance of pilots to inflight acceleration (Metodika issledovamia perenosimosti letchikom peregruzok v uslovnakh poleta) P M Suvorov, V I Babushkm, and D lu Arkhangel'skii Kosmicheskaia Biologua i Aviakosmicheskaia Meditsma, vol 10, May-June 1976, p 64-67 In Russian Experiments were performed in a specially equipped aircraft with dual control to study pilot tolerance to inflight acceleration, consisting of three dives, attaining levels of 3 0, 5 0, and 6 0 g for 30 s at intervals of 1-2 mm and an onset rate of 0 4-0 6 g/s The onboard monitoring equipment consisted of an ECG, an ear pulse rate recorder and a motion picture camera for cinematography of the pilot's face during exposure to acceleration The most interesting result was a sharp decrease of the pulse rate in the blood vessels of the ear (25% and more below the base level) accompanied in 80% of the cases by visual disorders B J A77-11418 it Evaluation and application of the quantitative indices of the quality of operator work (Otsenka i primeneme kohchestvennykh pokazatelei kachestva raboty operatorov) V V Lebedev and V A Krutov Kosmicheskaia Biologua i Aviakosmi cheskaia Meditsma, vol 10, May June 1976, p 68 71 In Russian The paper describes a method for determining quantitative indices of the quality of the performance of operators involved in spacecraft control Quality indices are calculated from statistical data obtained from flights and flight simulation experiments A general scheme for evaluating quality indices is presented consisting of the following steps collection of data of the quality of operator performance during flight and training, data processing and calcula tion of the statistical characteristics of performance quality, the establishment of constraints on performance quality parameters, and the calculation of quality indices These indices are applied to the following tasks spacecraft design, flight plan development, operator training, and operator control of spacecraft B J A77-11419 # Investigation of the biological properties of type-A Cl perfrmgens released in persons placed in a hermetic chamber (Issledovame biologicheskikh svoistv Cl perfrmgens tipa A, vydelennykh u liudei v uslovnakh prebyvamia ikh v germeticheskoi kamere) V M Shilov, E P Zemhamtskaia, and O K Bonsbva Kosmicheskaia Biologua i Aviakosmicheskaia Meditsma, vol 10, May-June 1976, p 71-75 23 refs In Russian * A77-11420 # Coronary vessels of the rabbit following single irradiation of the heart area with a dose of 2400 rad (Koronarnye sosudy krolika posle odnokratnogo obluchenna oblasti serdtsa v doze 2400 rad) A I Vorob'ev and L A lakovleva Kosmicheskaia Biologua i Aviakosmicheskaia Meditsma, vol 10, May June 1976, p 75-77 In Russian A77-11421 ij Evaluation of the state of the cardiovascular systems of helicopter flightcrews (Otsenka sostoianna serdechno- sosudistoi sistemy u ekipazhei vertoletov) L V Chireikm, E V Bondarev, V A Egorov, V A Kolosov, and B P Bataev Kosmicheskaia Biologua i Aviakosmicheskaia Meditsma, vol 10, May-June 1976, p 78, 79 In Russian Vanational ECG pulsometry was used to study the heart rhythms of 33 healthy helicopter flight crew members in the age 16 A77-11433 range 20-40 years Vanational pulsograms were constructed on the basis of RR intervals of 005 s, and the following values were considered during analysis of the variability of the dynamic series of intervals the difference between the maximum and minimum values of RR, the mean value of RR. the root-mean-square deviation, the mode, the asymmetry measure, and the coefficient of variation The major results were a quickening of heart rate for most of the crew members in horizontal flight, evidence for sympathicotonic responses during flight, observed bradycardia for most of the crew members after flight BJ A77-11422 d Effect of alpha radiation on Chlorella vulgaris at different stages of cellular cycle (Deistvie alpha-izluchenna na raznye stadn kletochnogo tsikla khlorelly) L K Vekshma, I S Sakovich, and V A Shevchenko Kosmicheskaia Biologiia i Aviakos- micheskaia Meditsina, vol 10, May June 1976, p 79, 80 5 refs In Russian A77-11423 •? Effect of caloric stimulation of the vestibular system on body temperature (Vlnanie kaloricheskogo razdrazhenna vestibuliarnogo apparata na temperaturu tela) I I Voinova and I M Emel'ianova Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, May-June 1976, p 81 In Russian A77-11424 # Effect of cupnc bromide on the intensity of release of gaseous substances from a waste disinfection facility (Vlnanie bromnoi medi na mtensivnost' vydelenua gazoobraznykh veshchestv iz assenizatsionnogo ustroistva) L T Poddubnaia and L N Rogatina Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, May June 1976, p 8183 8 refs In Russian A77-11425 if Characteristics of fatigue among people of different occupations (Kharaktenstika utomlenna u I its razlichnykh professn) E F Polezhaev and V A Epikhm Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, May-June 1976, p 83, 84 6 refs In Russian The characteristics of muscular fatigue of three groups of workers were studied operators whose function is characterized by insignificant levels of psychophysiological stress and by the absence of physical strain, production line workers whose work is character ized by monotony and physical strain, and automobile operators whose work is characterized by considerable psychological and neurophysiological stress and static strain Results show the existence of three stages of development of muscular fatigue a first stage characterized by an improvement of the indices of muscular endurance and visual motor performance, a second stage charac- terized by a stabilization and incipient decrease in these indices, and a third stage characterized by a sharp decrease in the indices B J A77-11426 # Direct simulation of a radiobiological survival experiment (Priamoe modelirovame radiobiologicheskogo ekspen- menta po vyzhivaemosti) R A Kuzin, V A Sakovich, V G Semenov, and V V lurgov Kosmicheskaia Biologiia i Aviakosmi- cheskaia Meditsina, vol 10, May June 1976, p 84-86 In Russian A direct computerized simulation using the method of statistical tests is used to determine the probability of survival of animals exposed to radiation Direct simulation consists of the uniform distribution of random numbers between 0 and 1 which correspond to the probability of the death of individual animals (under the given dosage to which it is subjected) The probability of death is determined from the hypothetical dependence of the radiation sensitivity of the individual animal on dosage If the random number is greater than this probability, the animal is supposed to be dead, and vice versa B J A77-11427 I! Functional state of the liver-pancreas system during exposure to low transverse accelerations (Funktsional'noe sostoiame gepato-pankreaticheskoi sistemy pri vozdeistvn malykh po velichine poperechno-napravlennykh uskorenu) K V Smirnov, L G Goland, and I L Medkova Kosmicheskaia Biologiia i Aviakosmi- cheskaia Meditsina, vol 10, May June 1976, p 86-88 8 refs in Russian A77-11428 H Effect of psychotropic drugs on some indices of the vestibular function (Vlnanie psikhotropnykh preparatov na nekotorye pokazateh vestibuharnoi funktsn) E F Lavretskaia, I I Voinova, and T P Privol'neva Kosmicheskaia Biologiia i Aviakosmi- cheskaia Meditsina, vol 10, May-June 1976, p 88, 89 13 refs In Russian A77-11429 ff Dynamics of changes in the galvanic skin response in man during altitude decompression (Dinamika izmenenna kozhno-gal'vamcheskoi reaktsii u liudei pri vysotnoi dekompressn) L V Kaliuzhnyi and N M Kirgizova Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, May-June 1976, p 90, 91 In Russian A77-11430 # Cellular and molecular aspects of adaptation (Kletochnye i molekuharnye aspekty adaptatsn) M G Tairbekov Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, July-Aug 1976, p 3-9 34 refs In Russian The paper generalizes available current hypotheses about the mechanism underlying the influence of detrimental factors of the environment on the structural and functional organization of the cell A discussion of findings pertaining to personal and other investigations suggests that the primary changes to be considered in adaptation are those occurring m cellular structures The material foundation upon which these changes take place is represented by the biological membranes, whose chemical composition and physical properties dictate the stability of cellular organoids and the cell as a whole The set of nonspecific changes occurring in the cell lead to complex adaptive responses above the cell and organ levels for an integrated adaptation of the organism S D A77-11432 # Some characteristics of the metabolism of proteins and ribonucleic acids in the central nervous system of rats in space flight aboard the Cosmos 605 satellite (Nekotorye kharak tenstiki metabohzma belkov i ribonuklemovykh kislot v tsentral'noi nervnoi sisteme krys, nakhodivshikhsia v kosmicheskom polete na sputnike 'Kosmos-605'l 0 G Gazenko, N N Demm, A N Panov, N L Rubmskaia, and R A Tigraman Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, JulyAug 1976 p 14-19 18 refs In Russian A77-11433 * Morphological effects in rats after a 22-day space flight (Morfologicheskie effekty u krys posle 22-sutochnogo kosmicheskogo poleta) V V Portugalov, E A Savina, A S Kaplanskn, V I lakovleva, G I Plakhuta-Plakutina, A S Pankova, E I Alekseev, P I Katuman, G N Durnova, and E I ll'ina- Kakueva Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina, vol 10, July-Aug 1976, p 1925 9 rofs In Russian A morphological examination of 27 rats aboard a satellite and sacrificed on the 1st 2nd and 26th-27th postflight days demonstrated no significant changes in the structural organization of the vital organs and systems of the animal body It was, however, found that the space exposure resulted in morphologically detectable changes in the musculo-skeletal system, hemopoiesis and lymphopoiesis, hypo- thalamic-pituitary-adrenal system and the juxtaglomerular apparatus of the kidneys The changes were reversible and nonspecific, and could be seen in animals in ground-based hypokmetic and other stress experiments After flight, the animals developed some re- sponses similar to those in humans The results help to identify the 17 A77-11434 morphological substrate of certain changes in the human body and investigate their pathogenesis (Author) A77-11434 # ' Effect of a 22-day space flight on the metab- olism of skeletal muscle tissue in rats (Vlnanie 22-sutochnogo kosmicheskogo poleta na metabolizm tkam skeletnykh myshts u krys) M S Gaevskaia, A S Ushakov, R A Belitskaia, N A Veresotskaia, T F Vlasova, E V Kolchma, N S Kolganova, L M Kurkma, E A Nosova, and N P Rassolova Kosmicheskaia Biologiia / Aviakosmicheskaia Medits/na, vol 10, July-Aug 1976, p 25-30 14 refs In Russian Skeletal muscles of rats having undergone a space flight showed no changes in the content of glycogen, adenosme tnphosphatase activity of myosin and protein content in protein fractions (except the T fraction where the protein content increased on the 1st day after landing and returned to the normal on the 26th postflight day) On the 1st postflight day, activities of ammotransferases and lactate dehydrogenase (LDH) of sarcoplasmatic proteins were elevated and the isoenzyme spectrum of LDH was changed as if in muscular atrophy The amount of free ammo acids in muscles was lowered On the 26th postflight day the enzymic activity of sarcoplasmatic proteins remained increased, whereas the isoenzyme spectrum of LDH returned to the normal and the amount of free ammo acids increased significantly In the microsomal fraction of muscles the phospholipid content decreased on the 1st day after landing and returned to the normal on the 26th postflight day (Author) A77-11435 ff Tolerance to +Gz acceleration of pilots with a tendency toward hypotensive responses under hot climate conditions (Perenosimost' uskorenn +Gz letchikami so sklonnost'iu k gipotom- cheskim reaktsnam v uslovnakh zharkogo klimata) S V Kolesmkov, R A Vartbaronov, and A R Kotovskaia Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsma, vol 10, July-Aug 1976, p 30-35 12 refs In Russian During acrobatic flying the acceleration tolerance of healthy and hypotensive pilots was studied under hot climate conditions From the professional viewpoint, the pilots were very similar The tolerance was determined on the basis of indirect indices derived from flight accelerograms (maximum and median acceleration values, number of peaks over 4 g, time of flying) The maximum value and the number of peaks of acceleration (+Gz) over 4 g can be recommended as practically indicative of the tolerance The observa- tions showed an adverse effect of initial hypotension occurring in hot climate on the acceleration tolerance As compared with the controls, the tolerance decrease in 12 hypotensive pilots was 1 1 g and 0 6 g of the maximum and median values, respectively (Author) A77-11436 # Some responses of man to prolonged centri- petal accelerations /+Gz/ of small values (Nekotorye reaktsu cheloveka na dhtel'nye tsentrostremitel'nye uskorenna /+Gz/ malykh vehchm) R R Galle, V V Usachev, L N Gavrilova, L G Elkma, P A Elkm, I S Knkun, V G Ovechkm, and 8 V Ustiushm Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsma, vol 10, July-Aug 1976, p 35-40 20 refs In Russian The effect of centripetal accelerations (+Gz) of low values (0 5-0 6 g) applied for four days against the background of relative hypokmesia was investigated The peripheral and mtracramal circula- tions, equilibrium function and morphological composition of the capillary blood were examined During the first three centnfugation days the hemodynamic state differed insignificantly from the initial level On the fourth day, signs of cardiovascular deconditionmg were observed by the orthostatic test Changes in the peripheral blood indicated a moderate stress-response which persisted throughout the entire experiment Equilibrium changes that were observed on the first centnfugation day regressed and the post-test function did not essentially differ from the initial level The experimental results show that inertia forces can be used to dimmish the detrimental effects of hypokmesia (Author) A77-11437 § Effect of systematic gravity exposures on external respiration during prolonged immersion (Vlnanie siste- maticheskikh gravitatsionnykh vozdeistvn na funktsnu vneshnego dykhanna v uslovnakh dlitel'noi immersu) lu N Kamenskn, E B Shul'zhenko, and V G Andreeva Kosmicheskaia Biologiia i Avia- kosmicheskaia Meditsma, vol 10, July-Aug 1976, p 40-45 29 refs In Russian Subjects were exposed to 13-day water immersion alone or combined with centnfugation The immersion did not influence the state of ventilation and gas exchange at rest, diminished significantly the functional capabilities of external respiration An exposure to acceleration during the second half of water immersion resulted in the normalization of the functional reserves of external respiration This may be the result of an increase in the total physical tone of the body (Author) A77-11438 # Human cardiovascular responses to orthostatic tests after highland adaptation (Reaktsna serdechno-sosudistoi sistemy cheloveka na ortostaz posle adaptatsn k vysokogor'iu) V S Georgievskn, V I Korol'kov, and V M Mikhailov Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsma, vol 10, July-Aug 1976, p 45-49 31 refs In Russian Orthostatic tolerance of 18 healthy test subjects (three groups of 6 persons each) who were exposed to an altitude of 2200 m for 12 days and 3200 m for 12 days was studied The first group subjects remained in bed with minimized motor activity The second group test subjects rested in bed and twice a day performed physical exercises with an energy expenditure of 300 kcal/day The third group subjects led a normal life It is shown that a prolonged restriction of motor activity and a decrease in the blood hydrostatic pressure of healthy test subjects in highlands result in diminished orthostatic tolerance Physical exercises prove ineffective in that case The subjects who led a normal life showed increase cardio- vascular responses to the orthostatic tests (Author) A77-11439 tl Quantitative evaluation of ultrastructural changes in the myocardium of the rat during prolonged hypokmesia (Kolichestvennaia otsenka ul'trastrukturnykh izmenenu v miokarde krys pn dlitel'noi gipokmezn) V S Romanov Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsma, vol 10, July-Aug 1976, p 50-54 35 refs In Russian Experiments were conducted to study and quantitatively assess the ultrastructural changes in the organoids of the myocardial cells in the right and left ventricles of the heart in restrained rats during a hypokmetic period of 120 days Morphometric analysis revealed that the redistribution of chromatm in the nuclei of myocardial cells was similar in the two ventricles of the rats The ratio of the total area of mitochondria to the total area of myofibnls varied periodically throughout the experiment, with increased area of mitochondria by the end of the 120th day Myocardial changes by the end of hypokmetic period are indicative of a new level of cardiac activity Quantitative changes in the myocardial organoids were more sigmfi cant in the left than m the right ventricle S D A77-11440 # Effect of nerobol on the fluid-electrolyte metabolism and function of kidneys in man during 120-day hypokmesia (Vlnanie nerobola na vodno-solevoi obmen i funktsnu pochek cheloveka pn 120-sutochnoi gipokmezn) A I Grigor'ev, Z P Pak, lu S Koloskova, G I Kozyrevskaia, M M Korotaev, and lu E Bezumova Kosmicheskaia Biologiia i Aviakosmicheskaia Me- ditsina.vo\ 10, July-Aug 1976, p 55-59 11 refs In Russian A77-11441 ff Diagnostic significance of free ammo acid content in the blood plasma during dietary protein deficiency m man (0 diagnosticheskoi znachimosti sodershanna svobodnykh amino- kislot v ptazme krovi pri ahmentarnoi belkovoi nedostatochnosti u cheloveka) V G Vysotskn, T F Vlasova, A S Ushakov, and T V Nevolma Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsma, vol 10, July-Aug 1976, p 59-64 27 refs In Russian 18 A77-11452 A77-11442 # Calonmetry of the human body in a hermetic enclosure (Kalorimetrna cheloveka y zamknutom germoob'eme) A A. Glushko, S M Gorodinsku, and B V Orekhov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, July-Aug 1976, p 64-69 9 refs In Russian Results are presented for an experimental evaluation of a biocalonmeter carried on the body and a heat-measuring suit Theoretical concepts are outlined underlying direct calonmetry of a suited man, along with a block diagram of the biocalonmeter used to examine the energy parameters of the human body, including metabolic rate, heat production, heat release and heat balance The data obtained were statistically treated and heat effects were characterized by empiric expressions It was for the first time that the personal calorimeter and calonmetric suit made it possible to collect information on the thermal state of the human body This information helps to diagnose the health condition of man and to standardize environmental parameters in aviation and space suits (Author) A77 11443 # Investigation of the biological effect of vibra tion on plants (Izuchenie biologicheskogo deistvua vibratsii na rastennakh) J A Fischere and lu I Shaidorov Kosmicheskaia Bio/ogna i Aviakosmicheskaia Meditsina, vol 10, JulyAug 1976, p 69-72 12 refs In Russian Results are presented for an experimental study designed to assess the biological impact of vibration on lettuce seeds and sprouts grown at optimal (20 C) and suboptimal (4 C) temperatures It is shown that the effectiveness of vibration is little dependent on its frequency (500-2000 Hz), but the sensitivity of the plants to vibration depends on their physiological condition The disorders caused by vibration are of temporary character, i e , processes in the plants return to the normal in a relatively short time S D A77-11444 # Search for a urine preservative as related to the oxidative-catalytic method of water regeneration (Izyskame konser vanta mochi primenitel'no k okislitel'no-kataliticheskomu metodu regeneratsn vody) A G Prishchep and V B Gaidadymov Kosmi- cheskaia Biologna i Aviakosmicheskaia Meditsina, vol 10, July Aug 1976, p 73-75 5refs In Russian! Experiments were conducted for a comparative evaluation of various chemical compounds as urine preservatives in regenerative water supply systems in manned spacecraft The urine preservatives discussed were formalin, sodium metabisulfite, sorbic acid, para oxybenzoic acid, 9oxyqumohne, Catamme AB, Catapm 8300, chloramme, mono-Chlorantme, and sulfo-Chlorantme Analysis of microbicidal activity and quality of regenerated water revealed that 01% formalin appears to be the best compound for conserving urine for more than 3 months S D A77-11445 # Hegglm's syndrome in flight personnel with atherosclerotic coronary cardiosclerosis and its dmical evaluation (Sindrom Khegglma u (its letnogo sostava s ateroskleroticheskim koronarokardiosklerozom i ego klinicheskaia otsenka) V M Kon drakov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsina, vol 10, July-Aug 1976, p 7578 9 refs In Russian A77-11446 H Combined effect of hypokmesis and elevated oxygen content on animal resistance to carbon monoxide (Kom pleksnoe vozdeistvie gipokmezii i povyshennogo soderzhanua kislo roda na ustoichivost' zhivotnykh k okisi ugleroda) B I Abidm, V I Belkin, and V V Kustov Kosmicheskaia Biologita i Aviakosmi cheskaia Meditsina, vol 10, July-Aug 1976, p 79,80 In Russian A77-11447 n Effect of psychophysiological self adjustment on flight training (Vlname psikhofiziologicheskoi samoreguhatsn na protsess letnogo obuchenna) D I Shpachenko and K I Mirovskii Kosmicheskaia Biologna i Aviakosmicheskaia Meditsina, vol 10, JulyAug 1976, p 81,82 In Russian A77-11448 ,7 Study of subjective evaluations of the normal state of operators in a long-term tracking procedure (Izuchenie sub'ekttvnykh otsenok sobstvennogo sostoianna operatorov v pro- tsesse dlitel'nogo slezhenna) B P Shestkov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsina, vol 10, July-Aug 1976, p 82 84 In Russian A77-11449 !,' Physicochemical purification of the gas-vapor phase formed during dessication of solid waste from human vital activity (Fiziko-khimicheskaia ochistka parogazovoi fazy, obrazuiu- shcheisia pn sushke tverdykh otkhodov zhiznedeiatel'nosti che- loveka) G S Siniak, L V Dagaeva, lu V Pepehaev, N V Kel'tsev, L la Margolis, and B G Gusarov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsina, vol 10, July-Aug 1976, p 8486 7 refs In Russian A77-11450 n Preliminary results of medical studies during the flight of the second expedition of the Salyut 4 orbital station (Predvantel'nye rezul'taty meditsmskikh issledovann, vypolnennykh vo vremia poleta vtoroi ekspeditsii orbital'noi stantsn'Saliut-4') E I Vorob'ev, 0 G Gazenko, N N Gurovskn, lu G Nefedov, B B Egorov, R M Baevskn, I I Brianov, A M Genm, V A Degtiarev, and A D Egorov Kosmicheskaia Biologna I Aviakosmicheskaia Meditsina, vol 10, Sept-Oct 1976, p 3-18 In Russian The paper discusses the program and results of medical investigations concerning the 63-day stay of crewmembers aboard the Salyut 4 orbital station Attention is focused on the responses of the cardiovascular system to weightlessness Other areas discussed include the vestibular analyzer, external respiration, metabolism, blood perfusion of the brain, and other related topics During space flight, the human body is found to adapt to the new environment through a period of adaptive readjustment and a period of relative stabilization, the latter being generally reached after 1 5 months of exposure to weightlessness No substantial physiological changes are observed which would prevent further planned increases in the duration of future space missions S D A77-11451 K Orthostatic tolerance of cosmonauts after 30- and 63-day flights onboard the orbital base Salyut-4 (Ortostati- cheskaia ustoichivost' u kosmonavtov posle 30- i 63-sutochnykh poletov na orbital'noi stantsn 'Saliut-4') V V Kalinichenko, B F Asiamolov, and A F Zhernavkov Kosmicheskaia Biologna i Avia- kosmicheskaia Meditsina, vol 10, Sept-Oct 1976, p 18-23 9 refs In Russian Reactions of the circulation system of cosmonauts to inclina- tions in the head-up and head down positions were studied after a 30-day and a 63-day flight All the four cosmonauts showed a decline in orthostatic tolerance An improved system of countermeasures against the unfavorable effects of weightlessness, used during the 63-day flight helped to maintain a better orthostatic tolerance of the crew members than during the 30-day flight It is assumed that a rapid improvement in orthostatic tolerance after flights indicates an adequate maintenance of functional capabilities of circulation and suggests possible stimulation of its antigravity mechanisms prior to reentry in order to prevent postflight orthostatic disorders An exposure to weightlessness increased the capacity of circulation to counteract the blood redistribution in the cranial direction in the head-down position This capacity became more pronounced and stable with increasing flight time (Author) A77-11452 If Cardiorespiratory responses of cosmonauts to graded physical work after 30- and 63-day flights aboard the orbital base Salyut-4 (Reaktsu kardio-respiratornoi sistemy na dozirovan- nuiu fizicheskuiu nagruzku u kosmonavtov posle 30-1 63-sutochnykh poletov na orbital'noi stantsn 'Saliut-4') A V Beregovkm, A S Vedolazov, V S Georgievskn, V V Kalinichenko, N V Korelm, V M Mikhailov, lu D Pometov, V V Shchigolev, and B S Katkovskn Kosmicheskaia Biologna i Aviakosmicheskaia Meditsina, vol 10, Sept-Oct 1976, p 24-29 11 refs In Russian Cardiorespiratory responses of Salyut-4 crew members to 19 A77-11453 exercises (600 kgm/min for 7 mm) on a bicycle ergometer in the supine position were studied. It was found that the 30- and 63-day flights induced a certain decrease in the response of the organisms resulting in a less economic functioning of the cardiorespiratory system during exercises The degree of postflight changes in the 30- and 63-day crew members was alike At the same time the cardiorespiratory system of the 63-day crew members returned to the prefhght level more rapidly than that of the 30-day cosmonauts (Author) A77-11453 ff Theoretical aspects of the problem of predict- ing the state of the human organism during space flight (Teoreticheskie aspekty problemy prognozirovanna sostoianna or- ganizma cheloveka vo vremia kosmicheskogo poleta) lu M Svi- rezhev, N I Vikhrov, and V V Verigo Kosmicheskaia Biologua i Aviakosmicheskaia Meditsina, vol 10, Sept Oct 1976, p 30-37 In Russian The general principles are examined of the application of mathematical methods to the development of systems for predicting the state of the human organism during space missions A prediction method based on the concepts of homeostasis and general adaptation syndrome is outlined Some aspects of the application of expertise estimates and statistical approximation methods to the prediction of changes in various indices of crew members are discussed V P A77-11454 # Protein fractions and their enzyme activity in the rat myocardium after a 22-day space flight (Belkovye fraktsu i ikh fermentativnaia aktivnost' v miokarde krys posle 22-sutochnogo kosmicheskogo poleta) M S Gaevskaia, N A Veresotskaia, N S Kolganova, E V Kolchma, L M Kurkma, and E A Nosova Kosmicheskaia Bio/ogna i Aviakosmicheskaia Meditsina, vol 10, Sept-Oct 1976, p 37-40 9 refs In Russian No significant changes in the content of sarcoplasmic and myofibril proteins were found in the myocardium of rats after a 22-day flight aboard a biosatellite On the 2nd and 26th postflight days, the activity of aspartate and alanine ammotransferases of sarcoplasmatic proteins increased while the total activity of lactate dehydrogenase and its isoenzyme spectrum remained unchanged On the 2nd postflight day, the ATPase activity of myosin of the myocardium was substantially lower, but returned to the normal state on the 26th postflight day This decline in the ATPase activity of myosin may be regarded as an adaptive reaction to weightlessness (Author) A77-11455 # Effect of the 22-day space flight factors on the state of sex glands and reproductive function of rats (Vlnanie faktorov 22-sutochnogo kosmicheskogo poleta na sostoianie po- lovykh zhelez i reproduktivnuiu sposobnost' krys) G I Plakhuta Plakutma, L V Serova, A A Dreval', and S B Tarabrm Kosmicheskaia Biologua i Aviakosmicheskaia Meditsina, vol 10, Sept-Oct 1976, p 40-47 17 refs In Russian The paper presents the results of a morphological examination of the testes of Wistar rats after 22 days aboard the biosatellite Cosmos-605 Histological, histochemical, electron microscopic and biometric investigations of sex glands carried out 24 to 48 hours and 26-27 days after the flight showed that exposure of the rats to weightlessness and other space flight factors induced no morpho- logical changes in the spermatogenic tissues or disorders in the spermatogenic process of the rats The offspring of male rats that were exposed to 22-day weightlessness did not differ from the control animals with respect to the number of the newborn, their weight at birth, weight gam during the first postnatal month, resistance to hypoxia, etc (Author) A77-11456 " Aspects of optimizing rotation tests in elec- tronystagmography (Voprosy optimizatsu vrashchatel'nykh testov v elektronistagmografn) lu P Ozerov Kosmicheskaia Biologua i Aviakosmicheskaia Meditsina, vol 10, Sept-Oct 1976, p 48-52 9 refs In Russian Optimization of rotation tests is discussed with a view toward the classification of electronystagmograms A criterion for the effectiveness of thermal rotary, and other action on the vestibular analyzer, which takes into account the statistical properties of electronystagmograms of various classes, is proposed It is shown that variations! methods can be used effectively to determine the type of external effects This approach is used to identify optimal action in the discrimination between two electronystagmograms belonging to different classes The type of action is obtained in the form of a sequence of angular acceleration delta pulses V P A77-11457 ff Changes in central and peripheral hemo- dynamics, using prolonged antiorthostatic hypokmesia to simulate weightlessness (Izmenenna tsentral'noi i penfencheskoi gemo- dinamiki pri dlitel'noi antiortostaticheskoi gipokmezn kak modeli nevesomosti) D G Maksimov and M V Domracheva Kosmi- cheskaia Biologua i Aviakosmicheskaia Meditsina, vol 10, Sept -Oct 1976, p 52-57 30 refs In Russian A77-11458 # Periods of retamment of increased general resistance of the organism under different conditions of adaptation to oxygen deficiency (0 srokakh sokhranenna povyshennoi rezistent- nosti orgamzma pri razlichnykh rezhimakh adaptatsu k kislorodnoi nedostatochnosti) A A Aidarahev and A S Shanazarov Kosmi- cheskaia Biologua i Aviakosmicheskaia Meditsina, vol 10, Sept-Oct 1976, p 57-62 19 refs In Russian The altitude stability of white rats was studied for stepwise and nonstepwise acclimatization to heights of 3200 m Tests made on the third, seventh, fifteenth, thirtieth, forty fifth, and sixtieth days of the acclimatization process showed that stepwise acclimatization results in a higher resistance to extreme external factors as compared to nonstepwise acclimatization V P A77-11459 // Method of calculating the excess pressure in human lungs resulting from cabin decompression (Metod rascheta izbytochnogo davlenua v legkikh cheloveka pri dekompressii kabiny letatel'nogo apparata) V S lakovlenko Kosmicheskaia Biologua i Aviakosmicheskaia Meditsina, vol 10, Sept-Oct 1976, p 6268 5 refs In Russian The differential equations of the mathematical model proposed are well suited for obtaining computer-aided estimates of the positive pressure in human lungs upon explosive cabin decompression In addition, a simplified pressure computation method is developed which utilizes a special decompression diagram for a rigid tank connected by a hole of constant area with the cabin A distinctive feature of the method is that it takes into account both the efflux of the air from the lungs and their expansion during decompression The importance of simultaneously allowing for these two processes is demonstrated by an example V P A77-11460 ft Pathomorphological changes in rat organs in the case of chronic inhalation of a polyethylsiloxane fluid (Pato- morfologicheskie izmenenna v organakh krys pri khromcheskom mgaliatsionnom vozdeistvn pohetilsiloksahovoi zhidkosti) G P Tikhomov and lu P Bizin Kosmicheskaia Biologua i Aviakosmi- cheskaia Meditsina, vol 10, Sept Oct 1976, p 69-74 10 refs In Russian A77-11461 n Medical screening of flight personnel m certain types of chronic diseases of the myocardium (Vrachebnaia ekspertiza letnogo sostava pri nekotorykh formakh khronicheskikh boleznei miokarda) E T Malyshkm Kosmicheskaia Biologua i Aviakosmi- cheskaia Meditsina, vol 10, Sept-Oct 1976, p 74-78 8 refs In Russian 20 A77-11475 Cardiovascular diseases are known to be the most frequent cause of flight personnel disqualification The paper is concerned with the expert diagnosis of cardiosclerosis in flight personnel subjected to various kinds of psychological stress The major criteria for a correct diagnosis of myocardial diseases are shown to be (1) the presence or absence of symptoms for coronary or general circulation in- sufficiency from results of compulsory special complex of climco- physiological tests, (2) the pronouncedness of changes in the myocardium and blood vessels, along with the functional capacity of the cardiovascular system, (3) the evolutionary course of the underlying disease, (4) subjective feelings of flight personnel, (5) data on medical and service characteristics, along with the physician's dynamic observations, and (6) the presence or absence of individual burden associated with family history S 0 A77-11462 # Quantitative histochemical determination of creatine kinase activity in nanogram amounts of rat myocardium (Kohchestvennoe gistokhimicheskoe opredelenie aktivnosti kreatm- kinazy v nanogrammovykh kohchestvakh miokarola krysy) I B Krasnov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Sept-Oct 1976, p 78,79 10 refs In Russian A quantitative histochemical method is proposed for measuring the activity of creatine kinase in myocardium tissue fragments having a weight of dry tissue in the range 80-100 ng The enzyme activity is measured with respect to the phosphocreatme to-creatme reaction by means of fluorometnc measurement of creatine Results are pre sented for an experimental study in which the proposed method is used to determine the creatine kmase activity in the apex of the heart and the wall of the right ventricle in rats having stayed 22 days in space flight aboard the Cosmos 65 satellite and were sacrificed on the 2nd and 27th day after landing The results are compared with rats under the same conditions in a ground-based experiment without weightlessness The absence of differences in the level of creatine kinase activity in in-flight and ground-based animals indicate that after 22 days of space flight the rats possess total myocardial capacity to synthesize ATP from phosphocreatme and ADP, which supplies the energy necessary to sustain the contractile function of the heart S D A77-11463 {i Effect of orotic acid on weight dynamics in rats subjected to restrained motor activity (Vlnanie orotovoi kisloty na dmamiku vesa krys pri ogranichenn dvigatel'noi aktivnosti) B B Egorov and R I Gritsiuk Kosmicheskaia Bio/ogna i Aviakosmi- cheskaia Meditsma, vol 10, Sept-Oct 1976, p 80-82 In Russian Experiments were conducted on unrestrained and restrained mongel male rats weighing about 100 g to study the effect of orotic acid administration on the weight dynamics of the animals The rats were divided in 4 groups with 25 animals in each The control group contained unrestrained animals The 2nd group comprised un- restrained animals who received a daily dose of 0 1 g/kg body weight of orotic acid in their food The rats in the 3rd and 4th groups were submitted to restrained motor activity in cages, but only the 4th group received a daily dose of orotic acid The composition of peripheral blood by the 30th day of the experiment is found to remain within the norms of biological species A major conclusion is that reduction in the weight of the rats subjected to hypokmesia can be attenuated by administration of orotic acid S D A77-11464 ft Effect of blood redistribution in the human organism on the perception of body position in space (O vliiann pe'reraspredelenua krovi v orgamzme na vospruatie polozhenna tela v prostranstve) A S Barer and E P Tikhomirov Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Sept-Oct 1976, p 82, 83 In Russian Results are presented for decompression experiments on sub- jects provided with prophylactic vacuum suits, with decompression applied to the lower half of the body A series of experiments were conducted using the rotating chair with passive change of the subject's body position in space, while another series of experiments were carried out under conditions of weightlessness in a flying laboratory on a Keplenan trajectory Ground-based decompression tests revealed different feelings of head tilts, whereas flight decom- pression tests disclosed that weightlessness did not result in sub- jective feeling of transformation of body position in space The findings support the hypothesis about the influence of blood perfusion of individual vascular regions, particularly the brain, on the functional condition of the space analyzer in man S D A77-11465 // Responses of external respiration to +8 Gx overload for different training level of testees (Reaktsn vneshnego dykhanna na neregruzku +8 Gx pri razhchnom urovne tremrovan- nosti ispytuemykh) lu N Kamenskn and E B Shul'zhenko Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Sept-Oct 1976,p 83-85 12refs In Russian Pneumotachographic and gas exchange experiments were con- ducted on acceleration-trained and acceleration-untrained male sub- jects aged 20-40 yr to study the response of external respiration on a 8 Gx acceleration under heat moving toward back conditions for 60 sec Both groups are found to exhibit identical subjective feelings of acceleration, breathing difficulty, general fatigue, and unidirectional and significant changes in ventilation and gas exchange compared to initial levels (p less than 005) It is shown that the function,.of external respiration is less effective in the untrained than in the trained subjects, due to lack of training of the untrained subjects on the centrifuge S D A77-11466 n Genesis of vestibule-vegetative disorders under weightlessness conditions (O geneze vestibulo-vegetativnykh rasstroistv v uslovnakh nevesomosti) M B Zabutyl Kosmicheskaia Biologna i Aviakosmicheskaia Meditsma, vol 10, Sept-Oct 1976, p 85-88 11 refs In Russian The paper presents a critical discussion of the investigation of Brianov et al (1975) who, based on several examples from clinical practice and experimental studies on cosmonauts, have reduced the whole genesis of vestibular disorders in weightlessness state to hemodynamic changes in the blood vessel pool of the brain Evidence to refute the interpretation of many examples presented by these investigators is provided It is suggested to rely on the concept that the syndrome of motion sickness arising during weightlessness and other motion related diseases is based on the functional disorders occurring in the vestibular system Factors affecting the disorder of the vestibular system are identified S D A77-11475 Lack of effect of naloxone on pain perception in humans A El Sobky (Friern Hospital, London, England), P D Wall (University College, London, England), and J 0 Dostrovsky Nature, vol 263, Oct 28, 1976, p 783, 784 18 refs Research supported by the Medical Research Council Results are reported for experiments which demonstrate that the perception of experimentally induced pain in normal human subjects is not altered by the administration of the opiate antagonist, naloxone Five healthy adult subjects were tested on three different days for effects of intravenous injection of 0 4 to 0 8 mg of naloxone or a saline placebo, pain was induced by delivering incrementally increasing electric shocks Evaluations are made of threshold for sensation, pain threshold, severe-pain threshold, and maximal- tolerance current levels The results show that naloxone has no significant effect on any of these four parameters The lack of effect on pain perception is taken to suggest that under the experimental conditions employed, there is no significant ongoing release of a morphine-like compound within the brain F G M 21 A77-11476 A77-11476 Photoreceptor membrane carbohydrate on the intradiscal surface of retinal rod disks P Rohhch (Semmelweis Orvostudomanyi Egyetem, Budapest, Hungary) Nature, vol 263, Oct 28, 1976, p 789-791 24 refs An electron microscopic histochemical study of the carbo- hydrate component of the photoreceptor membrane in frog retinas is presented Two types of investigations were performed First, aldehyde-fixed frog retinas were embedded in different materials, and electron-microscopic histochemical reactions for carbohydrate detection were carried out on thin sections Second, ferntm-labelled concanavalm A was used to detect lectm-binding carbohydrates on the photoreceptor membrane The results of both investigations show the presence of a carbohydrate layer at the mtradiskal surface of frog retinal rods Assuming that rhodopsm is reponsible for the carbohydrate reaction, it is concluded that the carbohydrate com- ponent of rhodopsm musf be localized at the mtradiskal surface of the disk membrane f G M A77-11480 • The puzzle of the Martian soil R S Lewis Spaceflight, vol 18, Nov 1976, p 391-395 The puzzle presented by the Viking 1 life detection experiments is discussed It is not yet decided whether the reactions from treated soil, samples in these experiments are biological or some unearthly, peculiarly Martian form of inorganic soil chemistry The communica- tions problem of Viking 2 associated with gyroscope failure on the Orbiter is examined Three biological experiments are described the gas chromatograph mass spectrometer and X-ray fluorescence spec- trometer experiment, the gas exchange experiment, and the pyrolytic release or carbon assimilation experiment A number of Viking 1 and 2 photographs are presented B J A77-11546 Shuttle crew training revision needed Aviation Week and Space Technology, vol 105, Nov 8, 1976, p 124, 125, 127 Orbiter personnel training and human engineering of Orbiter facilities are dealt with Simulators and training facilities, training schedules, ranges of anthropometric measurements for personnel, sleeping accommodations, personal toilet and galley and waste management systems, and restraint systems for zero-g performance are described briefly Affirmative action with provisions for training minorities and women for Space Shuttle service dictate extension of the anthropometric range of equipment and instrument designs to accommodate average measurements of women personnel Standard- ization of mission phases, streamlining of mission planning, working advanced training into schedules, and combined vs separate training of flight crew and payload specialists are weighed" R D V A77-11550 # Life beyond the earth C Ponnamperuma (Maryland, University, College Park, Md ) Astronautics and Aero- nautics, vol 14, Nov 1976, p 50-55 The various aspects of the 'search for life' that is currently being carried out by Viking I and II are discussed, and the design of the Viking biology package is examined Laboratory experiments being conducted around the world in an attempt to unravel the perplexing results of the Viking biology experiments (gas-exchange (GEX), labelled release (LR), and pyrolytic release (PR)) are reviewed Some aspects of searching for intelligent life elsewhere in the universe are examined V P A77-11589 # The possibilities of Spacelab for solving medi- cal problems W Hepp (Dormer System GmbH, Fnedrichshafen, West Germany) British Interplanetary Society, Journal, vol 29, Nov 1976, p 755-759 Manned space missions have shown that weightlessness is the most important factor influencing living organisms This factor alone justifies biomedical experiments aboard Spacelab Measurements during past space missions have demonstrated many reactions of organisms, including redistribution of blood and body fluids, hormonal imbalance, loss of musculo-skeletal volume, decrease of metabolic rate, deformation of organs, disturbance of vestibular system and orientation, disturbance of biological rhythm. Proposals for new medical investigations are concerned with the reaction of the cardiovascular system, the disturbance of mineral balance, renal and pulmonary functions, osteogenesis, the etiology of motion sickness, and the disturbance of biological rhythm. Examples of the instru- mentation of a biomedical laboratory are given (Author) A77-11708 Abnormal patterns and physiological varia- tions in magnetocardiograms D Cohen (MIT, Cambridge, Mass.), E Lepeschkin (Vermont, University, Burlington, Vt), H Hosaka (Nihon Kohden Kogyo Co, Ltd, Tokyo, Japan), B F Massell (Children's Hospital, Boston, Mass ), and G Myers (Harvard Univer- sity, Boston, Mass ) Journal of Electrocardiology, vol 9, Oct 1976, p 398-409 10 refs Research supported by the American Heart Association, NSF Grant No C-670-2, Grants No PHS-HL-01486, No NIH-HL-14209 Magnetocardiograms (MCGs) of six subjects with representative cardiac abnormalities and of one well-studied normal subject are compared with the 12-lead ECGs and VCGs of these subjects The MCGs are recordings of the component of the magnetic vector which is normal to the skin, measured across the chest on a 5 cm x 5 cm grid, an example is also presented of a sequence of instantaneous MCG maps The heart abnormalities include myocardial infarction, angina pectoris, mtraventricular conduction disturbances, and ven- tricular hypertrophy The various MCG maps of the normal subject show MCG changes as a result of changes in body morphology (loss of weight), changes in the subject's position during recording, and changes as a result of exercise They are presented as a basis for understanding some of the variability of MCG maps (Author) A77-11709 Magnetic field produced by a current dipole D Cohen (MIT, Cambridge, Mass ) and H Hosaka (Ninon Kohden Kogyo Co , Ltd , Tokyo, Japan) Journal of Electrocardiology, vol 9, Oct 1976, p 409-417 13 refs The paper examines the nature of magnetocardiograms (MCG) by studying the basic element used in models which simulate the current sources in the heart the current dipole It is shown that the magnetic field of the dipole is made up of two parts the contribution by the dipole element itself, and the contribution by the current generated in the volume conductor by the dipole A theoretical analysis of the current dipole of the special shapes of the volume conductor is applied to the magnetic forward and inverse problems of magnetocardiography The zero to Bz contribution of the magnetic field (the component which is normal to the boundary of the volume conductor) is used in developing a method for estimating the presence of those dipole combinations which produce a suppressed surface potential B J A77-11710 The effect of the torso boundaries on the magnetocardiogram H Hosaka (Ninon Kohden Kogyo Co , Ltd , Tokyo, Japan), D Cohen, B N Cuffm (MIT, Cambridge, Mass ), and B M Horacek (Dalhousie University, Halifax, Canada) Journal of Electrocardiology, vol 9, Oct 1976, p 418-425 11 refs The magnetic field produced by a current dipole is made up of two parts the field from the dipole element, and from the current generated by the dipole in the volume conductor The volume conductor in the form of the human torso is investigated by computer simulation Three different heart-torso models are used The contributions to the normal field component (Bn) by the volume current (via the boundaries) and by the heart dipoles are computed For Bn the three models yield a ratio of boundary to dipole contribution in the same range, with 0 28 as the average The arrow map, developed previously to display Bn over special surfaces, is shown to be valid for the human torso, for visually estimating the heart dipoles (Author) 22 A77-12245 A77-11711 Visual determination of generators of the magnetocardiogram H Hosaka (Nihon Kohden Kogyo Co, Ltd , Tokyo, Japan) and D Cohen (MIT, Cambridge, Mass ) Journal of Electrocardiology. vol 9, Oct 1976, p 426-432 5 refs It was previously shown that Bn, the component of the heart's magnetic field which is normal to the chest, is largely produced directly by the generators in the heart, and that the distribution of Bn across the chest could be displayed as an arrow map which visually reveals the underlying dipole sources This paper presents arrow maps of one abnormal and two normal heart subjects for the purpose of demonstrating that the generators of the magneto- cardiogram can be coarsely estimated by visual inspection of these maps B J A77-11749 Beyond averaging - The use of discriminant functions to recognize event related potentials elicited by single auditory stimuli K C Squires and E Donchm (Illinois, University, Champaign, III ) Electroencephalography and Clinical Neuro- physiology, vol 41, Nov 1976, p 449-459 16 refs Grant No DAHC15-73-C-0318 A test of the stepwise discriminant analysis procedure for assessing single-trial event-related cortical potentials elicited in the course of EEG examination is described Discriminant functions were constructed from a data base composed of event-related potentials from 16 subjects who were presented trains of loud and soft tones (Loud tones occurred randomly on 10% of the trials ) Subjects either counted the loud stimuli or solved a hidden word puzzle Various discriminant functions at three electrode sites were obtained to examine the feasibility of performing pairwise discriminations between events which are defined by this procedure B J A77-11750 Activity of neuronal populations of human subcortical structures during sleep N I Moiseeva and Z A. Aleksanian (Akademna Meditsmskikh Nauk SSSR, Leningrad, USSR) Electroencephalography and Clinical Neurophysiology, vol. 41, Nov 1976, p 467-475 32 refs Multi-unit activity of neuronal populations of 14 subcortical structures was studied during drowsiness and sleep in patients with depth electrodes implanted in the brain for therapeutic purposes The mean firing rate of the multi-unit activity was found to decrease during slow-wave sleep in each cycle, and multi-unit activity was found to increase during paradoxical sleep In successive sleep cycles, the mean firing rate increased somewhat from cycle to cycle during slow sleep, and increased considerably during wakefulness after a sufficiently long sleep as compared with the initial background values Changes of the firing rate in separate structures may develop a few seconds prior to the clinical display of the REM phase B J A77-11892 Intracellular buffering of heart and skeletal muscles during the onset of hypercapnia J A Bettice (Case-Western- Reserve University, Cleveland, Ohio), B C Wang, and E B Brown, Jr (Kansas, University, Kansas City, Kan ) Respiration Physiology, vol 28, Oct 1976, p 89-97 17 refs Grants No NIH-HL-12231, No NIH-1-F22-HL-04000-01 A77-11899 Shuttle manipulator design reviewed Aviation Week and Space Technology, vol 105, Nov 1,1976, p 38,39 The paper deals with the Canadian-built remote manipulator system that will deploy and retrieve space shuttle payloads in orbit The first manipulator flight is planned on the third shuttle orbital flight when the long-duration exposure facility is expected to be deployed The manipulator system will be 50 ft long and have six degrees of freedom The shoulder joint (the point which attaches to the orbiter payload bay about 7 ft aft of the mam cabin bulkhead) will have pitch and yaw capability The unit's elbow joint that connects the two boom sections will have a pitch capability, while the RMS wrist joint that joins the end effector will have pitch, roll, and yaw Design capability is for maneuvering payloads on the order of 32,000 Ib Shuttle free-flying payload deployment simulations, currently under way, are discussed, along with some aspects of manipulator control V P A77-11997 Primitive grain clumps and organic compounds in carbonaceous chondntes. F Hoyle and N C Wickramasmghe (University College, Cardiff, Wales) Nature, vol 264, Nov 4, 1976, p 45,46 17 refs The paper proposes that physical conditions in prestellar molecular clouds favor the condensation of complex organic poly- mers, including ammo acids, within a matrix of smaller refractory particles It is shown that such composite gram dumps with dimensions exceeding 1 micron could be expelled along with gaseous material in protostellar cocoons, causing the widespread dispersal of biological activity in the Galaxy It is argued that gram clumps of the type considered may be identified with micron-sized inclusions found in carbonaceous chondntes It is suggested that large gram clumps of this type in a protoplanetary disk could also serve as accretion sites for smaller grains that condense within the disk, leading to the formation of planetesimals and, eventually, planets F G M A77-11999 Rivalrous texture stereograms. J E W Mayhew and J P Fnsby (Sheffield, University, Sheffield, England) Nature, vol 264, Nov 4, 1976, p 53-56 5 refs The way in which disparity information contained in nvalrous- texture stereograms is extracted from the two retinal images to produce stereoptic vision is investigated A test is conducted of the hypothesis that the disparity information carried by two monocular objects embedded in random textures might be extracted by pomt-for-pomt matching in a 'stereopsis channel' tuned to low spatial frequencies while other stereopsis channels tuned to higher spatial frequencies are in states of rivalry The results show that stereopsis can be obtained from rivalrous-texture stereograms only if there is spectral overlap in the two halves of the stereogram, irrespective of the monocular visibility of the texture contours themselves It is concluded that stereopsis in rivalrous-texture stereograms can be explained by spatial-frequency tuned stereopsis channels without any need to involve more complex stereopsis mechanisms incorporating monocular-object recognition FGM A77-12244 A mathematical model of the human tempera- ture regulatory system - Transient cold exposure response R G Gordon (California Polytechnic State University, San Luis Obispo, Calif), R B Roemer, and S M Horvath (California, University, Santa Barbara, Calif ) IEEE Transactions on Biomedical Engineering, vol BME-23, Nov 1976, p 434-444 50 refs Research supported by the University of California, Grant No AF-AFOSR-73-2455 A77-12245 Determination of oxygen tension by measure- ment of net charge transport G L Zick (Washington, University, Seattle, Wash ) IEEE Transactions on Biomedical Engineering, vol BME-23, Nov 1976, p 472-477 13 refs The paper describes the design, principles of operation, and capabilities of a pulsed amperometnc-electrode measurement system for determination of oxygen tension in blood The system consists of a gold cathode, Ag-AgCI anode, pulsed differential electrometer with dynamic gam, and a digital data acquisition unit The technique is shown to effectively evaluate the difference in charge transport that occurs during the polarization potential, so that it is possible to measure net charge transport which is proportional to the oxygen tension of whole blood as early as 1 msec after application of the polarization pulse The measurement technique also stabilizes the inherent electrode drift Other advantages are elimination of flow sensitivity and inadequate response time S D 23 A77-12288 A77-12288 Relations of the hydroxyproline concentration in the lungs to the lung weight, the silica and aluminum concentra- tions, and the dust dose, after repeated intratracheal coal dust application in a long-term test with rats (Beziehungen der Oxiprolm- konzentration in Lungen zum Lungengewicht, zu Kieselsaure- und Aluminiumkonzentrationen sowie zur Staubdosrs nach wiederholter mtratrachealer Kohlenstaubapplikation im Langzeitversuch an Ratten) W Ehm (Rhemisch-Westfalische Technische Hochschule, Aachen, West Germany) Staub-Remhaltung der Luft, vol 36, Oct 1976, p 410-417 71 refs In German Research supported by the Bergbau-Berufsgenossenschaft Bochum A77-12379 # A system of remote utilization of a computer during the processing of biological data (Ob odnoi sisteme distan- tsionnogo ispol'zovanna EVM pri obrabotke biologicheskoi mforma- tsii) Z 0 Zurabishvili, L G Kiknadze, and A Sh Chaduneli In Mathematical and technical cybernetics Tiflis, Izdatel'stvo Metsmereba, 1975, p 110-118 In Russian The paper considers the design of a computer system for the processing of biomedical data, with particular application to a laboratory of radiobiology The computer is used to process EEC and ECG data, to calculate auto- and cross-correlation functions, to perform coherent and factor analyses, and to obtain regression curves Block diagrams of the system are presented with particular attention given to remote interfacing of the computer with the biomstrumentation B J A77-12381 # Analysis of the problem of synchronizing the operation of different devices during the conversion and storage of digital electrocardiogram data (Analiz voprosa sinkhronizatsn raboty otdel'nykh ustroistv pri preobrazovann i nakoplemi chislovoi m- formatsn elektrokardiogramm) A Sh Chaduneli In Mathematical and technical cybernetics Tiflis, Izdatel'stvo Metsniereba, 1975, p 157-164 5refs In Russian A77-12400 Evidence of morphological and physiological transformation of mammalian cells by strong magnetic fields G I Malmin, V K Sharma, J C Houck (Children's Hospital, Washington, D C), W D Gregory, and L Morelli (Georgetown University, Washington, D C ) Science, vol 194, Nov 19, 1976, p 844-846 9 refs Cultures of L-929 and WI-38 cells, frozen to 4 2 K and exposed for 4 to 8 hours to 5000-oersted magnetic fields, were markedly inhibited in their growth as compared with controls In cultures grown on cover slips, approximately 7 days after exposure, mor- phologically distinct cells emerged and were propagated from generation to generation, 3 weeks later, in flask cultures, contact inhibition was abolished It is concluded that under certain experi- mental conditions, strong magnetic fields induce morphological and physiological transformations in target cells (Author) failure in patients with acute myocardial infarction are stressed Free communications are also included S D A77-12427 * Distribution of control decisions in remote manipulation A K Bejczy (California Institute of Technology, Jet Propulsion Laboratory, Pasadena, Calif ) In Conference on Decision and Control, 6th, and Symposium on Adaptive Processes, 14th, Houston, Tex, December 10-12, 1975, Proceedings New York, Institute of Electrical and Electronics Engineers, Inc , 1975, p 81-91 44 refs Contract No NAS7-100 The particular characteristics of the problem of distributing control decisions between man and computer in remotely controlled manipulation are discussed State of the art is reviewed from two viewpoints (1) specifications of both control commands and control context of sensor signals the operator inputs to the manipulator control computer, (2) operations the manipulator control computer performs on operator commands and realtime sensor signals to control the manipulator for a specified task JPL breadboard systems, system components, and control experiments are described related to the development and evaluation of manipulator control systems with capabilities of distributing control decisions between man and computer (Author) A77-12449 A maximum likelihood approach for identi- fying human operator remnant in a tracking task D W Repperger and A M Junker (USAF, Aerospace Medical Research Laboratory, Wright-Patterson AFB, Ohio) In Conference on Decision and Control, 6th, and Symposium on Adaptive Processes, 14th, Houston, Tex , December 10-12, 1975, Proceedings New York, Institute of Electrical and Electronics Engineers, Inc, 1975, p 534-540 16 refs By applying a maximum likelihood approach to identification with empirical data from a tracking task, the output signal uncorrelated with the input signal (a definition of human operator remnant) can be determined To obtain this remnant signal, a linear, stationary model describing the human is utilized The innovations signal is computed from the difference in the empirical data and the model's output The remnant can then be identified using the innovations sequence by computing the component of the output signal which is uncorrelated (or orthogonal) to the input signal Data from a Roll Axis Tracking Simulator is analyzed and remnant is identified to two phases of tracking (with and without motion information) (Author) A77-12425 Pulmonary hypertension Edited by J Widimsky Basel, S Karger AG (Progress in Respiration Research Volume 9), 1975 328 p $7425 The present collection of papers deals essentially with pulmo- nary hypertension in chronic obstructive bronchopulmonary disease with special attention to long-term studies, pulmonary hypertension at high altitudes, and pulmonary hypertension in left heart failure Normal hemodynamic values of pulmonary circulation both at rest and during exercise are discussed The promising aspects of long term oxygen treatment of chronic pulmonary hypertension in chronic bronchitis as well as the role of left heart in chronic obstructive bronchopulmonary disease are examined The reversibility of pulmo- nary vascular changes induced by permanent or intermittent high altitude is demonstrated along with the reversibility of right ventricular hypertrophy New aspects of therapy of acute left heart 24 N77-10779 STAR ENTRIES anaerobes and by several species of phototrophs Most data confirm that photoproduction of hydrogen by green algae is the result of decomposition of endogenic organic substances The possibility of hydrogen formation is determined by the presence of a specific enzyme called hydrogenase Author N77-10241*# Connecticut Univ Storrs THEORY OF ORTHODONTIC MOTIONS Susan Pepe, W Dennis °epe (Conn General Insurance Co) and Alvm M Strauss (Cincinnati Univ) In NASA Langley Res Center Advan in Eng Sci Vol 1 1976 p 103-110 refs Avail NTIS HC A16/MF A01 Proceedings from a conference on engineering advances are presented including materials science, fracture mechanics, and impact and vibration testing The tensile strength and moisture transport of laminates are also discussed N77-10260*# Cincinnati Univ Ohio BIOPYNAMICS OF DEFORMABLE HUMAN BODY MO- TION Alvm M Strauss and Ronald L Huston In NASA Langley Res Center Advan in Eng Sci Vol 1 1976 p 309-318 refs (Grants NSF ENG-75-21037 NSF ENG-75-06619) Avail NTIS HC A16/MF A01 Proceedings from a conference on engineering advances are presented including materials science fracture mechanics and impact and vibration testing The tensile strength and moisture transport of laminates are also discussed N77 10380*# Cincinnati Univ Ohio EXPERIMENT DESIGN FOR PILOT IDENTIFICATION IN COMPENSATORY TRACKING TASKS William R Wells In NASA Langley Res Center Advan in Eng Sci Vol 4 1976 D 1721-1731 refs Avail NTIS HC A22/MF A01 The following areas of flight science are discussed in detail (1) inviscid flow (2) viscous flow, (3) aircraft aerodynamics (4) fluid mechanics (5) propulsion and combustion, and (6) flight dynamics and control N77-10776*# Transemantics Inc. Washington DC MICROORGANISMS AS PRODUCERS OF HYDROGEN Ye N Kondratyeva and I N Gogotov Washington NASA Aug 1976 38 p refs Transl into ENGLISH of Izv Akad. n Nauk SSSR Ser Biol (USSR), no 1 Jan - Feb '976 p 69-86 (Contract NASw-2792) (NASA-TT-F-17131) Avail NTIS HCA03/MF A01 CSCL 06 M A review is presented of published data on micro-organisms capable of releasing molecular hydrogen the condition and ways of its formation the significance of this process and the possibility of practical applications Emphasis is placed on the release of hydrogen by chemotrophs such as obligate and faculative N77-10777*# National Aeronautics and Space Administration Lyndon B Johnson Space Center Houston Tex BIOPROCESSING IN SPACE (1976) 15 p Prepared in cooperation with Boeing Co Seattle (Contract NAS9-13655) INASA-TM-X-74157) Avail NTIS HC A02/MF A01 CSCL 06B Space processing accomplishments onboard Skylab and Apollo Soyuz are reviewed Possible applications of bioprocessing experiments to be carried on space shuttles and Spacelab are explored A H N77-10778# Medical Biological Lab RVO-TNO Rijswijk (Netherlands) FIRST RESULTS OF AN INVESTIGATION OF THE EFFECTS OF MICROWAVE RADIATION WITH LOW POWER DENSITY ON THE BEHAVIOR OF RATS [EERSTE RESULTATEN VAN EEN ONDERZOEK NAAR DE EFFECTEN VAN MICROG- OLFSTRALING MET LAGE VERMOGENSDICHTHEDEN OP HET GEDRAG VAN RATTEN] B Roberti G H Heebels (Lab for Electron Develop of the Armed Forces Oegstgeest Neth) J C M Hendncx (Lab for Electron Develop of the Armed Forces Oegstgeest Neth ) and 0 L Wolthuis [1975] 14 p refs In DUTCH. ENGLISH summary (MBL-1974-15 TDCK-64396) Avail NTIS HC A02/MF A01 The effect of microwave radiation on the spontaneous motor activity of the male Wistar rat was investigated Rats were exposed to microwaves of 107 GHz continuous wave (CW) 3 GHz CW or 3 GHz pulsed wave (PW) with power densities of about 1 mW/sq cm for 185 h Moreover, a small number of rats was irradiated with 3 GHz PW at 25 mW/sq cm for 17 days Spontaneous activity was automatically measured and analyzed in 5 classes of movements of increasing amplitudes After termination of the irradiation no differences were found between the irradiated rats and the non-irradiated controls In the experiment with 3 GHz PW at 25 mW/sq cm for 17 days rats were used that had been pretramed to a constant top performance on a 2 m long runway Their running-times were not influenced by the irradiation No deleterious effects of the microwave irradiation have been found as yet Author (ESA) N77-10779# Medical Biological Lab RVO-TNO Rijswijk (Netherlands) THE CONTRACTION PROLONGING ACTION OF 9-AN- THROIC ACID (ANCA) ON THE ISOLATED RAT DI- APHRAGM AND THE EFFECTS OF SOMAN ON THIS PHENOMENON V J Nickolson and F L vanVelsen Sep 1975 45 p refs In DUTCH. ENGLISH summary (MBL-1975-25, TDCK-66841) Avail NTIS HC A03/MF A01 The effects of the sodium salt of 9-anthracene carboxylic acid (9-anthroic acid ANCA) and the cholmesterase inhibitor soman (3 3-dimethyl-2-butyl 2-methyl phosphonofluondate) on the isolated rat phrenic nerve diaphragm preparation were investigated Materials and methods used are presented incubation and stimulation influence of the stimulation frequency on the contraction prolonging effect o' ANCA direct stimulation experiments in calcium-free medium experiments with ouabame experiments with different chloride concentrations, and determina- tion of the Na K, Ca and Mg content The results of the determination of the contraction prolonging effect of ANCA are presented and discussed ESA 25 N77-10780 N77-10780* National Aeronautics and Space Administration Ames Research Center, Moffett Field Calif THERMISTOR HOLDER FOR SKIN TEMPERATURE MEAS- UREMENTS Patent John E Greenleaf and Bill A Williams inventors (to NASA) Issued 5 Oct 1976 4 p Filed 29 Sep 1975 Supersedes N75-33642 (13 - 24 p 3077) (NASA-Case-ARC-10855-1. US-Patent-3,983 753. US-Patent-Appl-SN-617612 US-Patent-Class-73-343R US-Patent-Class-128-2H) Avail US Patent Office CSCL 06B An improved thermistor holder structure is disclosed which facilitates skin-temperature measurement The device includes a cylindrical plastic housing with tab extensions that permits the apparatus to be held to a skin surface by suitable elastic members or the like Ventilation openings are provided in the plastic housing to permit air circulation An adjustable resilient metal arm with a thermistor holding cup formed at one end is secured to the interior surface of the plastic housing such that the holding cup is located at the center of the housing A thermistor temperature sensor is inserted into and held in the cup by interference fit Official Gazette of the U S Patent Office N77-10782*# Transemantics Inc . Washington. D C EXPERIMENTS ABOARD BIOSATELLITES KOSMOS-690 AND KOSMOS-782 Yu Gngoryev and A Sedov Washington NASA Sep 1976 8 p Transl into ENGLISH from Med Gazeta (USSR) 9 Apr 1976 p 3 (NASA-TT-F-17215) Avail NTIS HC A02/MF A01 CSCL 06R An artificial source of irradiation was installed aboard the biosatellite Cosmos 690 for simulating the effect of solar flares on white rats The bioblok microlaboratory was carried aboard the Cosmos 782 satellite Bioblok consisted of a pair of identical units gathered in a single coordinate system of alternating layers of dielectric track detectors and biological objects enclosed in restraining plates The experiment was conducted to study the biological effect of heavy ions of galactic cosmic irradiation The objects used in the experiment were Brachiopoda subclass eggs yeast cell colonies tobacco seeds and Arabidopsis Author N77-10783*# Transemantics Inc . Washington. D C SECOND EXPEDITION OF THE SALYUT-4 ORBITAL STATION CERTAIN RESULTS AND TASKS OF MEDICAL RESEARCH O G Gazenko and A D Yegorov Washington NASA Oct 1976 30 p Transl into ENGLISH from Vestn Akad Nauk SSSR (USSR) no 4 Apr 1976 p 25-36 (NASA-TT-F-17223) Avail NTIS HC A03/MF A01 CSCL 06 P Effects of the Salyut 4 mission on the human organism and other medical problems which remain to be solved are discussed Research in space medicine is being directed to (1) perfection of prediction methods of a cosmonauts possible functional state disorders in long-term flights. (2) further study of adaptation. (3) quantitative evaluation of the role of certain flight factors and the organism s response reactions and (4) perfection of a method of applying preventive measur.es and developing new measures Author N77-10784# Medical Biological Lab RVO-TNO Rijswijk (Netherlands) MUTAGENICITY TESTING OF SOME NITROFURAN DERIVATIVES AND SOME CHLORINATED HYDROCAR- BONS I E Mattern Sep 1975 18 p refs In DUTCH ENGLISH summary (MBL-1975-22 TDCK-66737) Avail NTIS HC A02/MF A01 The mutagenicity of the nitrofuran derivatives nitrofurantom mtrofurdzone nifuroxine 5-nitrofuraldehyde diacetate and trans-2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide (AF2) and of the chlorinated hydrocarbons pentachlorophenol dieldnn 2 2 - dichlorodiethylether trichloroethyl phosphate and of the two PCB mixtures aroclor 1242 and 1254 was determined using the Ames test using salmonella typhimunum or Eschenchia coll bacteria In decreasing order of potency 5, 1 3 and 4 were mutagenic for Eschenchia coli All substances induced base pair substitution mutations From the chlorohydrocarbons tested only 22- dichlorodiethylether was mutagenic Also the nitrofuran containing waste water of a pharmaceutical factory was tested and was found to induce mutations even in a 10.000-fold dilution ESA N77-10785# Medical Biological Lab RVO-TNO Rijswijk (Netherlands) THE FUNCTION OF THE GASTROINTESTINAL CHANNEL OF THE RAT DURING SHOCK [DE FUNCTIE VAN HET MAAG-DARMKANAAL VAN DE RAT IN SHOCK] 0 deJong M Wijnans and P vanEck 1975 29 p refs In DUTCH, ENGLISH summary (MBL-1975-16, TDCK-66658) Avail NTIS HC A03/MF A01 The reduction or postponement of shock by drinking salt-containing water was investigated Rats were bled and by means of 1-131 polyvmylpyrrolidon (PVP), which is little resorbed in the gastrointestinal channel, the influence of shock on transport from the stomach was established The experiment was repeated with a labeled 0 9% NaCI solution Results were compared with those of non-shocked animals In severely shocked rats the salt fluid administered was retained to a considerable degree in the stomach apparently due to atonia of the stomach wall There also appeared to be .atonia of the intestinal wall ESA N77-10786# Cleveland Clinic Foundation Ohio Dept of Artificial Organs BIOLIZED LATEX POLYURETHANES Annual Report. 1 Dec 1974 - 30 Nov 1975 Y Nose, G Picha H Kambic D F Gibbons, and R Martin Mar 1976 43 p refs (Contract N01-HB-3-2914) (PB-253085/5 NIH-N01-HB-3-2914-3) Avail NTIS HC A03/MF A01 CSCL 06L The potential use of latex polyurethanes (LPU) in the development of biolized materials was evaluated Nine LPU's including both polyester and polyether types were studied in addition to Biomer as a control The pure polymers unbiohzed were optimized with respect to curing time and temperature The initial areas of development of the LPU s were processing mechanical performance, tensile properties as determined hydrolysis histocompatibihty and hemocompatibihty The latex urethanes have been preliminarily screened, evaluated for feasibility and are still in the process of being optimized Six materials have been eliminated from the study while the three LPU s still under investigation were found capable of withstand- ing severe hydrolytic environment up to 15 days Biolization was not found to significantly alter the histopathological response which seems to be controlled by the LPU However the LPU s as tested in the in vitro closed kinetic test cell showed better performance than the Silastic control and all biolized LPU s showed significant improvement over the nonbiolized LPU s GRA N77-10787# Calspan Corp . Buffalo N Y INTERFACIAL BIOPHYSICS OF MATERIALS IN CONTACT WITH BLOOD Annual Report. 16 Jan 1975 - 15 Jan 1976 R E Baier. C Akers S Perlmutter, V L Gott (Johns Hopkins Umv Baltimore) and J ORiordan (Johns Hopkins Univ Baltimore) 1 Mar 1976 110 p (Contract HB-3-2953) (PB-2531 17/6 CALSPAN-W06-EB-5307-M-18 NIH/NHLI-N01-HB-3-2953-2) Avail NTIS HC A06/MF A01 CSCL 06L The nature sequence and seventy of early adsorptive and cellular adhesive events were established at the boundary between blood and nonphysiologic materials proposed for blood contact applications in a variety of medically useful devices Task 1 involves the production and analysis of interfacial layers of proteins and polypeptides Task 2 is devoted to the in vivo evaluation of competing concepts of thromboresistance mainly investigating low surface-free-energy and high surface-free-energy materials 26 N77-10794 in the canine vena cava ring test Task 3 provides for characteriza- tion of the surface properties of biocompatible materials from 12 separate sources GRA N77-10788# General Electric Co Schenectady. N Y Research and Development Center DEVELOPMENT AND EVALUATION OF AN ULTRASONIC IMAGING SYSTEM Annual Report, 15 Jun 1975 - 15 Mar 1976 Paul M Gnffen. Henry A F Rocha Charles E Thomas, and John R M Viertl 31 Mar 1976 84 p refs (PB-252561/6 SRD-76-035 NIH/NHLI-N01-H V-5-2966-1) Avail NTIS HC A05/MF A01 CSCL 06L Detection and characterization of atheroma requires much higher resolution than available in current ultrasonic imaging systems The purpose was to implement laser shock excitation techniques for wideband acoustic generation and optimized electrostatic receivers for wideband acoustic detection It was shown that very short acoustic pulses can be generated having useful energy in the 2 MHz to 20 MHz range Electrostatic receivers were fabricated and tested which are as sensitive as a PZT crystal at or near their tuned frequency Evaluation of a coupled laser shock excitation acoustic generator and an electrostatic receiver indicated that the useful acoustic range was 1 to 50 MHz Iterative improvements are continuing GRA N77-10789# Michigan State Univ East Lansing Div of Engineering Research INDUCED EM FIELD AND ABSORBED POWER DENSITY INSIDE HUMAN TORSOS BY 1 TO 500 MHz EM WAVES Kun-Mu Chen and B S Guru Apr 1976 184 p refs (Grant NSF ENG-74-12603) (PB-254247/0. TR-1) Avail NTIS HC A09/MF A01 CSCL 06R Numerical results on the internal EM field and absorbed power density inside a human torso induced by EM waves of frequencies ranging from 1 to 500 MHz and of both vertical and horizontal polarizations are presented GRA N77-10790*# National Aeronautics and Space Administration Langley Research Center Langley Station Va SUBJECTIVE RESPONSE TO COMBINED NOISE AND VIBRATION DURING FLIGHT OF A LARGE TWIN-JET AIRPLANE , Sherman A Clevenson Washington Oct 1976 43 p refs (NASA-TM-X-3406 L-10578) Avail NTIS HC A03/MF A01 I CSCL 05H ___ _ -"^ A NASA twin-jet airplane was used to obtain controlled noise and vibration environments during flight while obtaining subjective responses from 13 passenger-subjects (6 females and 7 males) Subjective ratings of overall comfort comfort when considering only vibration and comfort when considering only noise were obtained during times of different vibration and noise environments Passenger-subjects were able to distinguish and rate noise better than vibration In addition there was a statistically significant difference in ratings of ride comfort due to both sex type and flight experience Males rated flying discomfort much more severely than females when rating the overall ride and the ride when considering only the noise environment Experienced passengers also rated the overall ride to be more uncomfortable than inexperienced passengers Author N77-10791*# National Aeronautics and Space Administration Langley Research Center Langley Station Va NOISE AND VIBRATION RIDE COMFORT CRITERIA Thomas K Dempsey Jack D Leatherwood and Sherman A Clevenson Oct 1976 25 p refs Presented at the 92d Acoustical Soc of Am Meeting San Diego Calif 16-19 Nov 1976 (NASA-TM-X-73975) Avail NTIS HC A02/MF A01 CSCL 05H \ Two of the most important factors namely vibration and noi^e were studied to (1) determine whether composite or separate noise and vibration criteria are needed for the prediction of ride quality (2) determine a noise correction for the previously- defined vibration criteria of the ride quality model (3) assess whether these noise corrections depend on the nature of the vibration stimuli i e . deterministic as opposed to random and (41 specify noise-vibration criteria for this combined environment Th6 stimuli for the study consisted of octave bands of noise centered at 500 or 2 000 Hz and vertical vibrations composed of either 5 Hz sinusoidal vibration or random vibrations centered at 5 Hz and with a 5 Hz bandwidth The noise stimuli were presented at levels ranging from ambient to 95 dBIA) and the vibrations at levels ranging from 002 to 0 13g rms Author N77-10792*# Minnesota Univ St Paul Dept of Food Science and Nutrition STORAGE STABILITY AND IMPROVEMENT OF INTERME- DIATE MOISTURE FOODS. PHASE 3 Final Report. Aug 1974 - Aug 1975 T P Labuza 1975 386 p refs (Contract NAS9-12560) (NASA-CR-151004) Avail NTIS HC A17/MF A01 CSCL 06H Methods were determined for the improvement of shelf-life stability of intermediate moisture foods (IMF) Microbial challenge studies showed that protection against molds and Staphylococcus aureus could be achieved by a combination of antimicrobial agents humectants and food acids Potassium sorbate and propylene glycol gave the best results It was also confirmed that the maximum in heat resistance shown by vegetative pathogens at intermediate water activities also occurred in a solid food Glycols and sorbitol both achieve browning inhibition because of their action as a medium for reaction and effect on viscosity of the adsorbed phase Chemical availability results showed rapid lysme loss before visual discoloration occurred This is being confirmed with a biological test using Tetrahymena pynformis W Accelerated temperature tests show that effective- ness of food antioxidants against rancidity development can be predicted however the protection factor changes with tempera- ture BHA was found to be the best antioxidant for iron catalyzed oxidation Author N77-10793*# Decision Science. Inc San Diego Calif A COMPUTER PROGRAM FOR THE USE OF SENSITIVITY ANALYSIS IN DISPLAY EVALUATION Michael L Mout and George H Burgm 1976 72 p refs (Contract NAS1-13734) (NASA-CR-145060) Avail NTIS HC A04/MF A01 CSCL 05E A description is provided of the Display Evaluation computer program some results of this program and comparison of these results with a simple experiment A detailed description of the experiment and data analysis are also included Author N77-10794# Aerojet Nuclear Co Idaho Falls Idaho HUMAN FACTORS IN DESIGN M G Bullock and R J Nertney Feb 1976 138 p (Contract E( 10-11-1375) (ERDA-76-45) Avail NTIS HC A07/MF A01 Human factors is a subject which is becoming of greater importance to the equipment designer One reason is the increasing need for high reliability systems Total reliability is dependent upon both the basic hardware reliability built into the design and the way that the human operator manipulates and uses the equipment It is pointed out that a higher degree of responsibility for use and misuse implies that human factors are of more importance in the commercial design processes now than in the days when liability was more completely limited to product mechanical defects This in turn, means that the contemporary design engineer must have a greater knowledge of human factors than has been required jn the past if he is to keep pace with the times Author (ERA) 27 N77-10795 N77-10795# Kaman Sciences Corp Colorado Springs Colo A SOLID STATE DIGITAL DATA RECORDER FOR MONI- TORING ANTHROPOMORPHIC DUMMY IMPACT ENVI- RONMENTS Final Report Randolph J Wolf May 1976 73 p refs (Contract DOT-HS-4-00927) (PB-254036/7. K-76-28UIR) DOT-HS-801-907) Avail NTIS HC A04/MF A01 CSCL 13L A solid state digital data recorder was developed for use in monitoring anthropomorphic dummy impact environments The recorder was designed to be a very general miniature data acquisition system and was mounted in the pelvic assembly of a 50th percentile anthropomorphic dummy An eight channel system was evaluated in a sled test series simulating a 30 mph vehicle-barrier impact The dummy/recorder system was also evaluated in five vehicle collisions During these tests the system successfully captured and stored impact information on all thirteen collisions in which it participated GRA N77-10796# National Inst for Occupational Safety and Health Morgantown W Va Testing and Certification Lab DETERMINATION OF FACEPLATE CARBON-DIOXIDE CONCENTRATION LEVELS OF SELF-CONTAINED BREATH- ING APPARATUS Samuel L Terry Nov 1975 24 p refs (PB-252695/2 NIOSH/TC/R-003) Avail NTIS HC A02/MF A01 CSCL 06K While an individual is wearing a self-contained breathing apparatus he is exposed to various concentration levels of expired carbon dioxide These levels adversely affect the users behavior and the respirators performance Because of the variability among test subjects, this procedure has been standardized to a machine-test method using a breathing machine with a sedentary cam which operates at 14 5 respirations per minute with a minute volume of 105 liters A 5% air carbon dioxide mixture is fed into the facepiece during exhalation and the average exposure level during inhalation is calculated Experimental design limits this method to breathing apparatus with less than 1100 cc of effective dead-air space The standard deviation of C02 concentra- tions obtained by this method is less than 0 1% C02 at a 95% confidence level GRA N77-10797# National Inst for Occupational Safety and Health. Morgantown W Va Testing and Certification Lab PROCEDURE FOR CONTINUOUS-FLOW RESPIRATOR FLOWRATE DETERMINATION Steven W Uenhart Nov 1975 20 p refs (PB-252694/5 NIOSH/TC/R-004) Avail NTIS HC A02/MF A01 CSCL 06K The test procedure was prepared as a guide to a method of determining the volume of air delivered by a continuous flow supphed-air respirator The method has the advantage that the test results can be documented on recorder paper The respiratory inlet covering of a supphed-air system is placed in a container with an outlet, the outlet of the container is connected to a pneumotachometer and pressure transducer Flow rates delivered by the respiratory inlet covering at specified pressures and air supply hose lengths are recorded and determined from a graph prepared during pneumotachometer calibration GRA N77-10798# National Inst for Occupational Safety and Health. Morgantown. WVa Testing and Certification PROCEDURE FOR TESTING STRENGTH OF HOSE AND COUPLINGS Steven W Lenhart Feb 1976 18 p ref (PB-252696/0 NIOSH/TC/R-006) Avail NTIS HC A02/MF A01 CSCL 06K A procedure was developed for testing the strength of hose and couplings of supplied air respirators Hose and couplings used with Types A AE 8 and BE respirators are tested with a pull of 113 kilograms for five minutes Hose and couplings used with Types C and CE respirators are tested with a pull of 45 kilograms for five minutes and also subjected to an internal air pressure GRA N77-10799*# Joint Publications Research Service Arlington Va ON THE POSSIBLE UNIQUENESS OF INTELLIGENT LIFE IN THE UNIVERSE I S Shklovskiy Washington NASA Oct 1976 19 p Transl into ENGLISH of Report PR-262. Academy of Sciences USSR Inst of Space Res Moscow, 1976 p 1-30 (NASA Order W-13183) (NASA-TT-F-17247) Avail NTIS HC A02/MF A01 CSCL 03 C The modern conception of an expanding universe rejects theories of cosmic wonders transformation of matter or superintendent cosmic factors as sources of intelligent life on earth Life emerged on earth and became intelligent as the result of an extremely rare combination of improbable circumstances The expansion of intelligent life in the universe will be ac- complished by the establishment of artificial biospheres orbiting the moon or stationed in galaxcies Communications between these space colonies will rely on computer technology and radio astronomy A H N77-11639# Institut Franco-Allemand de Recherches St Louis (France) INFLUENCE OF THE PEAK PRESSURE AND DURATION OF IMPULSE NOISE (GUN FIRE) ON THE HEARING OF THE GUINEA PIG [INFLUENCE DE LA PRESSION DE CRETE ET DE LA DUREE D'UN BRUIT IMPULSIF (BRUIT D'ARME) SUR L'APPAREIL AUDITIF DU COBAYE] A Dancer R Franke G Baillet P Vassout and F Devnere 27 Mar 1975 35 p refs In FRENCH (Contract DRME-74/024) (ISL R-109/75) Avail NTIS HC A03/MF A01 The influence of peak pressure and the duration of impulse noise (gunfire type) was investigated in guinea pigs The experimental setup used is described Results from audiometnc techniques based on the Preyer reflex and on the recording of cochlea potentials have evidenced the following factors the evolution of the auditory sensitivity recuperation is of the 10 log t form the importance of auditory fatigue seems related to the noise peak pressuie according to 40 log delta p and the auditory loss increases according to 20 log delta p The increase of noise duration has no effect on auditory losses ESA N77-11640# Institut Franco-Allemand de Recherches, St Louis 'France) INFLUENCE OF A PRECURSOR NOISE ON THE GLOBAL ACTION POTENTIAL CONSECUTIVE TO AN IMPULSE NOISE IN THE GUINEA PIG [INFLUENCE D'UN BRUIT PRECURSEUR SUR LE POTENTIEL D'ACTION GLOBAL CONSECUTIF A UN BRUIT IMPULSIF CHEZ LE COBAYE] R Franke and A Dancer 22 Apr 1975 26 p refs In FRENCH (ISL-R-115/75) Avail NTIS HC A03/MF A01 The inhibitive effect of a precursor noise in Guinea pigs was investigated studying the global action cochlean potential in order to reduce the stress (startle) provoked by the impulse noise Experimental results show that for a given impulse noise (0 5 mbar overpressure 2 ms duration) a precursor noise consisting of a click identical to the impulse noise but of reduced amplitude, provokes a 33% weakening of the global action potential In addition a precursor noise consisting of a gust of white noise with maximum pressure (100 dB) at impulse noise incidence provokes a 70% weakening of the global action potential The latter effect can be strengthened by a masking effect ESA N77-11641# Institut Franco-Allemand de Recherches St Louis (France) STUDY OF METABOLIC RESPONSE VARIATION TO AN ACOUSTIC AGGRESSION [ETUDE DE LA VARIATION DE LA REPONSE METABOLIQUE A UNE AGRESSION D'ORI- GINE ACOUSTIQUE] 28 N77 11646 P Vassout and F Devriere 29 May 1975 34 p refs In FRENCH (ISL-R-120/75) Avail NTIS HC A03/MF A01 The metabolic response of rats to an acoustic variation was investigated using a noise generator simulating sonic boom waves of N profiles The operational conditions and experimental setup are presented Experimental results including the dosage of blood plasma potassium, and glucose as well as the dosage of catecholammes in rat unne after exposure to N acoustic waves, are discussed A relation was found between the recovery time to return to base metabolism level and the peak pressure In addition, isoeffect curves displaying peak pressure and exposure time versus the excretion of urine catecholamme were estab- lished ESA N77-11642# North Carolina Univ, Chapel Hill Dept of Bacteriology VIRION AGGREGATION AND DISINFECTION OF WATER VIRUSES BY BROMINE Final Report. Apr. 1974 - May 1975 D Gordon Sharp May 1976 45 p refs (Contract EPA-R-802946) (PB-253087/1. EPA-600/2-76-163) Avail NTIS HC A03/MF A01 CSCL 06M Direct evidence is provided for the kind and degree of aggregation that was present among the virions that were treated with bromine as well as the PFU liters of the starters and the survivors A dynamic system in which disinfectant exposure time intervals as low as 0 5 seconds was developed Polio and reovirus preparations, containing essentially all single particles, as indicated by electron microscopy, were tested in this system The results indicated that reovirus single particle suspensions were 30 times as sensitive to bromine as poliovirus single particle suspensions both showing essentially first order reaction kinetics with disinfection rates of 3 log base 10 per second and 6 log base 10 units per minute respectively GRA N77-11643# Naval Research Lab Washington DC Marine Biology and Biochemistry Branch AN EVALUATION OF A FUEL-SOLUBLE ORGANOBORON BIOCIDE FOR CONTROL OF SULFATE REDUCING BAC- TERIA IN SHIPBOARD FUEL TANKS Interim Report Dorothea E Klemme and Rex A Neihof Apr 1976 13 p refs (NRL Proj G04-01A SS0240201) (AD-A024017 NRL-MR-3259) Avail NTIS HC A02/MF A01 CSCL 21/4 A biocide composed of a mixture of two dioxabonnane derivatives has been evaluated in test-tube assays and in large-scale test systems simulating conditions in shipboard seawater-displacement fuel tanks A concentration of ap- proximately 20,000 ppm in the water phase was required to control sulfate-reducmg bacteria of marine origin in a mixed population of microorganisms It is not likely that this concentration can be attained in the relatively large volumes of water present in water-displacement fuel tanks by partitioning from a feasible concentration in the fuel phase A preferable alternative for controlling microorganisms in water-displacement fuel tanks is the addition directly to the water phase of one of several previously evaluated water-soluble, fuel-insoluble biocides known to be effective at concentrations of 50 to 100 ppm Author (GRA) N77-11644/T1 Advisory Group for Aerospace Research and Development. Pans (France) THE PATHOPHYSIOLOGY OF HIGH SUSTAINED +G SUB z ACCELERATION. LIMITATION TO AIR COMBAT MAN- OEUVERING AND THE USE OF CENTRIFUGES IN PER- FORMANCE TRAINING Neville P Clarke ed (Texas A and M Univ. College Station) and Sidney 0 Leverett Jr ed (School of Aerospace Med) Oct 1976 77 p refs Papers presented at the Aerospace Med Panel Specialists Meeting Copenhagen 5-9 Apr 1976 (AGARD-CP-189) Avail NTIS HC A05/MF A01 The risk of significant cardiovascular change to a tactical fighter pilot from exposure to aerial combat accelerations such as those postulated for new high performance aircraft is investigated Miniature swine were used as animal models to study the effects of high sustained acceleration The seatback angle was assessed in relation to the psycho-physiological and physio-chemical changes in the human body The utilization of the human centrifuge for training military pilots for air combat maneuvering +Gz stress is covered including the stress response and stress tolerance during the maneuvers Centrifuge training improves the pilot s ability to effectively perform in the high G environment For individual titles see N77-11645 through N77-11653 N77-11645| School of Aerospace Medicine Brooks AFB, Tex CHANGES IN CLINICAL CARDIOLOGIC MEASUREMENTS ASSOCIATED WITH HIGH +G SUB z STRESS Kent K Gillmgham and Phelps P Crump In AGARD The Pathophysiol of High Sustained +G sub z Acceleration. Limitation to Air Combat Manoeuvenng and the Use of Centrifuges in Performance Training Oct 1976 9p refs Avail NTIS HC A05/MF A01 Because of reports of subendocardial hemorrhage and myofibrillar degeneration in animals exposed to sustained high G loads, questions have been raised regarding the safety of exposing pilots and human subjects to the similar G-stress levels likely to be encountered in the new high performance fighter aircraft Noninvasive clinical cardiologic data, including ECGs vectorcardiograms, systolic time intervals, and maximal treadmill stress tests were obtained from two groups of subjects before and at several times after exposure to high-G stress The group exposed to the greater G stress developed moderate cutaneous petechiasis and had other minor physical findings after the G stress, but showed few significant changes in cardiologic data serum total CPK and LDH levels rose and preelection period shortened at 48 h poststiess The group exposed to the lesser G stress had no symptoms following the G stress, but the vectorcardiograms revealed trans'ent T-loop angle changes and preelection period measured at one week poststress was significantly decreased Because the serum enzyme changes were noncardiac in origin, and because the few other changes were not in a direction indicative of cardiac damage the G stresses imposed were not significantly injurious Author N77-11646# School of Aerospace Medicine, Brooks AFB, Tex VENTRICULAR PATHOLOGY IN SWINE AT HIGH SUS- TAINED + G SUB z William F MacKenzie and Russell R Burton In AGARD The Pathophysiol of High Sustained 4 G sub z Acceleration Limitation to Air Combat Manoeuvenng and the Use of Centrifuges in Performance Training Oct 1976 3 p refs Avail NTIS HC A05/MF A01 Study of miniature swine has shown two distinct types of cardiac pathology as the result of exposure to HSGz Grossly visible endocardial hemorrhage of varying degrees of seventy occur consistently In severe cases damage to Purkmje fibers is adequate to explain some of the ECG changes that have been found A stress myocardiopathy is also found characterized by randomly distributed single or grouped degenerate and dead muscle fibers surrounded by normal appearing fibers Electron microscopically the lesion is characterized by profound changes in the contractile myofibnls known as myofibrillar degeneration These changes have also been found in Purkmje fibers It appears that the subendocardiat hemorrhage is related to the combination of tachycardia strong contractions (positive motropism) and a hypovolemic ventricle The stress myocardiopathy has a distinctly different and complex etiology The ultrastructural lesions are not indicative of a primary hypoxic insult although hypoxia undoubtedly contributes Author 29 N77-11647 N77-11647# Naval Air Development Center. Warmmster. Pa Crew Systems Dept PSYCHO-PHYSIOLOGICAL AND PHYSIO-CHEMICAL ASSESSMENT OF ACCELERATION INDUCED CHANGES IN HUMANS POSITIONED IN VARIOUS SEATBACK ANGLE CONFIGURATIONS Victoria M Voge Harald J VonBeckh, and Jeffry S Bowman In AGARD The Pathophysiol of High Sustained +G sub z Acceleration. Limitation to Air Combat Manoeuvenng and the Use of Centrifuges in Performance Training Oct 1976 9 p refs Avail NTIS HC A05/MF A01 A series of high-G tests were conducted on pilot/subjects using the multi-posture adjustable centrifuge test seat An increase in human tolerance to sustained acceleration was demonstrated by employing several seat configurations A significant increase 11 G tolerance was demonstrated with each increase in seatback angle The position of the lower legs made no significant difference Ten subjects between the ages of 20 and 44 with various body builds and G experience took part All had passed the equivalent of a first class Navy flight physical, including complete spine X-rays and a determination of mental status Some had previous G experience, either operational or in the human centrifuge, others did not They were taking no significant medications at the time of the program, and were encouraged to eat normally, to get sufficient rest and to avoid alcoholic beverages The testing was carried out over a period of six weeks The tests were carried out on the analog computer controlled, double gimbaled dynamic flight simulator which consists of a human centrifuge having a fifty foot radius arm with the capability of attaining 40 G's in 7 seconds S M N77-11648$ Royal Air Force Inst of Aviation Medicine Farnborough (England) Biodynamics Div CENTRIFUGE ASSESSMENT OF A RECLINING SEAT David H Glaister and Brian J Lisher In AGARD The Pathophysiol of High Sustained +G sub z Acceleration, Limitation to Air Combat Manoeuvenng and the Use of Centrifuges in Performance Training Oct 1976 8 p refs Avail NTIS HC A05/MF A01 A reclining seat has been built which would give a pilot a significant increase in acceleration tolerance whilst maintaining adequate forward vision The effect of anti-G su't inflation has been investigated using three different pressure regimens, and positive pressure breathing (PPB) has been used to counter the added mspiratory effort which resulted from the considerable + G acceleration vector The reclining seat alone gave an increase in tolerance of 1 4G when compared with a conventional seat, anti-G suit inflation afforded a further 1 0 to 1 6G. and PPB a further 1 OG The combination led to relaxed greyout thresholds which averaged 7 4G in nine subjects PPB produced a significant increase in vital capacity and restored the expiratory reserve volume to near normal levels Subjectively, breathing became much easier The closing volume of the lung was increased by acceleration but was not significantly affected by PPB However the increase in expiratory reserve volume with PPB should lead to less airway closure during tidal breathing, with a consequent increase in arterial oxygen levels and a decreased susceptibility to acceleration atelectasis A seat in which a near supine position is adopted with respect to .the G vector, when used in conjunc- tion with an anti-G suit and positive pressure breathing, will result in a G tolerance which is in more accord with the performance of modern military aircraft Author N77-11649# Texas Univ Galveston Medical Branch CORONARY FLOW AND MYOCARDIAL BIOCHEMICAL RESPONSES TO HIGH SUSTAINED +G SUB z ACCELERA- TION H L Stone, L A Sordahl. R T Dowell. J N Lindsey and H H Enckson (School of Aerospace Med) In A G A R D The Pathophysiol of High Sustained +G sub z Acceleration. Limitation to Air Combat Manoeuvenng and the Use of Centrifuges in Performance Training Oct 1976 8p refs Avail NTIS HC A05/MF A01 In order to determine directly the myocardial response to +Gz acceleration, miniature swine were used as the experimental subjects Some of the animals underwent surgical implantation of flow probes around the left circumflex coronary artery and a solid-state pressure transducer in the left ventricular cavity All of the unanesthetized instrumented subjects were exposed to multiple +Gz acceleration levels for 60 to 120 seconds on a human centrifuge Other subiects were exposed to a single acceleration level for 120 seconds and the hearts removed for biochemical analysis 1 to 2 hours later Mitochondria and a lysosomal fraction were isolated from the left ventricle of all animals Mitochondria! analysis of ADP 0 ratio, respiratory control index (RCI), oxygen uptake (QO2) and calcium uptake were made Free and bound acid phosphatase measurements were made in the lysosomal fraction Left circumflex coronary artery flow (LCCF). heart rate (HR), left ventricular pressure (LVP). and the rate of rise of LVP (P), were measured in the instrumental animals LVP and HR increased-at all levels of acceleration studied while P increased initially but would decline later LCCF decreased at all levels of acceleration stress The mitochondrial AiDP 0 ratio and the RCI were unchanged but the Q02 and calcium uptake were increased at 9 + Gz Free acid phosphatase increased at the same level of acceleration Author N77-1165O# Ohio State Univ . Columbus Coll of Veterinary Medicine EFFECT OF SUSTAINED +G SUB z ACCELERATION ON CARDIAC OUTPUT AND FRACTIONATION OF CARDIAC OUTPUT IN AWAKE MINIATURE SWINE Robert L Hamlin and Sidney D Leverett, Jr (School of Aerospace Med) In AGARD The Pathophysiol of High Sustained + G sub z Acceleration Limitation to Air Combat Manoeuvenng and the Use of Centrifuges in Performance Training Oct 1976 6 p refs Avail NTIS HC A05/MF A01 Effects of sustained + Gz on cardiac rhythm and output, and on fractionation of cardiac output (CO) were studied in 12 miniature swine centnfuged while awake to either +3Gz or + 5Gz CO and its subtractions were measured by injecting radiolabeled microspheres into the left atrium Percentage of CO perfusing most organs fell precipitously during +5Gz. while that to the heart increased by twofold and that to the pelvic musculature remained nearly constant At +3Gz percentage perfusing most organs fell but that to heart and all skeletal muscle rose twofold When regional flow decreased it decreased most to the eye and next to liver, cerebrum, and renal cortex It decreased least to the midbram spleen renal medulla and gut The profound changes in CO and fractionation of CO in awake miniature swine subjected to 4-Gz may represent a summation of reflex response a waterfall effect or deformation of nutrient arteries Author N77-11651# Centre di Studi e Fttcerche di Medicina Aeronautica e Spaziale. Rome (Italy) UTILIZATION OF HUMAN CENTRIFUGE FOR TRAINING MILITARY PILOTS IN THE EXECUTION OF PROTECTIVE STRAINING MANEUVERS C A Ramacci and G Memeri In AGARD The Pathophysiol of High Sustained +G sub z Acceleration. Limitation to Air Combat Manoeuvenng and the Use of Centrifuges in Performance Training Oct 1976 3 p Avail NTIS HC A05/MF A01 The importance of the utilization of human centrifuges in the training of pilots in a rational execution of protective straining maneuvers is investigated A group of young military pilots were submitted to +Gz for comparatively long durations During the first centrifuge run the subjects were instructed to refrain from performing any voluntary straining maneuvers Later, the same subjects were submitted to the same acceleration pattern, accompanied, this tune, by the execution of the aforesaid straining maneuvers Exposures to G were repeated Changes in performance and in toleiance to G were evaluated by recording morphological changes of EXG and heart rate Subjective feelings of pilots were recorded Author 30 N77-11667 N77-11652# School of Aerospace Medicine. Brooks AFB, Tex Biodynamtcs Branch THE USE OF A FIXED BASE SIMULATOR AS A TRAINING DEVICE FOR HIGH SUSTAINED OR ACM (AIR COMBAT MANEUVERING) +G SUB z STRESS S D Leverett. Jr and R R Burton In AGARD The Pathophysiol of High Sustained +G sub z Acceleration. Limitation to Air Combat Manoeuvenng and the Use of Centrifuges in Performance Training Oct 1976 6 p refs Avail NTIS HC A05/MF A01 The imposition of +Gz stress on 92 highly experienced tactical air command fighter pilots is investigated A typical class of 22 of these pilots had an average of 1351 66 fighter hours, and were 2904 years of age (+ or - 054) In this same class of 22 Tighter pilots they estimated the highest G that they had ever pulled was + or - 9 0 Gz for 6 4 sec From this data it was apparent that fighter pilots flying the F4E Phantom |et did not pull high sustained G Therefore a centrifuge program was initiated in order to tram pilots at high sustained G and at ACM G The profile used was as follows (1) +3 Gz/15 sec - this was an orientation run m order to familiarize the pilot with the centrifuge environment, (2) +5 Gz/45 sec - this extended run was designed to enable the pilot to leam to pace his breathing and straining maneuver properly while being exposed to G sufficient to cause the anti-G suit to inflate. (3) a final ACM type profile that exposed him initially to +5 Gz/10 sec and then proceeded to +8 Gz/30 sec, decelerated to+5 Gz/10 sec and finally the centrifuge was brought to a halt Under these conditions the 92 pilots heart rate and rhythm was continuously monitored Resting heart rate for this larger group prior to initiation of the run averaged 11593 bpm While the maximum heart rate at +8 Gz was 167 04 bpm in all instances using a students t-test the P value is < 001 when the heart rates at any G level are compared to the pre-run control heart rates All of the pilots were able to complete the proposed series of runs after receiving training by 'he centrifuge group without a loss of vision Author N77-11653# EEG Research Inst, Oslo (Norway) STRESS RESPONSE AND STRESS TOLERANCE IN FIGHTER PILOTS DURING 6 G MANOEUVERS C W Sem-Jacobsen In AGARD The Pathophysiol of High Sustained +G sub z Acceleration Limitation to Air Combat Manoeuvenng and the Use of Centrifuges in Performance Training Oct 1976 6 p Avail NTIS HC A05/MF A01 EEG and EKG have been monitored from 250 active fighter pilots flying combat training involving repeated 6 G turns and pullups 50 students and 9 pilots have been monitored while riding in the back seat of two seater fighters going through the same manoeuvers More than half of those pilots who had committed pilots error were unconscious with convulsions following 6 G manoeuvers Gross EEG changes were seen in the EEG Studies of the EKG and heart rate illustrates the cardio-vascular response The well suited pilots had a quick response with increase of heart rate when needed to maintain adequate blood supply to the brain -The unsuited groups demonstrate a slow, ^insufficient cardiac response leading to brain-anoxia unconsciousness and convulsion The student pilots and the 9 pilots fell in the same two different categories indicating a basic difference in the functioning of the autonomic nervous system in these two groups Author N77-11654 Syracuse Univ NY RECEPTOR CONTRIBUTIONS TO STEADY-STATE SENSI- TIVITY IN THE PERIPHERAL RETINA OF HUMAN OBSERVERS Ph D Thesis John Miguel Martinez. II 1975 234 p Avail Univ Microfilms Order No 76-18539 Four psychophysical experiments are described which examine the role of interactions between signals from distinct receptor classes (rods and cones) in establishing steady-state sensitivity m the penpheral retina of the human eye It is found that the threshold-raising effect of a steady light field is determined by reciprocal inhibitory interactions between the rod and cone receptor systems Results indicate that the luminance difference threshold for colored light does not reflect the sensitivity of the receptor system that is most sensitive to the test wavelength employed Rather, the data suggest that increment thresholds are determined by spatial and temporal summation of mutually inhibitory rod and cone signals Interactions between receptor classes however are not found when absolute thresholds are measured This suggests a qualitative difference between the neural processes mediating absolute and difference^ thresholds in the human eye Dissert Abstr N77-11655*# National Aeronautics and Space Administration Lewis Research Center. Cleveland. Ohio POTENTIAL BIOMEDICAL APPLICATIONS OF ION BEAM TECHNOLOGY Bruce A Banks Albert J Weigand Charles A Babbush (Mt Sinai hospital Cleveland), and Craig L VanKampen (Case Western Reserve Univ) 1976 20 p refs Presented at the twelfth AIAA Intern Elec Propulsion Conf, Key Biscayne, Fla. 15-17 Nov 1976 (Grant GM-01090-14) (NASA-TM-X-73512. E-8919) Avail NTIS HC A02/MF A01 CSCL 06B Electron bombardment ion thrusters used as ion sources have demonstrated a unique capability to vary the surface morphology of surgical implant materials The microscopically rough surface texture produced by ion beam sputtering of these materials may result in improvements in the biological response and/or performance of implanted devices Control of surface roughness may result in improved attachment of the implant to soft tissue, hard tissue, bone cement, or components deposited from blood Potential biomedical applications of ion beam texturing discussed include vascular prostheses artificial heart pump diaphragms pacemaker fixation, percutaneous connectors, orthopedic pros-thesis fixtion and dental implants Author N77-11656# Johns Hopkins Univ. Baltimore, Md Dept of Biomedical Engineering PREDICTIVE MODEL OF THE AUDITORY PROCESS AS RELATED TO COMMUNICATION SYSTEMS Final Scientific Report. 1 Jan 1971 - 31 Dec 1976 M B Sachs 31 Dec 1975 12 p refs Presented at the Spring Meeting of the Acoust Soc of Am. Baltimore 1972 Submitted for publication (Contract F44620-71-C-0024. AF Proj 9777) (AD-A024300 AFOSR-76-0457TR) Avail NTIS HC A02/MF A01 CSCL 06/3 Responses from over 300 auditory nerve fibers have been systematically recorded This is the first of neural coding in avian primary fibers Recordings from single fibers in the cat auditory nerve under almost identical conditions were obtained for comparisons Aside from the different ranges of charactenstic frequencies the primary differences between avian and mammalian cochlear-nerve responses seem to be the higher rates of spontaneous and driven activity in the avian fibers Further, the investigators developed a model for relating their psychophysical results m the framework of signal detection theory which accounts for the changes in psychophysical time constant with increasing fast-tone level GRA N77-11657# Missouri Univ . Columbia THE DEVELOPMENT OF CHRONIC INSERTABLE OXYGEN ELECTRODES Annual Report Ronald E Barr Allen W Harm and Kenneth G Mayhan 25 Sep 1975 26 p (Contract DADA17-71-C-1104) ' (AO-A024633) Avail NTIS HC A03/MF A01 CSCL 06/2 An attempt is being made to develop long-term stability in oxygen sensing electrodes Suitable designs of such electrodes would then be made for long-term insertion or implantation in tissue to chronically monitor oxygen tension By employing 31 N77-11658 techniques of pretreatment and periodic anodization to a bare-tipped electrode in saline repeatable electrode operating characteristics have been obtained for over six days Investigations to obtain this type of response in biological media and in vivo conditions is being attempted, using a semipermeable membrane coating on the electrode tips to ward off poisoning A long-term in vivo electrode implantation package has been developed for use in the in vivo oxygen electrode tests Good oxygen response has been obtained for over 30 days with this system Author (GRA) N77-11658| Naval Air Development Center. Warmmster, Pa Crew Systems Dept SAFE USE OF THE P-3 STROBE LAMP Final Report Gloria Twine Chisum 22 Mar 1976 10 p refs (AD-A024036. NADC-76110-40) Avail NTIS HC A02/MF A01 CSCL 06/18 Calculations of the retinal exposure from the P-3 strobe light and safe exposure levels have been made Safe separation distances and safe use procedures are recommended Author (GRA) N77-11659# Naval Air Development Center Warmmster. Pa Crew Systems Dept THE EFFECT OF PRE-ADAPTIN6 SPECTRAL STIMULI ON VISUAL RESPONSE Gloria Twine Chisum 30 Mar 1976 27 p refs (MR041010D (AD-A024312. NADC-76085-40) Avail NTIS HC A03/MF A01 CSCL 06/16 Electroretmograms (ERGs) were recorded following pre- adaptmg exposures to radiometncally and photometrically matched spectral stimuli The magnitudes of three aspects of the ERG varied as a function of the pre-adaptmg wavelength Longer wavelength pre-adaptmg stimuli produced less suppression of the response parameters than stimuli from the short wavelength end of the spectrum The implications of the findings for display design and cockpit-light-source design and management are discussed Author (GRA) N77-11660# Naval Coastal Systems Lab, Panama City. Fla IMPROVED THERMAL PROTECTION AND REWARM PROCEDURES FOR COLD WATER DIVERS M W bppitt. Jr and G F Bond Feb 1976 86 p (AD-A024213, NCSL-271-76) Avail NTIS HC A05/MF A01 CSCL 06/19 A series of tests were made to evaluate the thermal effectiveness of variable volume dry diving suits equipped with a NASA Project Apollo urine collection device compared to SDV wet suits Six-hour dives at water temperatures from 35 F were successfully completed with no apparent problems except cold feet Breathing gas consumption oxygen consumption, and carbon dioxide production were measured during the dives which included rest and intermittent light and moderate exercise A rewarm technique involving the circulation of hot water around the torso area in a rewarm garment was evaluated using subjects in microchronic and acute hypothermia The method was found to produce a rapid return to thermal equilibrium with a small rectal temperature afterdrop Author (GRA) N77-11661# School of Aerospace Medicine Brooks AFB, Tex PRINCIPLES OF BIODYNAMICS VOLUME 3. PHYSIOLOG- ICAL MECHANISMS IN THE MAMMAL UNDERLYING POSTURE. LOCOMOTION. AND ORIENTATION IN SPACE Irving H Wagman and Willie K Dong Dec 1975 100 p refs (AF Proj 7930) (AD-A023691. SAM-Review-7-75-vol-3) Avail NTIS HC A05/MF A01 CSCL 06/19 This review describes those physiological mechanisms in the peripheral and central nervous system which underlie posture, locomotion and orientation in space Particular emphasis is given to the input-output relationships and integration of the central nervous mechanisms The mechanisms discussed involve many structures of the nervous system and are both gravity and nongravity dependent The otolith organ of the vestibular labyrinth is probably the only specific gravity sensor in the vertebrate However, gravity has a further direct effect in maintaining posture and orientation by exerting a force which results in slight stretch of the muscles of the limbs, head, and neck and thereby gives rise to reflex contractions which help maintain the body in its normal relationship in space Nongravity-dependent mechanisms, especially those involving the semicircular canals, oculomotor system, and visual system, are also of the utmost importance in supplementing the gravity-dependent mechanisms during all aspects of orientation GRA N77-11662# School of Aerospace Medicine, Brooks AFB. Tex THE EFFECT OF 1 6 GHz RADIATION ON NEUROTRANS- MITTERS IN DISCRETE AREAS OF THE RAT BRAIN Interim Report. 1 Jan - 1 Aug 1975 James H Merntt, Richard H Hartzell and James W Frazer Feb 1976 15 p refs (AF Proj 7757) (AD-A023677. SAM-TR-76-3) Avail NTIS HC A02/MF A01 CSCL 06/18 Rats were exposed to 16 GHz radiation at a measured power density of 80 mW/sq cm for 10 minutes Rectal temperature rise was 4 C Hyperthermal control rats were exposed to warm air environment to raise core temperature 4 C Hypothalamic norepmephrme was decreased in the irradiated and hyperthermal animals compared to the normothermal controls Hippocampal serotonin was decreased in the irradiated but not in the hyperthermal animals as was the dopamme content 6f the corpus striatum and hypothalamus The changes noted fit well with power distribution determined by thermographic imagery of irradiated rats and indicate that these changes are the result of the microwave-induced hyperthermia Author (GRA) N77-11663# Office of Naval Research London (England) AQUEOUS ARTEFACTS THE RIDDLE OF BOUND WATER J 8 Bateman Apr 1976 25 p refs (AD-A024643, ONRL-R-3-76) Avail NTIS HC A02/MF A01 CSCL 07/2 This paper intended for the general reader, first discusses early ideas about water binding in biological systems More recent work is presented in the form of a report and commentary on lectures given during a Royal Society discussion meeting together with occasional references to other literature and to papers given at a somewhat similar symposium in Roscoff The conclusion to be drawn is probably that although the acceptable definition of bound water is in doubt and the interpretation of experimental data frequently ambiguous, water binding to biological macromolecules to the extent of about 0 3 - 0 5 g water/g dry weight is fairly general Further, there is evidence that the rates of many biological reactions may be controlled both by direct consumptive participation and by catalytic shifts of water molecules attached in and around receptor sites A current controversy concerning the role of structured water in active transport recalls similar disputes among the earlier proponents and opponents of water binding dating probably from Overton s introduction of the idea in 1902 GRA N77-11664# Ohio State Umv Columbus Dept of Aeronautical and Astronautical Engineering CARDIOVASCULAR, RENAL AND RESPIRATORY EFFECTS OF HIGH INTENSITY. INTERMEDIATE DURATION, LOW FREQUENCY VIBRATION Interim Scientific Report. 1 Jun 1974 - 30 Jun 1975 Robert M Nerem and Robert L Hamlin 18 Jul 1975 47 p refs (Grant AF-AFOSR-2526-73. AF Proj 9777 OSURF Proj 3656-A) (AD-A025098. AFOSR-76-0545TR Rept-3656-2 ISR-2) Avail NTIS HC A03/MF A01 CSCL 06/19 A research program on the influence of high intensity, intermediate duration low-frequency wholebody vibration on the cardiovascular, renal and respiratory system is described During the period 1 June 1974 to 30 June 1975 the major emphasis 32 N77-11671 was on the in vitro study of the transport of I 131-albumin between blood and the arterial wall in the presence of oscillatory flow and pressure conditions A previous series of in vivo experiments has also been extended to include the frequencies of 6 and 14 Hz These in vivo data indicate an enhancement of albumin uptake in the dog aorta in the presence of vibration and are consistent with the in vitro data and the concept of a shear dependent transport process An in vitro study of blood-arterial wall cholesterol transport has also been initiated and in vivo measurements of aortic pressure and velocity waveforms in the presence of wholebody vibration are being continued Author (GHA) N77-11665 Colorado Univ Boulder MAJOR GENE ANALYSIS AN ALTERNATIVE APPROACH TO THE STUDY OF THE GENETICS OF HUMAN BEHAVIOR Ph D Thesis Pamela Rae Fain 1976 121 p Avail Univ Microfilms Order No 76-23607 Expectations for the relationship between sibship mean and sibship variance when a quantitative character is influenced by a major gene were derived An autosomal additive locus a locus with complete dominance a sex-linked additive locus and a sex-linked dominant were considered In every case a systematic relationship between sibship variance and sibship mean was shown to exist These patterns were confirmed in samples of data simulated to fit a number of genetic models by testing the effects of the linear, quadratic and cubic terms of sibship mean on the logarithm of sibship variance Maximum likelihood distribution analyses of simulated samples indicated that this technique may be very useful in decomposing mixtures of genotypic distributions In general, however the hypothesis that a single normal distribution also fits the data can rarely be rejected and the method may be very sensitive to unequal variance within genotypes Dissert Abstr N77-11666*# National Aeronautics and Space Administration Langley Research Center Langley Station Va AN EXPERIMENTAL STUDY FOR DETERMINING HUMAN DISCOMFORT RESPONSE TO ROLL VIBRATION Jack 0 Leatherwood, Thomas K Dempsey. and Sherman A Clevenson Nov 1976 29 p refs (NASA-TN-D-8266, L-10789) Avail NTIS HC A03/MF A01 CSCL 05 H An experimental study using a passenger ride quality apparatus (PROA) was conducted to determine the subjective reactions of passengers to roll vibrations The data obtained illustrate the effect upon human comfort of several roll-vibration parameters namely, roll acceleration level, roll frequency, and seat location (i e. distance from axis of rotation) Results of an analysis of variance indicated that seat location had no effect on discomfort ratings of roll vibrations The effect of roll acceleration level was significant, and discomfort ratings increased markedly with increasing roll acceleration level at all roll frequencies investigated Of particular interest, is the fact that the relationship between discomfort ratings and roll acceleration level was linear m nature The effect of roll frequency also was significant as was the interaction between roll acceleration level and roll frequency Author in terms of their respective data base requirements A plan of action is proposed for fulfilling the ride technology needs identified by this study Author N77-11668# Institute for Perception RVO-TNO. Soesterberg (Netherlands) S2 PROBABILITY AND CNV (CONTINGENT NEGATIVE VARIATION) R Naeaetaenen, A W K Gaillard. and S Maentysalo 1975 9 p refs (IZF-1975-11 TDCK-66921) Avail NTIS HC A02/MF A01 The relationship between the CNV and expectancy which was operationahzed as the probability of the occurrence of S2 was investigated Five withm-block probabilities were used 10 30. 50, 70 90, and 1 00 It was attempted to separate the. effects of motor preparation and expectancy by comparing the probability effect on the CNV in a reaction time task with that in a signal detection task Because largest amplitudes were obtained at sub-maximal probabilities, the CNV seems to be related more to event-uncertainty than to expectancy The results are difficult to interpret because of the low amplitudes obtained, especially in the signal-detection condition The low amplitudes are explained in two ways First, it is possible that, a motor response is a necessary condition to secure a reasonable size of CNV second, in the reaction-time task motor preparation may be suppressed by the low discnminability of S2 Author (ESA) N77-11669 Carnegie-Mellon Univ. Pittsburgh, Pa AN APPLICATION OF WIENER ANALYSIS TO HUMAN VISUAL PSYCHOPHYSICAL RESPONSE Ph D Thesis Larry Allen Abel 1976 200 p Avail Univ Microfilms Order No 76-23469 The correlation in time presented by Lee Schetzen is replaced by ensemble averaging down a set of stimulus waveforms This method of analysts is suited foe use in those areas of visual psychophysics where the input is a grating of fixed spatial extent and the output is some number corresponding to the perceived contrast of the grating Expressions for the variance of the kernel estimates produced by this technique are given Models of the contrast perception mechanism are developed in both spatial domain or single channel and frequency domain or multiple channel configurations These models were analyzed using the adapta- tion of Wiener analysis previously presented Some of the frequency domain models were also studied analytically by representing them in terms of a Taylor series expansion Dissert Abstr N77-11670*# Scientific Translation Service. Santa Barbara. Calif EQUIPMENT FOR THE COSMONAUT Ts Olegov and G Sergeyev Washington NASA Nov 1976 20 p Transl into ENGLISH from Nauka i Zhizn (USSR), no 9. Sep 1976 p 27-32 (Contract NASw-2791) (NASA-TT-F-17275) Avail NTIS HC A02/MF A01 CSCL 131 Problems are discussed for technical maintenance in space, and the instruments to be used for this purpose Methods of using these instruments under weightless conditions are also described Author N77-11667*# Boeing Co Wichita Kans USER EVALUATION OF RIDE TECHNOLOGY RESEARCH Final Report J R McKenzie and S H Brumaghim Washington NASA Nov 1976 63 p refs (Contract NAS1-13908) (NASA-CR-2746 D3-11015-1) Avail NTIS HC A04/MF A01 CSCL 05H The 23 organizations queried represent government earner, and manufacturing interests in air. manne. rail, and surface transportation systems Results indicate a strong need for common terminology and data analysis/reporting techniques The various types of ride cntena currently in use are discussed particularly N77-11671»# Umpqua Research Co. Myrtle Creek. Ore ELECTROLYTIC PRETREATMENT UNIT GASEOUS EF- FLUENT CONDITIONING Final Report Gerald V Colombo and David F Putnam Aug 1976 53 p refs (Contract NAS9-14217) (NASA-CR-151101. URC-60801) Avail NTIS HC A04/MF A01 CSCL 06B The electrolytic pretreatment of urine is an advanced process that eliminates the need for handling and storing the highly corrosive chemicals that are normally used in water reclamation systems The electrolytic pretreatment process also converts the organic materials in unne to gases (N2 and 02) that can be 33 N77-11672 used to replenish those lost to space by leakage venting, and air lock operations The electrolytic process is more than a pretreatment. since it decreases the urine solids content by approximately one third, thus reducing the load and eventual solids storage requirements of the urine processing system The evolved gases from the pretreatment step cannot, however, be returned directly to the atmosphere of a spacecraft without first removing several impurities including hydrogen, chlorine, and certain organic compounds A treatment concept was developed that would decrease the impurities in the gas stream that emanates from an electrolysis unit to levels sufficiently low to allow the conditioned gas stream to be safely discharged to a spacecraft atmosphere Two methods were experimentally demonstrated that can accomplish the desired cleanup The bases of the two methods are, repectively (1) raw urine scrubbing and (2) silica gel sorption Author N77-11672*# Life Systems, Inc. Cleveland, Ohio EVALUATION OF A SPACECRAFT NITROGEN GENERATOR Annual Status Report R D Marshall and J D Powell Sep 1976 68 p refs (Contract NAS2-8732) (NASA-CR-137930 LSI-ER-251-10-1) Avail NTIS HC A04/MF A01 CSCL 06K A method is discussed of generating nitrogen for cabin leakage makeup aboard space vehicles having longer duration missions The nitrogen generation concept is based on using liquid hydrazine as the stored form of nitrogen to reduce the higher tankage and expendables weight associated with high pressure gaseous or cryogenic liquid nitrogen storage The hydrazine is catalytically dissociated to yield a mixture of nitrogen and hydrogen The nitrogen/hydrogen mixture is then separated to yield the makeup nitrogen The excess supply of hydrogen would be available for use in the reduction of metabolic carbon dioxide A detailed comparison was completed of Palladium/Silver and Polymer Electrochemical-based Nitrogen Generation Systems The palladium/silver-based system was judged better than the Polymer Electrochemical Nitrogen Generation System because of lower expendable weight and palladium/silver nitrogen/ hydrogen separation represents off-the-shelf technology Author N77-11673*# Vought Corp , Dallas, Tex Systems Div DEVELOPMENT AND FABRICATION OF AN ADVANCED LIQUID COOLING GARMENT Final Report J R Leith and C W Hixon 22 Oct 1976 87 p refs (Contract NAS2-9026) (NASA-CR-137974. Rept-2-53230/6R-51388) Avail NTIS HC A05/MF A01 CSCL 06Q The elastomenc film fin/tube concept which was developed is a composite of polyurethane film, fine expanded silver mesh a serpentine pattern polyurethane transport tubing and an integral comfort liner, all bonded via adhesive application and vacuum- bagged for final cure As demonstrated by thermal analysis, the composite garment material is capable of removing a 293 watt (1000 BTU/hr) metabolic load through a head and torso cooling area of 46 sq m (5 sq ft) with tube spacing of slightly under one inch A total of 60 test elements, each 15m x 15m (6 in x 6 in) were fabricated in support of the liquid cooling garment concept development In parallel with the fabrication of these elements a continuing series of laboratory tests to support the fabrication techniques was earned out The elements and supporting tests are described Author N77-11674*jjl National Aeronautics and Space Administration Ames Research Center, Moffett Field, Calif PILOT WORKLOAD AND FATIGUE- A CRITICAL SURVEY OF CONCEPTS AND ASSESSMENT TECHNIQUES Walter B Gartner (Adex Systems) and Miles R Murphy Washington Nov 1976 60 p refs (NASA-TN-D-8365. A-6630) Avail NTIS HC A04/MF A01 The principal unresolved issues in conceptualizing and measuring pilot workload and fatigue are discussed These issues are seen as limiting the development of more useful working concepts and techniques and their application to systems engineering and management activities A conceptual analysis of pilot workload and fatigue, an overview and critique of approaches to the assessment of these phenomena, and a discussion of current trends in the management of unwanted workload and fatigue effects are presented Refinements and innovations in assessment methods are recommended for enhancing the practical significance of workload and fatigue studies Author N77-11676*# National Aeronautics and Space Administration Lyndon B Johnson Space Center Houston, Tex ASTP CHEMICAL AND MICROBIOLOGICAL ANALYSIS OF POTABLE WATER Richard L Sauer and Scott A Leslie Oct 1976 12 p refs (NASA-TM-X-58192. JSC-11578) Avail NTIS HC A02/MF A01 CSCL 06K The Apollo-Soyuz Test Project procedures for potable water system servicing and the results of preflight and postflight chemical and microbiological analyses of the water are discussed Tables show results of the analyses The effectiveness of the water system is evaluated Author N77-11676*# Umpqua Research Co. Myrtle Creek, Ore DEVELOPMENT ASSESSMENT OF WASH WATER RECLA- MATION Final Report David F Putnam Aug 1976 90 p refs (Contract NAS2-8239) (NASA-CR-137934. URC-60806) Avail NTIS HC A05/MF A01 CSCL 06K An analytical study assessment of state-of-the-art wash water reclamation technology is presented It covers all non-phase- change unit operations, unit processes and subsystems currently under development by NASA Each approach to wash water reclamation is described in detail Performance data are given together with the projected weights and sizes of key components and subsystems It is concluded that a simple multifiltration subsystem composed of surface-type cartridge filters carbon adsorption and ion exchange resins is the most attractive approach for spacecraft wash water reclamation in earth orbital missions of up to 10 years in duration Author N77-11677*jjl Energy Research Corp Danbury, Conn DEVELOPMENT OF A PROTOTYPE REGENERABLE CAR- BON DIOXIDE ABSORBER Michael Onischak 10 Sep 1976 26 p refs (Contract NAS2-8644) (NASA-CR-137919) Avail NTIS HC A03/MF A01 CSCL 06K Design information was obtained for a new. regenerate carbon dioxide control system for extravehicular activity life support systems Solid potassium carbonate was supported in a thin porous sheet form and fabricated into carbon dioxide absorber units Carbon dioxide and water in the life support system atmosphere react with the potassium carbonate and form potassium bicarbonate The bicarbonate easily reverts to the carbonate by heating to 150 deg C The methods of effectively packing the sorbent material into EVA-sized units and the effects of inlet concentrations, flowrate and temperature upon perform- ance were investigated The cycle life of the sorbent upon the repeated thermal regenerations was demonstrated through 90 cycles Author N77-11678# Committee on Science and Technology (U S House) CREW TRAINING AND SUPPORT ACTIVITIES Washington GPO 1976 49 p Hearing before Subcomm on Space Sci and Applications of Comm on Sci and Techno!, 94th Congr, 2d Sess, 22 Jun 1976 (GPO-75-984) Avail Subcomm on Space Sci and Applications The current, status of crew training for the space shuttle program is briefly reviewed J M S 34 N77-11685 N77-11679# Stanford Univ , Calif Dept of Civil Engineering CONTINUING RESEARCH IN THE DEVELOPMENT OF INTERACTIVE MAN-COMPUTER SYSTEMS FOR ENGI- NEERING-CONSTRUCTION PROJECTS Final Report. 1 Apr 1974 - 30 Sep. 1976 Boyd C Paulson. Jr Sep 1975 68 p refs (Gram NSF GK-42132) (PB-252927/9. TR-200 NSF/GK-42132/SU-TR-200) Avail NTIS HC A04/MF A01 CSCL 13B An interactive man-computer environment is reported to develop implement and test hypotheses and systems involving integrated network models for the planning and control of resources and operations on large engineering-construction projects Examples include rapid transit systems, nuclear power plants, and mining developments GRA N77-11680$ Virginia Polytechnic Inst and State Univ, Blacksburg Dept of Industnal Engineering and Operations Research COMPUTERIZED ANALYSIS OF EYE MOVEMENTS DURING STATIC DISPLAY VISUAL SEARCH Interim Report. Jun 1973 - Apr. 1975 Harry Snyder and Donald F Taylor Wright-Patterson AFB. Ohio AMRL Feb 1976 78 p refs (Contract F33615-71-C-1739 AF Pro) 7183) (AD-A024100. AMRL-TR-75-91) Avail NTIS HC A05/MF A01 CSCL 17/8 A computerized analysis technique was developed for the evaluation of eye movements This technique, when applied to eye movement data of 1 millisecond temporal resolution, is considered useful to evaluate such eye movement parameters as fixation duration, mterfixation distance, and number of fixations per tnal This analysis technique was evaluated for displays having a single target and up to 192 nontargets in a static display The results indicate that fixation duration is unaffected by the density of nontargets, but that the mean mterfixation distance decreases linearly with increases in nontarget density Due to this decrease in mterfixation distance, the search time and the number of fixations per trial increase linearly with the density of nontargets An overall evaluation of the eye movement measuring device is offered Author (GRA) N77-11681# GCA Corp, Bedfqrd. Mass Technology Oiv DESIGN, DEVELOPMENT. FABRICATION AND TESTING OF A PORTABLE SELF-CONTAINED RESPIRABLE DUST MASS MONITOR Pedro Ulienfeld 25 Oct 1974 58 p refs (Contract H0232039) (PB-254503/6. BM-OFR-73-76) Avail NTIS HC A04/MF A01 CSCL 14B An airborne mass monitor for unattended and recording measurements of the concentration of dust in mining environments is described Sensing collection are performed by beta-radiation attenuation and inertia! implementation respectively The instrument is portable, battery or line operated provides a digital printout of the mass concentration during each selection sampling penod. as well as the accumulated mass of dust and the elapsed sampling time GRA N77-11682# Frankford Arsenal. Philadelphia, Pa REDUCTION OF TARGET DETECTABILITY BY LASER PROTECTIVE MATERIALS Gerald C Hoist Apr 1976 22 p refs (DA Proj 1T1-61102-AH-46) (AD-A024383. FA-TR-76021) Avail NTIS HC A02/MF A01 CSCL 05/5 An ideal laser protection material will provide the required optical density at the laser wavelength and be transparent at all other wavelengths Although there are many ways to formulate a quality factor, the present study examines a method of combining luminous transmission with the detectabihty of low contrast targets The present study examines how detectabihty of low contrast targets is affected by two popular ruby laser protectors In order to study the effect of color rendition only, neutral density filters were used to equate the luminous transmission of the two goggles Theoretical considerations of how these goggles might perform is given to obtain the effects of protective materials on detectabihty, the contrast required for the detection of various achromatic targets was measured The targets consisted of fourteen gratings which subtended visual angles from 2 26 minutes per line pair up to 68 4 minutes per line pair GRA N77-11683# Honeywell, Inc Minneapolis Minn Systems and Research Center DYNAMIC CONTRAST REQUIREMENTS Final Report Leon G Williams and Judith M Enckson Feb 1976 93 p refs (Contract N00014-74-C-0076 NR Proj 215-229) (AD-A023973 Rept-76-SRC/6. ONR-CR215-229-2F) Avail NTIS HC A05/MF A01 CSCL 05/5 Three expenments were conducted to investigate the spatial and temporal relationship between the human visual system and displayed imagery In Expenment I. contrast sensitivity for sinusoidal gratings was determined as a function of spatial frequency, temporal frequency, luminance and stimulus position on the retina In Experiment II contrast sensitivity for sinusoidal gnds was determined as a function of the horizontal and vertical spatial frequency, and temporal frequency In Experiment III. sinusoidal grating targets on grating surrounds were used to determine contrast sensitivity as a function of target spatial frequency, surround spatial frequency and temporal frequency The data from the three experiments indicate how much contrast is required under specified conditions to just detect a noise-free target defined in terms of its spatial and temporal frequency content The results provide a means for predicting the visibility of targets in real displays GRA N77-11684# Human Engineering Labs Aberdeen Proving 'Ground Md ° INFLUENCE OF PILOT INCAPACITATION ON LOW SPEED AND HOVERING FLIGHT Final Technical Report Douglas P Harvey and John D Waugh Jan 1976 37 p refs (AD-A023728, HEL-TM-7-76) Avail NTIS HC A03/MF A01 CSCL 05/5 Very little quantitative information exists as to survivabihty of a lone or surviving helicopter pilot who is incapacitated by wounds received during a mission Since the pilot normally uses all four limbs, his ability to maintain control of an otherwise flyable aircraft is expected to be impaired A safe yet realistic approach to the investigation was to physically restrain single hands, limbs, etc of Army aviators hovering a DHT-1 Whirlymite Tramer--a semitethered but otherwise genuine single-place helicopter The relative accuracy with which subjects followed a prescribed flight path under the restraints was the primary means of comparison Statistical analysis of integrated error scores showed that the only effective restraints were those involving an entire limb Since this investigation only involved hovering flight recommendations included further work in cruise considera- tions in favor of multiple-limb restraints GRA N77-11685# Michigan Univ Ann Arbor Mental Health Research Inst TARGET DETECTION IN RAPIDLY-CHANGING VISUAL SEQUENCES Final Report Irwm Pollack Mar 1976 32 p refs (Contract N00014-67-A-0181-0051. NR Pro) 197-022) (AD-A023784) Avail NTIS HC A03/MF A01 CSCL 05/10 Sequences of digits were painted upon a display scope under conditions of a stationary window (window fixed moving sequence) and of a moving window (sequence fixed, moving window) Performance was examined under a variety of window-sizes and rates of presentation Unlike the reading of English text with long-term sequential constraints, the present task could be specified by only two successive digits Nevertheless, the accuracy of target detection improved with window size m a manner not unlike that reported for English text The results are discussed GRA 35 N77-11686 N77-11686# Systems Research Labs Inc. Dayton, Ohio COMPARISON OF HUMAN INFORMATION PROCESSING PERFORMANCE WITH DOT AND STROKE ALPHABETIC CHARACTERS Interim Report. Jan 1974 - Jun 197S Robert D ODonnell and Frank E Corner Jan 1976 23 p refs (Contract F33615-72-C-0235 AF Pro) 7184) (AD-A024099. AMRL-TR-75-95) Avail NTIS HC A02/MF A01 CSCL 05/5 Recent engineering developments have stimulated interest in the use of displays which will present alphanumeric information in dot format In order to supply human factors data on how information presented in punctate form is processed, the Sternberg item recognition procedure was used and discrimination reaction time (RT) to both dot and stroke letters was determined under various amounts of memory load In addition, the visually evoked response (VER) of the electroencephalogram was recorded during RT performance and compared as a function of symbology format These results suggest that dot letters require slightly longer (less than 10 msec) to encode than stroke letters However, subsequent to about 200 msec after the letter is presented no statistically significant differences appear in either RT or VER data suggest- ing that once the letter is encoded it is processed equally well whether the original format was dot or stroke In addition, no evidence of increased work load greater errors, or other performance decrement was seen with the dot format used here Under the conditions tested subjects were apparently able to compensate for the additional encoding time with little effort and with no demonstrable effect on overall performance GRA N77-11687# Illinois Univ, Urbana Aviation Research Lab ENHANCEMENT OF HUMAN EFFECTIVENESS IN SYSTEM DESIGN. TRAINING. AND OPERATION JULY 1974 - JUNE 1975 Final Report Stanley N Roscoe and Charles 0 Hopkins Jul 1975 35 p refs (Contract F44620-70-C-0105 AF Proj 9778) (AD-A023941 ARL-75-21/AFOSR-75-10 AFOSR-76-0476TR) Avail NTIS HC A03/MF A01 CSCL 05/8 This report is part of a study on residual attention, information load and pilot performance It has resulted in (1) General rules and prediction equations for evaluation Of task load and operator efficiency, (2) Discrimination of individual differences in attention and assessment of their predictive validity to operational performance (3) Development of training procedures for timesharing and (4) Application of feedback control theory to operator tracking performance in timesharing Investigation of adaptive logic in acquisition of perceptual-motor skills included a review of literature on adaptive training with emphasis on current theoretical models of perceptual motor skills Experiments were designed to investigate the role of propnoceptive and visual response-produced feedback during motor learning and the effects of changing response-produced feedback after the same or after different amounts of practice GRA control strategies that can be generalized to the more complex arms Various approaches are taken towards trajectory optimiza- tion An optimal feedback control scheme is developed for this arm and is generalizable to the six-degrees-of-freedom robot arm GRA N77-11689# Pntsker and Associates, Inc West Lafayette Ind SAINT II DOCUMENTATION MANUAL Final Report David B Wortman. C Elliott Sigal, A Alan B Pntsker and Deborah J Seifert Wright-Patterson AFB, Ohio AMRL Dec 1975 229 p refs (Contract F33615-74-C-4005. AF Proj 7184) (AD-A024286, AMRL-TR-75-116. AMRL-HESS-74-4) Avail NTIS HC A11/MF A01 CSCL 05/5 A network modeling and analysis technique called SAINT II has been developed to model and analyze complex Air Force man-machine systems The modeling vehicle developed is a set of network symbols and terminology and the analysis vehicle is compute) simulation SAINT 2 obtains system performance measures for networks that represent a mission consisting of a set of tasks performed by a crew of operators having a complement of equipment in the face of environmental factors These system performance measures are obtained via a simulation approach Human engineering considerations are reflected in the modeling technique by means of task parameter specifications, task precedence and sequencing relations and psycho-social and environmental factors affecting crew performance This report describes the SAINT 2 simulation program, which includes a number of new capabilities not available in the original SAINT program GRA N77-11688# Illinois Univ Urbana Coordinated Science Lab CONTROL AND TRAJECTORY OPTIMIZATION OF A ROBOT ARM Kar-Keung David Young Nov 1975 218 p refs Sponsored in part by NSF (Contract DAAB07-72-C-0259. Grant AF-AFOSR-2570-73) (AD-A023669, R-701, UILU-ENG-75-2236) Avail NTIS HC A10/MF A01 CSCL 06/4 In the past few years robot arms or computer-controlled manipulators have been developed in several Artificial Intelligence research laboratories in the United States The purpose of designing and building these robot arms is to use them as devices to perform physical tasks The movements of the robot arms are required to be similar to humans' Conventional positioning servos implemented on industrial robots are no longer applicable This study concentrates on finding optimal arm trajectories and possible control strategies for a two-link robot arm whose motion is confined to the vertical plane As the mathematical model for a six-degrees-of-freedom robot arm is highly nonlinear, it is intended to first investigate a simpler arm and hopefully develop 36 SUBJECT INDEX AEROSPACE MEDICINE AND BIOLOGY / A Continuing Bibliography I Suppl 164 I* F E B R U A R Y 1977 Typical Subject Index Listing SUBJECT HEADING B1DIOBIOLOGI -Experiments aboard biosatellites Kosios-690 and Kos.os-782 biological effect of solar and galactic radiation [B4S4-TT-F-172151 H77-107B2 The title is used to provide a description of the subject matter When the title is insufficiently descriptive of the document content a title extension is added separated from the title by three hyphens The NASA or AIAA accession number is included in each entry to assist the user in locating the abstract in the abstract section of this supplement If applicable a report number is also included as an aid in identifying the document ABSOBBBHTS Development of a prototype regenerable carbon dioxide absorber [N4S4-CB-137919-] N77-11677 ABSOBBEBS (HATEBIALS) Development of a prototype regenerable carbon dioxide absorber [NASA-CB-137919] 1177-11677 4CCELEB4TIOH (PHYSICS) Ventricular pathology in swine at high sustained *G sub z N77-11646 Psycho-physiological and physio-chemical assessment of acceleration induced changes in humans positioned in various seatback angle configurations 1177-11647 Coronary flow and myocardial biochemical responses to high sustained +G sub z acceleration N77-11649 ACCBLBBATIOH SIBESSES (PHYSIOLOGY) Prevention of experimental motion sickness by scopolamine absorbed through the skin 477-10064 Biophysical analysis of the action of Coriolis acceleration on the vestibular analyzer 477-10652 Evaluation of the effect of impact accelerations on the organism froa laboratory data 477-11352 Effect of accelerations, additional weight stress, and hypokinesia on protein metabolism in the Japanese guail /Coturnix coturnix 3aponica/. I - Effect on muscle composition 477-11353 Human tolerance to + Gz accelerations during heating of the body 477-11358 Adaptation of the cardiovascular system to negative stressful acceleration during repeated antiorthostatic exposures 477-11361 Dynamics of the motor components of the optokinetic nystagmus during exposure of the vestibular apparatus to angular accelerations 477-11371 Effect of transverse accelerations on the motor function of the stomach 477-11376 Hethods for studying the tolerance of pilots to inflight acceleration 477-11417 Functional state of the layer-pancreas system during exposure to low transverse accelerations 477-11427 Besponses of external respiration to *8 Gx overload for different training level of testees 477-11465 The pathophysiology of high sustained +G sub z acceleration. Imitation to aic combat manoeuvering and the use of centrifuges in performance training [AGABD-CP-189] H77-11644 Effect of sustained »G sub z acceleration on cardiac output and fractionation of cardiac output in awake miniature swine H77-11650 4CCELEBATIOS TOLEBABCE Effect of hypovolemia, infusion, and oral rehydration on gradual onset +Gz acceleration tolerance [IAF PAPEB 76-039] A77-10888 Tolerance to +Gz acceleration of pilots with a tendency toward hypotensive responses under hot climate conditions 477-11435 Some responses of man to prolonged centripetal accelerations /+Gz/ of small values 477-11436 Centrifuge assessment of a reclining seat N77-11648 Utilization of human centrifuge for training military pilots in the execution of protective straining maneuvers 1177-11651 4CIDS Effect of orotic acid on weight dynamics in rats subjected to restrained motor activity 477-11463 ACTIVITY (BIOLOGY) First results of an investigation of the effects of microwave radiation with low power density on the behavior of rats [H8L-1974-15] N77-10778 ADAPTATI08 Cognitive activity of man during adaptation to short-term weightlessness 477-11360 Cellular and molecular aspects of adaptation 477-11430 ADBHOSISE TEIPHOSPHSTE A model of the physiological thermoregulation system 477-11391 ADHKSIOS IESTS Determination of the adhesion properties of foodstuffs 477-11384 ADBESAL HBT4BOLISH 4drenal function in man during exposure to a hyperbaric environment for many days /N2-O2, 5 atm/ 477-11410 4DBENOCOBIICOIBOPIH (ACTH) Effect of hydrocortisone and adrenocorticotropin on the conformational state of proteins in the brain and muscles 477-10661 AEBOSPACB HEDICIHE Transportation in commercial aircraft of passengers having contagious diseases 477-10067 Ultrasonic Doppler cardiography in the medical control system 477-11399 1-1 IIB POLLOTIOH SUBJECT IHDEI On the expert diagnostic value of physiological para»eters for objective monitoring of a pilot's condition in flight A77-11404 Comparative characterization of electrocardiograns in flight personnel mth normal and excessive weight under moderate hypoxia 477-11416 Preliminary results of medical studies during the flight of the second expedition of the Salyut 4 orbital station A77-11450 The possibilities of Spacelab for solving nedical problems A77-11589 Psycho-physiological and physio-chemical assessment of acceleration induced changes in humans positioned in various seatback angle configurations N77-11647 The use of a fixed base simulator as a training device for high sustained or ACH (Air Combat Maneuvering) *G sub z stress H77-11652 AIB POLLUTION Relations of the hydroxyproline concentration in the lungs to the lung Height, the silica and aluminum concentrations, and the dust dose, after repeated intratracheal coal dust application in a long-term test vith rats 477-12288 Design, development, fabrication and testing of a portable self-contained respirable dust mass monitor (PB-254503/6] N77-11681 AIB PORIFIC4TIOS Physicochemical purification of the gas-vapor phase formed during dessication of solid waste from human vital activity 477-11449 1IBCBAFT LAHDIHG Readability of approach charts as a function of visual acuity, luminance, and printing format A77-10051 AIBCBAFT MANEUVERS The pathophysiology of high sustained + G sub z acceleration, limitation to air combat manoeuvering and the use of centrifuges in performance training [AGABD-CP-189] H77-11644 The use of a fixed base simulator as a training device for high sustained or ACH (Air Combat Maneuvering) +G sub z stress N77-11652 Stress response and stress tolerance in fighter pilots during 6 G manoeuvers N77-11653 AIBCBAFI NOISE Subjective response to combined noise and vibration during flight of a large twin-jet airplane [NASA-TM-I-3406] N77-10790 AIBCBAFT PILOTS Psychomotor test performance and sleep patterns of aircrew flying transmeridional routes A77-10600 Clinicophysiological studies of pilots with first stage hypertension • A77-11398 On the expert diagnostic value of physiological parameters for objective monitoring of a pilot's condition in flight 477-11104 Tolerance to +Gz acceleration of pilots with a • tendency toward hypotensive responses under hot climate conditions A77-11435 Stress response and stress tolerance in fighter pilots during 6 G manoeuvers N77-11653 AIBCBAFT SAFETY Food sanitation and air safety 477-10066 AIRLINE OPERATIONS Effects of rapid round trips against time displacement on adrenal cortical-medullary circadian rhythms 477-10065 Food sanitation and air safety 477-10066 ALBDHIHS Measurement of change in plasma volume during heat exposure and exercise 47,7-10053 ALGAE Investigation of the physiological activity of chlorella vulgaris following an exposure to space flight factors aboard the Salyut orbital station 477-11355 Model of an ecological system closed relative to gas exchange with a periodically operating autotrophic unit. II - Stability of periodic cycles 477-11357 ALKABES Honocarboxylic acids from oxidation of acyclic isoprenoid alkanes by Hycobacterium fortnitum A77-10705 ALPHA PARTICLES Effect of alpha radiation on Chlorella vulgaris at different stages of cellular cycle A77-11422 ALPHABETS Comparison of human information processing performance with DOT and stroke alphabetic characters [AD-A024099] N77-11686 ALTITUDE 4CCLIH4TIZATIOM Responses of the autonomic nervous system during acclimatization to high altitude in man 477-10060 Dorking capacity of man during stay at high altitudes 477-11364 The effect of different regimes of motor activity on the adaptation of man to high altitude 477-11371 Human cardiovascular responses to orthostatic tests after highland adaptation 477-11438 Periods of retainment of increased general resistance of the organism under different conditions of adaptation to oxygen deficiency 477-11458 ALTITUDE SICKHKSS Prevention of decompression sickness as related to repeated extravehicular activities 477-11408 Dynamics of changes in the galvanic skin response in man during altitude decompression 477-11429 4LTITODB SIHOLATIOH Changes in the monosynaptic H-response of man during altitude decompression 477-11407 Prevention of decompression sickness as related to repeated extravehicular activities 477-11408 AL7EOLAB 416 Cyclic hypoxic pulmonary vasoconstriction induced by concomitant carbon dioxide changes 477-11098 AMINES Radioprotective effect of mexamin and cystamin on animals exposed to hypokinesia and ionizing radiation 477-11366 AMIHO ACIDS Free ammo acids in human blood plasma during space flights 477-10057 Diagnostic significance of free ammo acid content in the blood plasma during dietary protein deficiency in man 477-11441 ANAEROBES Investigation of the biological properties of type-4 Cl. perfringens released in persons placed in a hermetic chamber 477-11419 4HGDL4B ACCELERATION The effect of centrifugal force on the neck nystagmus of pigeons A77-11373 1-2 SUBJECT IHDEX AODITOBI TASKS Dynamics of the notor coaponents of the optokinetic nystagmus daring exposure of the vestibular apparatus to angular accelerations A77-11374 4BIOAL VABIATIOHS Average latitudinal variation in ultraviolet radiation at the earth's surface biological sensitivity and dosage A77-10991 AHTHBACBHE The contraction prolonging action of 9-anthroic acid (ANCA) on the isolated rat diaphragn and the effects of soman on this phenomenon [HBL-1975-25] 1177-10779 AHTIBODIES Aotitissular antibodies and complenent in hypokinesia A77-11402 AHIIBADIATIOH DBDGS Badioprotective effect of mexamin and cystamin on animals exposed to hypokinesia and ionizing radiation A77-11366 ANTISEPTICS Virion aggregation and disinfection of water viruses by bromine [PB-253087/1 ] N77-11642 AOBTA The posterior aortic wall echocardiogram - Its relationship to left atrial volume change A77-11049 APOLLO SOYOS TEST PROJECT Joint inflight bionedical experiments performed during the ASTP spaceflight bacteriological experiments [IAF PAPEB 76-031] A77-10887 The Soyuz-Apollo experimental flight - Preliminary results of medico-biological research carried out during flight of Soyuz-19 A77-11369 Bioprocessing in space [BASA-TtJ-I-74157] N77-10777 ASTP chemical and microbiological analysis of potable water [HASA-TH-X-58192] N77-11675 AQDIFEES Development assessment of wash water reclamation [NASA-CB-137934J N77-11676 ABB (ABATOHI) Control and trajectory optimization of a robot arm [AD-A023669] B77-11688 ABTEBIOSCLEBOSIS Hegglin's syndrone in flight personnel with atherosclerotic coronary cardiosclerosis and its clinical evaluation A77-11445 Hedical screening of flight personnel in certain types of chronic diseases of the myocardium A77-11461 ABIIFICIAL GBAVIIT Eye movements occurring during head turns aboard artificial gravity stations A77-11351 Some responses of man to prolonged centripetal accelerations /*Gz/ of snail values A77-11436 ASIBOBADT PEBFOBBASCB Hedical experiment H-171 - Besults from the second manned Skylab mission A77-10056 Free ammo acids in human blood plasma during space flights A77-10057 Effects of head-down tilt on fluid and electrolyte balance A77-10058 in automated miniaturized Haploscope for testing binocular visual function A77-10147 Some principles for the recovery of central vision after temporary blindness A77-11414 Dependence of human body weight loss on space flight duration A77-11415 Evaluation and application of the quantitative indices of the quality of operator work in spacecraft control A77-11418 Preliminary results of medical studies during the flight of the second expedition of the Salyut 1 orbital station A77-11450 Orthostatic tolerance of cosmonauts after 30- and 63-day flights onboard the orbital base Salyut-4 A77-11451 Cardiorespiratory responses of cosmonauts to graded physical work after 30- and 63-day flights aboard the orbital base Salyut-4 A77-11452 Theoretical aspects of the problem of predicting the state of the human organism during space flight A77-11453 Genesis of vestibulo-vegetative disorders under weightlessness conditions A77-11466 ASTBOBAOT TBAIBIHG Shuttle crew training revision needed A77-11546 ASTBOBAOTS Equipment for the cosmonaut [HASA-TT-F-17275] S77-11670 AIE1ECTASIS Centrifuge assessment of a reclining seat H77-11648 4DDIOHETBY Influence of the peak pressure and duration of impulse noise (gun fire) on the hearing of the guinea pig [ISL-H-109/75] H77-11639 ADDIIOBI FATIGUE Influence of the peak pressure and duration of impulse noise (gun fire) on the hearing of the guinea pig [ISL-B-109/75J N77-11639 ADDITOBI PEBCEPTIOH Influence of auditory fatigue on masked pure-tone thresholds A77-10137 Simultaneous three-channel signal detection - Performance and criterion as a function of order of report auditory perception tasks A77-11166 Functional interdependence of the visual and auditory analyzers during extremal stimulation A77-11362 Evaluation of the rate of acoustic reception of radiotelegraph signals in psychological selection of candidates for pilot training A77-11394 Influence of a precursor noise on the global action potential consecutive to an impulse noise in the Guinea pig [ISL-B-115/75] H77-11640 Predictive model of the auditory process as related to communication systems [AD-A024300] 1177-11656 AODITOBI SIGBALS Simultaneous three-channel signal detection - Performance and criterion as a function of order of report auditory perception tasks A77-11166 ADDITOBI STIHOLI Beyond averaging - The use of discriminant functions to recognize event related potentials elicited by single auditory stimuli A77-11749 Influence of the peak pressure and duration of impulse noise (gun fire) on the hearing of the guinea pig [ISL-B-109/75] H77-11639 Study of metabolic response variation to an acoustic aggression metabolic recuperation after sonic boom H wave exposure [ISL-B-120/75] 1177-11641 52 probability and CSV (Contingent Negative Variation) signal detection task and selective reaction time task [IZF-1975-11] H77-11668 AODIIOBI TASKS Simultaneous three-channel signal detection - Performance and criterion as a function of order of report auditory perception tasks A77-11166 1-3 AUTOMATIC TEST EQUIPBEHT SUBJECT IKDEI AUTOMATIC TEST EQUIPHEHT 4 computer program for the use of sensitivity analysis in display evaluation '[NASA-CR-1U5060] N77-10793 AUTOH08IC NERVOUS SISTER Responses of the autonomic nervous system during acclimatization to high altitude in man A77-10060 AOTOTBOPHS Hodel of an ecological system closed relative to gas exchange with a periodically operating autotrophic unit. II - Stability of periodic cycles A77-11357 BACTERIA Monocarboxylic acids from oxidation of acyclic isoprenoid alkanes by Hycobacterium fortuitum 477-10705 Analytical notes - Electrochemical method for early detection and monitoring of coliforms A77-10988 BACTBRICIDBS An evaluation of a fuel-soluble organoboron biocide for control of sulfate-reducing bacteria in shipboard fuel tanks [AD-A02U017] N77-11643 BACTERIOLOGY Halobacterium saccharovorum sp. nov., a carbohydrate-metabolizing, extremely halophilic bacterium A77-10702 Light-induced membrane potential and pH gradient in Halobacterium halobium envelope vesicles A77-10703 Light-induced glutamate transport in Halobacterium halobium envelope vesicles. II - Evidence that the driving force is a light-dependent sodium gradient A77-10704 Joint inflight biomedical experiments performed during the ASTP spaceflight bacteriological experiments [IAF PAPER 76-031] A77-10887 Investigation of the biological properties of type-A Cl. perfringens released in persons placed in a hermetic chamber A77-11119 BABOBECEPTOBS Cerebellar pressor response in the dog A77-11100 BAIES THEOBBH Ridge and Bayes identification for the guasilinear human controller in compensatory tracking A77-10123 BIHOCOLAB VISIOB An automated miniaturized Haploscope for testing binocular visual function A77-10147 Bivalrous texture stereograms binocular fusion explained by spatial-frequency-tuned channels A77-11999 BIOASSAI Studies on the nature of plasma growth hormone A77-10700 BIOASTROHADTICS Joint inflight biomedical experiments performed during the ASTP spaceflight bacteriological experiments [IAF PAPER 76-031] A77-10887 Some responses of man to prolonged centripetal accelerations /+Gz/ of small values A77-11136 The possibilities of Spacelab for solving medical problems A77-11589 BIOCBBHICAL OIIGEB DEHAHD Coronary flow and myocardial biochemical responses to high sustained +G sub z acceleration H77-116U9 BIOCHBglSTBI Honocarboxylic acids fro» oxidation of acyclic isoprenoid alkanes by Hycobacteriuo fortuitum A77-10705 Effect of orotic acid on weight dynamics in rats subjected to restrained motor activity A77-11U63 Photoreceptor membrane carbohydrate on the intradiscal surface of retinal rod disks A77-11476 BIOCONTBOL SYSTEMS Cerebellar pressor response in the dog A77-11100 A model of the physiological thermoregulation system A77-11391 Cellular and molecular aspects of adaptation A77-11430 A mathematical model of the human temperature regulatory system - Transient cold exposure response A77-12244 BIODYNAMICS Ultrasonic Doppler cardiography in the medical control system 477-11399 Biodynamics of deformable human body motion D77-10260 Principles of biodynamics. Volume 3: Physiological mechanisms in the mammal underlying posture( locomotion, and orientation in space [4D-A023691] N77-11661 BIOELECTRIC POTBHTIAL Light-induced membrane potential and pH gradient in Halobacterium halobium envelope vesicles 477-10703 BIOELECTRICITI Beyond averaging - The use of discriminant functions to recognize event related potentials elicited by single auditory stimuli 477-11749 BIOENGIHEEBIHG Biolized latex polyurethanes [PB-253085/5] 1177-10786 BIOINSTBUMEHTATIOH Determination of oxygen tension by measurement of net charge transport 477-12245 A system of remote utilization of a computer during the processing of biological data 477-12379 Thermistor holder for skin temperature measurements [NASA-CASE-ARC-10855-1] H77-10780 Development and evaluation of an ultrasonic imaging system [PB-252561/6] H77-10788 Potential biomedical applications of ion beam technology [HASA-TB-X-73512] H77-11655 BIOLOGICAL EFFECTS Average latitudinal variation in ultraviolet radiation at the earth's surface biological sensitivity and dosage A77-10991 The effect of a long-time influence of a constant and alternating 1000-oersted magnetic field on mitotic activity A77-11396 Investigation of the biological effect of vibration on plants A77-114<13 Experiments aboard biosatellites Kosmos-690 and Kosmos-782 biological effect of solar and galactic radiation [NASA-TT-F-17215] H77-10782 BIOBEDICAL DATA The Sofuz-Apollo experimental flight - Preliminary results of medico-biological research carried out during flight of Soyuz-19 A77-11369 State of vascular regulation and regional hemodynamics in Soyuz-12 and Soyuz-13 crevmembers before and after flight A77-11388 On the expert diagnostic value of physiological parameters for objective monitoring of a pilot's condition in flight A77-11itO Primitive grain clumps and organic compounds in carbonaceous chondrites A77-11997 OBTHOPBDICS Potential biomedical applications of ion beam technology [NASA-TM-X-73512] N77-11655 OBTHOSTATIC TOLBB4BCB Effects of head-down tilt on fluid and electrolyte balance 477-10058 Antiorthostatic hypokinesia as a method of weightlessness simulation 477-10062 Adaptation of the cardiovascular system to negative stressful acceleration during repeated antiorthostatic exposures 477-11361 Human cardiovascular responses to orthostatic tests after highland adaptation 477-11438 Orthostatic tolerance of cosmonauts after 30- and 63-day flights onboard the orbital base Salyut-4 477-11151 OXIGEH Electrolytic pretreatment unit gaseous effluent conditioning [NASA-CB-151101] H77-11671 OXIGEH BBE4THIHG Intracerebral oxygen and carbon dioxide tensions in the rhesus monkey 477-10055 OXIGEB COHSDHPTIOH The influence of the position of the oxygen dissociation curve on oxygen-dependent functions of the isolated perfused rat liver. II - Studies at different levels of hypoxia induced by decrease of blood flow rate 477-10223 OXIGEB TBBSIOI Intracerebral oxygen and carbon dioxide tensions in the rhesus monkey 477-10055 Influence of hyperoxia on the characteristics of external respiration, cardiovascular system, and gas composition of blood A77-11393 1-18 SDBJECI ISDEI PHYSIOLOGICAL BESPOBSES Determination of oxygen tension by measurement of net charge transport A77-1224S The development of chronic insertable oxygen electrodes [AD-A024633] H77-11657 OIYGEBiTIOB Monocarboxylic acids from oxidation of acyclic isoprenoid alkanes by oycobacterium fortnitum A77-10705 PAID SBSSITIVITY Lack of effect of naloxone on pain perception in humans A77-11475 PABCBEiS Functional state of the liver-pancreas system during exposure to low transverse accelerations A77-11427 PASSEIGEB AIBCBAFT Transportation in commercial aircraft of passengers having contagious diseases A77-10067 PJTHOGE8ESIS norpbological effects in rats after a 22-day space flight A77-11433 PATHOLOGICAL EFFECTS Pulmonary gas exchange in acute mountain sickness A77-10052 Pathophysiology of long-term hypoxinesia A77-11368 Antitissular antibodies and complement in hypokinesia A77-11402 On the expert diagnostic value of physiological parameters for objective monitoring of a pilot's condition in flight A77-11404 Pathomorphological changes in rat organs in the case of chronic inhalation of a polyethylsiloxane fluid A77-11460 PEBIPHEBAL CIBCOIATIOH Changes in central and peripheral hemodynamics, using prolonged antiorthostatic hypokinesia to simulate weightlessness A77-11457 PH FACTOB Light-induced membrane potential and pH gradient in Halobactenum halobium envelope vesicles A77-10703 PBABHACOLOGT Prevention of experimental motion sickness by scopolamine absorbed through the skin A77-10064 Drug effects on heart rate and heart rate variability during a prolonged reaction task A77-10274 Radioprotective effect of mexamin and cystamin on animals exposed to hypokinesia and ionizing radiation A77-11366 PHILOSOPHY On the possible uniqueness of intelligent life in the universe [8ASA-TT-F-17247] 1177-10799 PHOBIA Objective and automated measurement of dynamic vision functions A77-10148 PHOTOBECEPTOBS Photoreceptor membrane carbohydrate on the intradiscal surface of retinal rod disks A77-11476 PHOTOSBBSITIVITY Light-induced membrane potential and pB gradient in Balobacterinm halobium envelope vesicles A77-10703 Light-induced glutamate transport in Halobacteriu» halobina envelope vesicles. II - Evidence that the driving force is a light-dependent sodium gradient A77-1070U Functional interdependence of the visual and auditory analyzers during extremal stimulation A77-11362 PHOTOSIiTHESIS Investigation of the physiological activity of Chlorella vulgaris following an exposure to space flight factors aboard the Salyut orbital station A77-11355 Hodel of an ecological system closed relative to gas exchange with a periodically operating autotrophic unit. II - Stability of periodic cycles A77-11357 PHYSICAL EIBBCISE Neasurement of change in plasma volume during heat exposure and exercise A77-10053 Medical experiment H-171 - Besults from the second aanned Skylab mission A77-10056 Exercise in an hypoxic environment as a screening test for ischaemic heart disease A77-10068 Anaerobic threshold and maximal aerobic power for three modes of exercise A77-11099 Working capacity of man during stay at high altitudes A77-11364 State of the human motor system during exposure for many days to a nitrogen-oxygen environment at pressures of up to 5 atm A77-11409 Cardiorespiratory responses of cosmonauts to graded physical work after 30- and 63-day flights aboard the orbital base Salyut-4 A77-11452 PHYSICAL PITHESS Besponses of external respiration to +8 Gx overload for different training level of testees A77-11465 PHYSIOLOGICAL ACCELEBiTIOH Effect of hypovolemia, infusion, and oral rehydration on gradual onset *6z acceleration tolerance CIAF PAPBB 76-039] A77-10888 Effect of transverse accelerations on the motor function of the stomach A77-11376 PHYSIOLOGICAL EFFECTS Preliminary results of morphological and cytochemical studies on animals after a stay of 22 days in space flight aboard the Cosmos 605 satellite A77-10651 The effects of hyperoxia and hypokinesia on the formation and excretion of gaseous metabolites among rats A77-11381 Possibility of prolonged stay in water by means of a 'dry1 immersion method A77-11401 State of the human motor system during exposure for many days to a nitrogen-oxygen environment at pressures of up to 5 atm A77-11409 Dependence of human body weight loss on space flight duration A77-11415 Functional state of the liver-pancreas system during exposure to low transverse accelerations A77-11427 PHYSIOLOGICAL BESPOHSES Besponses of the autonomic nervous system during acclimatization to high altitude in man A77-10060 Effects of rapid round trips against time displacement on adrenal cortical-medullary circadian rhythms A77-10065 Cerebellar pressor response in the dog A77-11100 characteristics of the morphological responses of the viscera and endocrine glands of dogs subjected to gamma irradiation for 6 years A77-11378 Changes in the monosynaptic H-response of man during altitude decompression A77-11407 1-19 PHYSIOLOGICAL TESTS SUBJECT IHDEX A mathematical model of the human temperature regulatory system - Transient cold exposure response A77-12244 Study of metabolic response variation to an acoustic aggression metabolic recuperation after sonic boom N wave exposure [ISL-K-120/75] B77-11641 Cardiovascular, renal and respiratory effects of high intensity, intermediate duration, low frequency vibration [AD-A025Q98] N77-1166K PHYSIOLOGICAL TESTS Exercise in an hypoxic environment as a screening test for ischaemic heart disease A77-10068 The Soyuz-Apollo experimental flight - Preliminary results of medico-biological research carried out during flight of Soyuz-19 A77-11369 The effect of centrifugal force on the neck nystagmus of pigeons A77-11373 Adrenal function in man during exposure to a hyperbaric environment for many days /N2-O2, 5 atm/ A77-11410 Recovery of muscular functions in rats after prolonged hypokinesia A77-11412 Hemopoietic organs of mice during hypokinesis A77-11413 Aspects of optimizing rotation tests in electronystagmography A77-11456 Responses of external respiration to +8 Gx overload for different training level of testees A77-111I65 PHYSIOLOGY Principles of biodynamics. Volume 3: Physiological mechanisms in the mammal underlying posture, locomotion, and orientation in space [AD-A023691] H77-11661 PILOT PEBFOBHAHCE Readability of approach charts as a function of visual acuity, luminance, and printing format A77-10051 Study of in-flight working capability of pilots during simulated motion sickness A77-11392 Some principles for the recovery of central vision after temporary blindness A77-11411 Methods for studying the tolerance of pilots to inflight acceleration A77-11417 Evaluation of the state of the cardiovascular systems of helicopter flightcrews A77-11421 Tolerance to +Gz acceleration of pilots with a tendency tovard hypotensive responses under hot climate conditions A77-11435 Hegglin's syndrome in flight personnel vith atherosclerotic coronary cardiosclerosis and its clinical evaluation A77-11i(it5 Medical screening of flight personnel in certain types of chronic diseases of the myocardium A77-11461 Experiment design for pilot identification in compensatory tracking tasks N77-10380 Pilot workload and fatigue: A critical survey of concepts and assessment techniques [HASA-TH-D-8365] H77-11674 Influence of pilot incapacitation on lov speed and hovering flight [AD-A023728] N77-11684 PILOT SELECTION Evaluation of the rate of acoustic reception of radiotelegraph signals in psychological selection of candidates for pilot training A77-11394 PILOT TBAIBIHS Evaluation of the rate of acoustic reception of radiotelegraph signals in psychological selection of candidates for pilot training A77-11394 Effect of psychophysiological self-adjustment on flight training A77-11447 Enhancement of human effectiveness in system design, training, and operation: July 1974 - June 1975 [AD-A023941] H77-11687 PILOTS (PEBSOSBEL) Utilization of human centrifuge for training military pilots in the execution of protective straining maneuvers H77-11651 PITUITARY HOHHOHES Studies on the nature of plasma growth hormone A77-10700 PLiHTS (BOTiNT) Control of mineral nutrition of higher plants in biological life support systems A77-11356 Investigation of the biological effect of vibration on plants A77-11443 PLATELETS Interfacial biophysics of materials in contact with blood [PB-253117/6] N77-10787 PNEOHOGRAPHI Results of an impedance pneumography study A77-11400 POLLUTION MONITOBING Analytical notes - Electrochemical method for early detection and monitoring of coliforms A77-10988 Design, development, fabrication and testing of a portable self-contained respirable dust mass monitor [PB-251503/6] B77-11681 POLIHEES Biolized latex polyurethanes [PB-253085/5] H77-10786 POLYDBETHAHB BESIHS Biolized latex polyuretbanes [PB-253085/5] H77-10786 PORTABLE EQBIPHBHT A portable filter anomaloscope for color vision examination A77-101U9 POSITION (LOCATION) The assessment of position of stationary targets perceived during saccadic eye movement A77-10224 POSTFLIGBT ANALYSIS Morphological effects in rats after a 22-day space flight A77-11433 POTABLE IATEB Conditioning of water regenerated from water-containing wastes during space flight A77-11390 Search for a urine preservative as related to the oxidative-catalytic method of water regeneration A77-111114 ASTP chemical and microbiological analysis of potable water [NASA-TH-X-58192] H77-11675 POTASSIDM An attempt to disrupt the diurnal periodicity of the excretion of potassium in the urine A77-11383 PRECONDITIONING Influence of a precursor noise on the global action potential consecutive to an impulse noise in the Guinea pig [ISL-R-115/75] N77-11640 PBEDICTIOH ANALYSIS TECHNIQUES Theoretical aspects of the problem of predicting the state of the human organism during space flight A77-11«53 PRESERVATIVES Search for a urine preservative as related to the oxidative-catalytic method of water regeneration A77-11U1« 1-20 SUBJECT IHDEI RADIATIOI PEOTECTIOI Storage stability and laprovement of intermediate moisture foods, phase 3 [HASA-CB-15100U] H77-10792 PBODBCT DB7ELOPBEBT The development of chronic insertable oxygen electrodes [AD-A024633] H77-11657 PBOJECT HABAGEBEBT Continuing research in the development of interactive Dan-computer systeas for engineering-construction projects [PB-252927/9] H77-11679 PBOBB POSITIOB Effect of body position relative to the gravity vector on water balance A77-11411 PBOPHYLAXIS Prevention of decompression sickness as related to repeated extravehicular activities A77-11408 PROSTHETIC DEVICES Interfacial biophysics of materials in contact with blood [PB-253117/6] B77-10787 PROTECTIVE CLOIBIBG Calorimetry of the human body in a hermetic enclosure A77-114K2 PBOIEIB BETABOLISH Effect of accelerations, additional weight stress, and hypokinesia on protein metaoolism in the Japanese guail /Coturnix coturnix japonica/. I - Effect on muscle composition A77-11353 Some characteristics of the metabolism of proteins and riBonucleic acids in the central nervous system of rats in space flight aboard the Cosmos 605 satellite A77-11432 Effect of a 22-day space flight on the metabolism of skeletal muscle tissue in rats A77-11131 Diagnostic significance of free ammo acid content in the blood plasma during dietary protein deficiency in man A77-114I41 Protein fractions and their enzyme activity in the rat myocardium after a 22-day space flight A77-1145U PROTEIBS Effect of hydrocortisone and adrenocorticotropin on the conformational state of proteins in the brain and muscles A77-10661 Interfacial biophysics of materials in contact with blood [PB-253117/6] N77-10787 PSYCHOACOOSTICS Simultaneous three-channel signal detection - Performance and criterion as a function of order of report auditory perception tasks A77-11166 Evaluation of the rate of acoustic reception of radiotelegraph signals in psychological selection of candidates for pilot training A77-1139U Beyond averaging - The use of discriminant functions to recognize event related potentials elicited by single auditory stimuli A77-117U9 PSYCHOLOGICAL EFFECTS Effects of psychosocial stimuli on plasma renin activity in rats A77-10799 PSYCHOLOGICAL TESTS Psychologic and psychophysiologic response to 105 days of social isolation A77-10063 psrcsoaoToa PEBFOBBABCE Psychomotor test performance and sleep patterns of aircrew flying transmeridional routes A77-10600 S2 probability and CNV (Contingent Negative Variation) signal detection task and selective reaction time task [IZF-1975-11] N77-11668 PSICHOPHYSIOL06Y Psychologic and psychophysiologic response to 105 days of social isolation \ A77-10063 Cognitive activity of can during adaptation to short-tera weightlessness \ A77-11360 Functional interdependence of the visual and auditory analyzers during extremal stimulation A77-11362 Effect of psychophysiological self-adjustment on flight training A77-11U47 PUBLIC HEALTH Transportation in commercial aircraft of passengers having contagions diseases A77-10067 POLBOBABY CIECOLATIOB Cyclic hypoxic pulmonary vasoconstriction induced by concomitant carbon dioxide changes A77-11098 Pulmonary hypertension Book A77-12425 PDLBOBABY FOBCTIOSS Pulmonary gas exchange in acute mountain sickness A77-10052 Cardiovascular and pulmonary dynamics by guantitative imaging A77-10709 Method of calculating the excess pressure in human lungs resulting from cabin decompression A77-11459 QUALITY COBTBOL Evaluation and application of the guantitative indices of the guality of operator work in spacecraft control A77-11418 Storage stability and improvement of intermediate moisture foods, phase 3 [NASA-CE-151004] N77-10792 QOiHTOH HECBABICS Electrospectroscopic method for evaluating the interaction of radiation with DMA molecules A77-11385 BADAB BEAHS Impact of radar irradiation on human systems A77-10250 BADIATIOB DABAGE Effect of penetrating radiation on skeletal muscles of rats in weightlessness A77-10061 BADIATIOB DOSAGE Average latitudinal variation in ultraviolet radiation at the earth's surface biological sensitivity and dosage A77-10991 The effect of the chronic action of small dosages of ionizing radiation on the excretion of gaseous metabolites among white rats A77-11379 BADIATION EFFECTS Impact of radar irradiation on human systems A77-10250 First results of an investigation of the effects of microwave radiation with low power density on the behavior of rats [HBL-1974-15] N77-10778 Experiments aooard biosatellites Kosmos-690 and Kosmos-782 biological effect of solar and galactic radiation [NASA-TT-F-17215] H77-10782 The effect of 1.6 GHz radiation on neurotransmitters in discrete areas of the rat brain [AD-A023677] N77-11662 BADIATIOB PROTECTION Radioprotective effect of mexamin and cystamin on animals exposed to hypokinesia and ionizing radiation A77-11366 1-21 BADIATIOH SBIBLDIIG SOBJBCI IIDEI BADIAIIOI SHIELDIH6 Calculating relaxation length from measurement data on biological shielding materials for nuclear reactors A77-11309 BADIATIOH SICKBESS Direct simulation of a radiobiological survival experiment A77-11426 BADIO IBLBGBAPBY Evaluation of the rate of acoustic reception of radiotelegraph signals in psychological selection of candidates for pilot training A77-1139U BADIOBIOLOGY Characteristics of the morphological responses of the viscera and endocrine glands of dogs subjected to gamma irradiation for 6 years A77-11378 The effect of the chronic action of small dosages of ionizing radiation on the excretion of gaseous metabolites among white rats A77-11379 Electrospectroscopic method for evaluating the interaction of radiation Kith DHA molecules A77-11385 Coronary vessels of the rabbit following single irradiation of the heart area with a dose of 2400 rad A77-11120 Effect of alpha radiation on Chlocella vulgaris at different stages of cellular cycle A77-11U22 A system of remote utilization of a computer during the processing of biological data A77-12379 Experiments aboard biosatellites Kosmos-690 and Kosmos-782 biological effect of solar and galactic radiation [HASA-TT-F-17215] N77-10782 BAOIOFATBOLOGI Impact of radar irradiation on human systems A77-10250 Direct simulation of a radiobiological survival experiment A77-11426 BATS First results of an investigation of the effects of microwave radiation with low power density on the behavior of rats [MBL-1974-15] K77-10778 The contraction prolonging action of 9-anthroic acid (AHCA) on the isolated rat diaphragm and the effects of soman on this phenomenon [HBL-1975-25] N77-10779 The function of the gastrointestinal channel of the rat during shock [HBL-1975-16] N77-10785 The effect of 1.6 GHz radiation on neurotransmitters in discrete areas of the rat brain [AD-A023677] 877-11662 BECEPIOBS (PHYSIOLOGY) Receptor contributions to steady-state sensitivity in the peripheral retina of human observers H77-1165U REFLEXES Cerebellar pressor response in the dog A77-11100 State of the labyrinth tonic reflexes of position during the administration of trace elements to rabbits /copper* manganese* and cobalt/ A77-11375 BEGEHEBATIOH (ENGIBEEBIBG) A sorption method for the reclamation of water for the personal hygiene of cosmonauts A77-11382 Conditioning of water regenerated fron water-containing wastes during space flight A77-11390 Search for a urine preservative as related to the oxidative-catalytic method of water regeneration A77-11444 BEGBHBBATIOH (PHYSIOLOGY) Response of the fibroblasts of granulation tissue in regenerating skin to chronical hypoxia A77-11397 BBGBBSSIOB AHALYSIS Bidge and Bayes identification for the quasllinear human controller in compensatory tracking A77-10123 BBBOTB COBSOLBS A system of remote utilization of a computer during the processing of biological data A77-12379 BBHOIB COHIBOL Shuttle manipulator design reviewed A77-11899 Distribution of control decisions in remote manipulation A77-12427 BBBAL POBCTIOH Effect of a strong constant magnetic field and a hypomagnetic environment on the histochemical indices of the liver in white rats A77-11354 Effect of nerobol on the fluid-electrolyte metabolisn and function of kidneys in man during 120-day hypokinesia A77-11440 BBPaODOCTIOS (BIOLOGY) Effect of the 22-day space flight factors on the state of sex glands and reproductive function of rats A77-11455 BBPBODOCTIVE SYSIEBS Hypokinesia and macroscopic changes in seminal vesicles A77-11367 BESPIBATOBS Procedure for continuous-flow respirator flovrate determination [PB-252694/5] H77-10797 Procedure for testing strength of hose and couplings [PB-252696/0] 1177-10798 HESPIBATOBY DISEASES Relations of the hydroxyproline concentration in the lungs to the lung weight* the silica and aluminum concentrations* and the dust dose* after repeated intratracheal coal dust application in a long-term test with rats A77-12288 BESPIBATOBI IHPBDAHCE Results of an impedance pneumography study A77-11400 RESPIRATORY PHYSIOLOGY Anaerobic threshold and maximal aerobic power for three modes of exercise A77-11099 Influence of hyperoxia on the characteristics of external respiration* cardiovascular system, and gas composition of blood A77-11393 Effect of systematic gravity exposures on external respiration during prolonged immersion A77-11437 Cardiorespiratory responses of cosmonauts to graded physical work after 30- and 63-day flights aboard the orbital base Salyut-4 A77-11452 Periods of retainment of increased general resistance of the organism under different conditions of adaptation to oxygen deficiency A77-11458 Pathomorphological changes in rat organs in the case of chronic inhalation of a polyethylsiloxane fluid A77-11460 Responses of external respiration to +8 Gx overload for different training level of testees A77-11U65 Intracellular buffering of heart and skeletal muscles during the onset of hypercapnia A77-11892 BESPIBA10BI BATE The effect of different regimes of motor activity on the adaptation of man to high altitude A77-11371 Results of an impedance pneumography study A77-11400 BESPIBATOBY SYSTEH Pulmonary hypertension Book A77-12425 1-22 SUBJECT IBDEI SOIL SCIEBCE RESPONSES The effect of pre-adapting spectral stimuli on visual response CAD-A024312] H77-11659 BETICDLOCITBS Development of reticulocytosis in the peripheral blood during exposure to a constant magnetic field A77-11380 BETIHi Photoreceptor membrane carbohydrate on the intradiscal surface of retinal rod disks A77-11476 Receptor contributions to steady-state sensitivity in the peripheral retina of human observers N77-11654 BETIBAL IHAGES Rivalrous texture stereograms binocular fusion explained by spatial-frequency-tuned channels A77-11999 BHEOLOGJ Cardiovascular, renal and respiratory effects of high intensity, intermediate duration, low frequency vibration [AD-A025098] H77-11664 BIBOHOCLEIC ACIDS Some characteristics of the metabolism of proteins and ribonucleic acids in the central nervous system of rats in space flight aboard the Cosmos 60S satellite A77-11432 BIDIHG QUALITY Subjective response to combined noise and vibration during flight of a large twin-jet airplane [NASA-TH-X-3406] N77-10790 An experimental study for determining human discomfort response to roll vibration [NASA-TN-D-8266] N77-11666 User evaluation of ride technology research [NASA-CE-2746] M77-11667 BOBOTS Control and trajectory optimization of a robot arm [AD-A023669] N77-11688 BOLL An experimental study for determining human discomfort response to roll vibration [HASA-TH-D-8266] H77-11666 ROTATING ENVIEONHENTS Aspects of optimizing rotation tests in electronystagmography A77-11456 Effect of blood redistribution in the human organism on the perception of body position in space A77-11464 BOBI LASEBS Reduction of target detectability by laser protective materials [AD-A024383] B77-11682 SACCAOIC EYE BOVEHE8TS The assessment of position of stationary targets perceived during saccadic eye movement A77-1022U SAPETI FACTORS Safe use of the P-3 strobe lamp [AD-A02I4036] B77-11658 SALIDT SPACE STATIOH Preliminary results of medical studies during the flight of the second expedition of the Salyut 4 orbital station A77-11450 Orthostatic tolerance of cosnonauts after 30- and 63-day flights onboard the orbital base Salyut-4 A77-11451 Cardiorespiratory responses of cosmonauts to graded physical work after 30- and 63-day flights aboard the orbital base Salyut-U A77-11152 Second expedition of the Salyut-4 orbital station. Certain results and tasks of medical research [BASA-TT-F-17223J H77-10783 SABITATIOB Food sanitation and air safety A77-10066 A sorption method for the reclamation of water for the personal hygiene of cosmonauts A77-11382 SEATS Psycho-physiological and physio-chemical assessment of acceleration induced changes in humans positioned in various seatback angle configurations H77-11647 Centrifuge assessment of a reclining seat H77-11648 SEDATIVES Drug effects on heart rate and heart rate variability during a prolonged reaction task A77-10274 SEHICIBCOLAB CABALS Current trends in biophysical studies of the vestibular function A77-11386 SEBSOBIUOTOB PERFORHiBCE Objective and automated measurement of dynamic vision functions A77-10148 Effect of positive longitudinal acceleration on the transmission properties of a human operator A77-11359 Dynamics of the motor components of the optokinetic nystagmus during exposure of the vestibular apparatus to angular accelerations A77-11374 Evaluation of the rate of acoustic reception of radiotelegraph signals in psychological selection of candidates for pilot training A77-11394 SHIPS An evaluation of a fuel-soluble organoboron biocide for control of sulfate-reducing bacteria in shipboard fuel tanks [AD-A024017] N77-11643 SHOCK The function of the gastrointestinal channel of the rat during shock [BBL-1975-16] N77-10785 SIGBAL DETECTIOB 52 probability and CUV (Contingent Negative Variation) signal detection task and selective reaction time task [IZF-1975-11] 1177-11668 SIGBAL TO BOISE BATIOS Results of an impedance pneumography study A77-11400 SILOXAHES Pathomorphological changes in rat organs in the case of chronic inualation of a polyethylsiloxane fluid A77-11460 SKIB (AHATOHI) Response of the fibroblasts of granulation tissue in regenerating skin to chronical hypoxia A77-11397 SKIS TEHPEEATDRE (BIOLOGY) Thermistor holder for skin temperature measurements [ HASA-CASE-ABC-10855-1J S77-10780 SKYLAB PEOGHAH Bioprocessing in space [HASA-TB-X-74157] B77-10777 SKYLAB 3 Nedical experiment M-171 - Besults from the second manned Skylao mission A77-10056 SLEEP Cardiac output during human sleep A77-10054 Central nervous regulation of body temperature during sleep A77-10113 Psychomotor test performance and sleep patterns of aircrew flying transnendional routes A77-10600 Activity of nenronal populations of human subcortical structures during sleep A77-11750 SOCIAL ISOLATION Psychologic and psychophysiologic response to 105 days of social isolation A77-10063 SOIL SCIBBCE The puzzle of the Bartian soil A77-11480 1-23 SOLAB COSBIC BAIS SUBJECT INDEX SOLAS COSBIC BATS Experiments aboard biosatellites Kosnos-690 and Kosmos-782 biological effect of solar and galactic radiation [NASA-TT-F-17215] tm-10782 SOLAB RADIATIOH Average latitudinal variation in ultraviolet radiation at the earth's surface biological sensitivity and dosage A77-10991 SOLID HASTES Physicochemical purification of the gas-vapor phase formed during dessication of solid waste from human vital activity A77-11U19 SOHIC BOOBS Study of metabolic response variation to an acoustic aggression metabolic recuperation after sonic noon N wave exposure [ISL-R-120/75] N77-11641 SODHD GEHEBATOBS Study of metabolic response variation to an acoustic aggression metabolic recuperation after sonic boom N wave exposure [ISL-R-120/75] N77-11611 SODHD PBESSDSE Influence of the peak pressure and duration of impulse noise (gun fire) on the hearing of the guinea pig [ISL-B-109/75] N77-11639 SOYOZ SPACECRAFT State of vascular regulation and regional hemodynamics in Soyuz-12 and Soyuz-13 crewmembers before and after flight A77-11388 SPACE EHVIRONMEHT SIBDLATIOH Changes in central and peripheral hemodynamics, using prolonged antiorthostatic hypokinesia to simulate weightlessness A77-11457 SPACE FLIGHT FEEDIHG Determination of the adhesion properties of foodstuffs A77-1138IJ SPACE FLIGHT STRESS Medical experiment H-171 - Results from the second manned Skylab mission A77-10056 Free ammo acids in human blood plasma during space flights A77-10057 Effects of head-down tilt on fluid and electrolyte balance A77-10058 Effect of penetrating radiation on skeletal muscles of rats in weightlessness A77-10061 Antiorthostatic hypokinesia as a method of weightlessness simulation A77-10062 Preliminary results of morphological and cytochemical studies on animals after a stay of 22 days in space flight aboard the Cosmos 605 satellite A77-10651 Investigation of the physiological activity of Chlorella vulgaris following an exposure to space flight factors aboard the Salyut orbital station A77-11355 Cognitive activity of man during adaptation to short-term weightlessness A77-11360 Pathopbysiology of long-term hypokinesia A77-11368 The Soyuz-Apollo experimental flight - Preliminary results of medico-biological research carried out during flight of Soyuz-19 A77-11369 An attempt to disrupt the diurnal periodicity of the excretion of potassium in the urine A77-11383 State of osseous tissue under conditions of hypokinesia and weightlessness, and the effect of tbyrocalcitonin A77-11387 State of vascular regulation and regional hemodynamics in Soyuz-12 and Soyuz-13 crewmembers before and after flight A77-11388 Results of exposure of mammalian cell cultures aboard an earth satellite A77-11395 The effect of a long-time influence of a constant and alternating 1000-oersted magnetic field on mitotic activity A77-11396 Antitissular antibodies and complement in hypokinesia A77-11102 Change lu state characteristics of the parasympatnetic nervous system during hypokinesia in rabbits A77-11103 Rat experiment on a 22-day flight on the Diosatellite Cosmos 605 /Objectives and methods/ A77-11105 Activity of DMA depolymetases in the rat spleen after flight aboard the Cosmos 605 satellite A77-11K06 Recovery of muscular functions in rats after prolonged hypokinest.a A77-11112 Hemopoietic organs of mice during hypokinesis A77-11U13 Dependence of human body weight loss on space flight duration A77-11115 Effect of alpha radiation on Chlorella vulgaris at different stages of cellular cycle A77-11U22 Some characteristics of the metabolism of proteins and ribonucleic acids in the central nervous system of rats in space flight aboard the Cosmos 605 satellite A77-11K32 Morphological effects in rats after a 22-day space flight A77-11U33 Effect of a 22-day space flight on the metabolism of skeletal muscle tissue in rats A77-1143I4 Some responses of man to prolonged centripetal accelerations /+Gz/ of small values A77-11U36 Effect of systematic gravity exposures on external respiration during prolonged immersion A77-11«37 Human cardiovascular responses to orthostatic tests after highland adaptation A77-111138 Quantitative evaluation of ultrastructural changes in the myocardium of the rat during prolonged hypokinesia A77-11439 Effect of nerobol on the fluid-electrolyte metabolism and function of kidneys in man during 120-day hypokinesia A77-114UO Diagnostic significance of free ammo acid content in the blood plasma during dietary protein deficiency in man A77-11141 Combined effect of hypokinesis and elevated oxygen content on animal resistance to carbon monoxide A77-11U«6 Preliminary results of medical studies during the flight of the second expedition of the Salyut "4 orbital station A77-11U50 Orthostatic tolerance of cosmonauts after 30- and 63-day flights onboard the orbital base Salyut-t A77-11U51 Cardiorespiratory responses of cosmonauts to graded physical work after 30- and 63-day flights aboard the orbital base Salyut-4 A77-11452 Theoretical aspects of the problem of predicting the state of the human organism during space flight A77-11453 Protein fractions and their enzyme activity in the rat myocardium after a 22-day space flight A77-11454 SUBJECT IIDEX STBESS (PHYSIOLOGY) Effect of the 22-day space flight factors on the state of sex glands and reproductive function of rats A77-11155 Quantitative histochemical determination of creatine kinase activity in nanogran amounts of rat nyocardium A77-11462 Effect of orotic acid on weight dynamics in rats subjected to restrained motor activity A77-11463 Effect of blood redistribution in the human organisn on the perception of body position in space A77-11161 Responses of external respiration to +8 Gx overload for different training level of testees A77-11165 Genesis of vestibnlo-vegetative disorders under weightlessness conditions A77-11166 Second expedition of the Salyut-1 orbital station. Certain results and tasks of medical research [HASA-TT-F-17223] H77-10783 SPACE PEBCEPTIOH Effect of blood redistribution in the human organism on the perception of body position in space A77-11161 Bivalrous texture stereograms binocular fusion explained by spatial-frequency-tuned channels A77-11999 SPACE PBOCESSIHG Bioprocessing in space [HASi-TH-X-71157] N77-10777 SPACE BATIOHS A Space Shuttle galley system [IAF PAPEB 76-011] A77-10889 SPACE SBUTTLE OEBIIBBS Shuttle crew training revision needed A77-11516 SPACE SHUTTLES A Space Shuttle galley system [liF PAPEB 76-011] A77-10889 Shuttle manipulator design reviewed A77-11899 Bioprocessing in space [NASA-TH-I-71157] N77-10777 Crew training and support activities [GPO-75-981] N77-11678 SPACE STATIOBS Eye movements occurring during head turns aboard artificial gravity stations A77-11351 SPACE SOUS Calorimetry of the human body in a hermetic enclosure A77-11112 Development and fabrication of an advanced liquid cooling garment [SASA-CB-137971] N77-11673 SPACECBAFT CABIB ATMOSPHERES Possible ways of solving the problem of 'biological compatibility' of crew members in long term space flights A77-11389 Effect of cupric bromide on the intensity of release of gaseous substances from a waste disinfection facility A77-11121 Physicochemical purification of the gas-vapor phase formed during dessication of solid waste from human vital activity A77-11119 Evaluation of a spacecraft nitrogen generator [SASA-C8-137930] H77-11672 SPACECBAFT COHTAHINATIOI Investigation of the composition of volatile compounds in sweat and urine in man A77-11365 Possible ways of solving the problem of 'biological compatibility1 of crew members in long term space flights A77-11389 Effect of cupric bromide on the intensity of release of gaseous substances from a waste disinfection facility A77-11121 SPACBCBAFT COIIBOL Evaluation and application of the quantitative indices of the quality of operator vork in spacecraft control A77-11118 SPACECBAFT DBSIGB Shuttle manipulator design reviewed 477-11899 SPACECBEiS State of vascular regulation and regional hemodyuamics in Soyuz-12 and Soyuz-13 crewmembers before and after flight A77-11388 Possible ways of solving the problem of 'biological compatibility1 of crew members in long term space flights A77-11389 Shuttle crew training revision needed A77-11516 Crew training and support activities [GPO-75-981] H77-11678 SPACELAB The possibilities of Spacelab for solving medical problems A77-11589 SPATIAL FILTBBIHG Bivalrous texture stereograms binocular fusion explained by spatial-freguency-tuned channels A77-11999 SPBCTBOSCOPIC AHALYSIS Electrospectroscopic method for evaluating the interaction of radiation with DBA molecules A77-11385 SPEECH BECOGHITIOH Identification of vowels excerpted from /!/ and /r/ contexts A77-10138 Separation of speech from interfering speech by means of harmonic selection 477-10139 SPLEEB Activity of DBA depolymerases in the rat spleen after flight aboard the Cosmos 605 satellite A77-11106 SPOBES Joint inflight biomedical experiments performed during the ASTP spaceflight bacteriological experiments [IAF PAPEH 76-031] A77-10887 STEBBOCHEHISTBY Monocarboxylic acids from oxidation of acyclic isoprenoid alkanes by Hycobacterium fortuitum A77-10705 STEBEOSCOPIC VISIOH Bivalrous texture stereograms binocular fusion explained by spatial-frequency-tuned channels A77-11999 STEBOIDS Effect of nerobol on the fluid-electrolyte metabolism and function of kidneys in man during 120-day hypokinesia A77-11110 STIHOLAIT Drug effects on heart rate and heart rate variability during a prolonged reaction task A77-10271 STOHACB Effect of transverse accelerations on the motor function of the stomach A77-11376 STOBAGE STABILITY Storage stability and improvement of intermediate moisture foods, phase 3 [NASA-CB-151001] H77-10792 STOBAGE (OBBOABD BO.UIPHEBT) A Space Shuttle galley system [IAF PAPEB 76-011] A77-10889 STBBPTOSTCBTBS Joint inflight biomedical experiments performed during the ASTP spaceflight bacteriological experiments [IAF PAPEB 76-031] A77-10887 STBESS (BIOLOGY) Cellular and molecular aspects of adaptation A77-11130 STBBSS (PHYSIOLOGY) Pulmonary gas exchange in acute mountain sickness A77-10052 1-21 StBBSS (PSYCHOLOGY) SUBJECT IHDEI Plasma angiotensin II levels in hypoxic and hypovolenic stress in unanesthetized rabbits A77-11097 STBBSS (PSYCHOLOGY) Psychologic and psychophy-siologic response to 105 days of social isolation 177-10063 STBBSS COBCEHTBATIOH Utilization of hanao centrifuge foe training military pilots in the execution of protective straining maneuvers 1177-11651 STHOBOSCOPES Safe use of the P-3 strobe lamp [AD-A02U036] H77-11658 SOBBBBGIHG Possibility of prolonged stay in water by means of a 'dry' immersion method A77-11U01 Effect of systematic gravity exposures on external respiration daring prolonged immersion A77-11437 S06ABS The diurnal variation of neutral hepatic fructose 1,6-diphosphatase in partially inbred populations of rats and in outbred populations of Hicrotus montanus A77-10990 SDLFAIES An evaluation of a fuel-soluble organoboron biocide for control of sulfate-reducing bacteria in shipboard fuel tanks -[AD-A021017] N77-11613 SOPIHB POSITIOH Effect of body position relative to the gravity vector on water balance A77-11411 SDBVIVAL Direct simulation of a radiobiological survival experiment A77-11U26 SWEAT Investigation of the composition of volatile compounds in sweat and urine in man A77-11365 S1IHB Ventricular pathology in swine at high sustained *G sub z H77-116U6 Effect of sustained +G sub z acceleration on cardiac output and fractionation of cardiac output in awake miniature swine N77-11650 SYMPATHETIC HEEVOOS SISTEB Effects of psychosocial stimuli on plasma renin activity in rats A77-10799 Change in state characteristics of the parasympathetic nervous system during hypokinesia in rabbits A77-11I403 SIHCHBOHISH Analysis of the problem of synchronizing the operation of different devices during the conversion and storage of digital electrocardiogram data A77-12381 TABLES (DATA) Average latitudinal variation in ultraviolet radiation at the earth's surface biological sensitivity and dosage A77-10991 TABSBT ACQDISITIOH Computerized analysis of eye movements during static display visual search [AD-A02U100] N77-11680 Target detection in rapidly-changing visual seguences[AD-A023781] N77-11685 TABGET HECOGHITIOH Reduction of target detectability by laser protective materials [AD-A024383] N77-11682 TEETH Theory of orthodontic motions S77-10211 IEBPEBATB BEGIOIS The time of adaptation of flying personnel to subtropical climates A77-11377 TEITDBES Bivalrous texture stereograms binocular fusion explained by spatial-freguency-tuned channels A77-11999 THBBBAL PBOTBCTIOB Improved thermal protection and rewarm procedures for cold water divers [AD-A024213] H77-11660 THBBBISTOBS Thermistor holder for skin temperature measurements [HASA-CASE-ABC-10855-1] B77-10780 THBBHOBEGOLATIOH Central nervous regulation of body temperature during sleep A77-10113 A model of the physiological thermoregulation system A77-11391 Calonnetry of the human body in a hermetic enclosure A77-11442 A mathematical model of the human temperature regulatory system - Transient cold exposure response A77-12244 THBESHOLDS (PBBCBPTIOH) Influence of auditory fatigue on masked pure-tone thresholds A77-10137 TIBB DEPEHDEHCE Duration of whole-body vibration exposure - Its effect on comfort A77-10341 TISSDBS (BIOLOGY) Impact of radar irradiation on human systems A77-10250 Study of phosphatase activity in the bone tissue and blood serum during 90-day hypokinesia A77-11370 State of osseous tissue under conditions of hypokinesia and weightlessness, and the effect of thyrocalcitonin A77-11387 Potential biomedical applications of ion beam technology[NASA-Tn-X-73512] B77-11655 TOBSO The effect of the torso boundaries on the magnetocardiogram A77-11710 TOXIC HAZABDS Food sanitation and air safety A77-10066 Investigation of the composition of volatile compounds in sweat and urine in man A77-11365 Combined effect of hypokinesis and elevated oxygen content on animal resistance to carbon monoxide A77-11446 Pathomorphological changes in rat organs in the case of chronic inhalation of a polyethylsiloxane fluid A77-11160 TBACE ELEMENTS State of the labyrinth tonic reflexes of position during the administration of trace elements to rabbits /copper, manganese, and cobalt/ A77-11375 TBAFFIC COHTBOL Visibility of traffic control devices - Catering for the real observer A77-10273 TBAHSPOBT AIBCBAFT Subjective response to combined noise and vibration during flight of a large twin-Jet airplane [NASA-TH-X-3106] N77-10790 TBAHSPOBT PBOPBBTIES Light-induced glutamate transport in Halobacterium halobium envelope vesicles. II - Evidence that the driving force is a light-dependent sodium gradient A77-10704 Determination of oxygen tension by measurement of net charge transport A77-12245 1-26 SUBJECT ISDEI VISUAL STIBOLI TBAHSVBBSE ACCELBBATIOB Effect of transverse accelerations on the notor function of the stomach A77-11376 TBOPIC1L BEGIOBS The time of adaptation of flying personnel to subtropical cliaates 477-11377 O.S.S.B. Equipment for the cosmonaut tHiSA-TT-F-17275] N77-11670 DLTBASOBIC BADIATIOB Ultrasonic Doppler cardiograph; in the nedical control system A77-11399 OLTBAVIOLBT BADIATIOS Average latitudinal variation in ultraviolet radiation at the earth's surface biological sensitivity and dosage A77-10991 OHIVEBSE On the possible uniqueness of intelligent life in the universe [BASA-TT-F-172II7] H77-10799 OBIHALTSIS Investigation of the conposition of volatile compounds in sweat and urine in man A77-11365 OBIBB Search for a urine preservative as related to the oxidative-catalytic method of water regeneration A77-11U44 Electrolytic pretreatment unit gaseous effluent conditioning [HASA-CR-151101] H77-1167-1 VASOCOBSTBICT10B Cyclic hypozic pulmonary vasocoostriction induced by concomitant carbon dioxide changes A77-11098 VASODILATIOH Coronary vessels of the rabbit following single irradiation of the heart area with a dose of 2400 rad A77-11420 VBCTOBCABDIOGBAPHT Changes in clinical cardiologic measureaents associated with high «-G sub i stress H77-11645 VEStlBULAB BTSTAGHUS The effect of centrifugal force on the neck nystagmus of pigeons A77-11373 Dynamics of the motor components of the optokinetic nystagmus during exposure of the vestibular apparatus to angular accelerations A77-11374 Current trends in biophysical studies of the vestibular function A77-11386 Effect of caloric stimulation of the vestibular system on body temperature A77-11K23 Effect of psychotropic drugs on some indices of the vestibular function A77-11U28 VBSTIBOLAB TESTS Biophysical analysis of the action of Coriolis acceleration on the vestibular analyzer A77-10652 Eye movements occurring during head turns aboard artificial gravity stations A77-11351 Dynamics of the lotor components of the optokinetic nystagmus during exposure of the vestibular apparatus to angular accelerations A77-11374 Current trends in biophysical studies of the vestibnlar function A77-11386 Effect of caloric stimulation of the vestibnlar system on body temperature A77-11U23 Effect of psychotropic drugs on sone indices of the vestibular function A77-11U28 VESTIBULES Aspects of optimizing rotation tests in electronystagmography A77-11456 Genesis of vestibule-vegetative disorders under weightlessness conditions A77-11U66 VIBB&TIOH EFFECTS Noise and vibration ride comfort criteria [NASA-Tfl-X-73975] S77-10791 VIBBATIOR TESTS Subjective response to combined noise and vibration during flight of a large twin-jet airplane [ NASA-TH-X-3<106 ] B77-10790 TIBBATIOBAL STBBSS Duration of whole-body vibration exposure - Its effect on comfort A77-10341 Investigation of the biological effect of vibration on plants A77-11443 Cardiovascular, renal and respiratory effects of high intensity, intermediate duration, low frequency vibration [AD-A025098] H77-11664 VIKIRG HABS PBOGBAS The puzzle of the Martian soil A77-11480 life beyond the earth Viking biology experiments A77-11550 VIBOSES Virion aggregation and disinfection of water viruses by bromine [PB-253087/1] H77-11642 VISCEBA Characteristics of the morphological responses of the viscera and endocrine glands of dogs subjected to gamma irradiation for 6 years A77-11378 VISIBILITY Visibility of traffic control devices - Catering for the real observer 477-10273 VISIOH An application of Wiener analysis to human visual psychophysical response 1177-11669 VISUAL ACDITI Beadability of approach charts as a function of visual acuity, luminance, and printing format A77-10051 An automated miniaturized Haploscope for testing binocular visual function A77-10147 Visibility of traffic control devices - Catering for the real observer A77-10273 Soae principles for the recovery of central vision after temporary blindness A77-1141I! VISUAL FIELDS Target detection in rapidly-changing visual sequences CAD-A023781] B77-11685 VISUAL PEBCEPTIOB Objective and automated measurement of dynamic vision functions A77-10148 The assessment of position of stationary targets perceived during saccadlc eye movement A77-1022H Functional interdependence of the visual and auditory analyzers during extremal stimulation A77-11362 Seduction of target detectability by laser protective materials [AD-A021383] 1177-11682 Dynamic contrast requirements relationship between human visual system and displayed imagery [AD-A023973] B77-11683 VISUAL STIHULI Functional interdependence of the visual and auditory analyzers during extremal stimulation 477-11362 1-27 VISUAL TASKS SUBJECT IHDEX The effect of pre-adapting spectral stimuli on visual response [AD-A0214312] N77-11659 VISDAL TASKS Study of subjective evaluations of the normal state of operators in a long-term tracking procedure A77-11448 VOICE COHHDHICATION Identification of vowels excerpted from /!/ and /r/ contexts A77-10138 Separation of speech from interfering speech by means of harmonic selection A77-10139 VOiELS Identification of voxels excerpted from /!/ and /r/ contexts 477-10138 w HASTE DISPOSAL A Space shuttle galley system [IAF PAPER 76-OU14] A77-10889 Physicochemical purification of the gas-vapor phase formed during dessication of solid waste from human vital activity A77-1HI19 WASTE UTILIZATION Conditioning of water regenerated from water-containing wastes --- during space flight A77-11390 HATBB Aqueous artefacts: The riddle of bound water [AD-A0216t3] N77-11663 HATEB BALANCE Effect of body position relative to the gravity vector on water balance A77-11111 HATEB HANAGEHEHT A Space Shuttle galley system [IAP PAPER 76-Oltl] A77-10889 HATEB POLLUTION Analytical notes - Electrochemical method for early detection and monitoring of coliforms A77-10988 HATEB QUALITY A sorption method for the reclamation of water for the personal hygiene of cosmonauts A77-11382 Conditioning of water regenerated from water-containing wastes --- during space flight A77-11390 HATEB RECLAMATION A sorption method for the reclamation of water for the personal hygiene of cosmonauts A77-11382 Search for a urine preservative as related to the oxidative-catalytic method of water regeneration Development assessment of wash water reclamation [NASA-CE-13793 On the possible uniqueness of intelligent life in the universe [NASA-TT-F-17247] H77-10799 PERSONAL AUTH08 IHDEI TIGBAHIAH, B. A. SHPACHEHKO. D. I. Evaluation of the rate of acoustic reception of radiotelegraph signals in psychological selection of candidates for pilot training A77-1139U Effect of psychophysiological self-adjustment on flight training A77-11447 SBULZHEHKO. E. B. Possibility of prolonged stay in water by means of a 'dry1 immersion method A77-1 11(01 Effect of systematic gravity exposures on external respiration during prolonged immersion A77-11437 Responses of external respiration to +8 Gx overload for different training level of testees A77-11465 SHDSI, I. V. Effect of a strong constant magnetic field and a hypomagnetic environment on the histochemical indices of the liver in white rats A77-11354 SHVETS, ?. H. Antitissular antibodies and complement in hypokinesia A77-11402 Hemopoietic organs of mice during hypokinesis A77-11413 SIGAl, C. E. SAINT II documentation manual [AD-A020286] N77-11689 SIHONOV, E. E. Evaluation of the effect of impact accelerations on the organism from laboratory data A77-11352 SIHOHOV, V. H. Control of mineral nutrition of higher plants in biological life support systems A77-11356 SIIIAK. G. S. Physicochemical purification of the gas-vapor phase formed during dessication of solid waste from human vital activity A77-11449 SKOROGLIADOVi, H. P. Recovery of muscular functions in rats after prolonged hypokinesia A77-11412 SHIRNOV, K. V. Effect of transverse accelerations on the motor function of the stomach A77-11376 Functional state of the liver-pancreas system during exposure to low transverse accelerations A77-11427 SHOLSKII, L. P. Hypokinesia and macroscopic changes in seminal vesicles A77-11367 SHYDEB, H. Computerized analysis of eye movements during static display visual search [AD-A024100] N77-11680 SOKOLOT, B. L. Investigation of the composition of volatile compounds in sweat and urine in man A77-11365 SOBDAHL, L. A. Coronary flow and myocardial biochemical responses to high sustained +G sub z acceleration H77-11649 SOBKII, B. D. Simultaneous three-channel signal detection - Performance and criterion as a function of order of report A77-11166 SPITZA, I. I. The Soyuz-Apollo experimental flight - Preliminary results of medico-biological research carried out during flight of Soyuz-19 A77-11369 SQOIRES, K. C. Beyond averaging - The use of discriminant .functions to recognize event related potentials elicited by single auditory stimuli A77-11749 STA8ISLAVOVA, B. Effect of accelerations, additional weight stress, and hypokinesia on protein metabolism in the Japanese guail /Coturnn coturnix japonica/. I - Effect on muscle composition A77-11353 STEPAHOV. L. A. Comparative characterization of electrocardiograms in flight personnel with normal and excessive weight under moderate hypoxia A77-11416 STEPAHOVA, S. I. An attempt to disrupt the diurnal periodicity of the excretion of potassium in the urine A77-11383 STONE, B. L. Cerebellar pressor response in the dog A77-11100 Coronary flow and myocardial biochemical responses to high sustained +G sub z acceleration N77-11649 STRAUSS, A. H. Theory of orthodontic motions N77-10241 diodynamics of deformable human body motion 877-10260 STBDNK, B. L. The posterior aortic wall echocardiogram - Its relationship to left atrial volume change A77-11049 STBZBIZBOVSKII. A. D. The effect of a long-time influence of a constant and alternating 1000-oersted magi,3tic field on mitotic activity A77-11396 SDSBKOV, F. V. Results of exposure of mammalian cell cultures aboard an earth satellite A77-11395 SOTTON, J. B. Pulmonary gas exchange in acute mountain sickness A77-10052 SD7OBOV, P. H. Methods for studying the tolerance of pilots to inflight acceleration A77-11417 SVIBEZBEV, ID. H. Theoretical aspects of the problem of predicting the state of the human organism during space flight A77-11453 SZOSDI, E. Calculating relaxation length from measurement data A77-11309 TAIHBBKOV, H. G. Cellular and molecular aspects of adaptation A77-11430 TARABBIH, S. B. Effect of the 22-day space flight factors on the state of sex glands and reproductive function of rats A77-11U55 TAT/LOB, D. F. Computerized analysis of eye movements during static display visual search [AD-A024100] H77-11680 TAT/LOB, G. B. Joint inflight biomedical experiments performed daring the ASTP spaceflight [IAF PAPER 76-031] A77-10887 TEBBZ, S. L. Determination of faceplate carbon-dioxide concentration levels of self-contained breathing apparatus [PB-252695/2] H77-10796 THOHAS, C. E. Development and evaluation of an ultrasonic imaging system [PB-252561/6] N77-10788 TISBAHIAH. B. A. Some characteristics of the metabolism o£ proteins and ribonucleic acids in the central nervous system of rats in space flight aboard the COSBOS 60S satellite A77-11U32 1-45 1IKBOBIBOV, E. F. PEBSOIAL ADTBOH IBDEI TIKBOBIBOV, E. P. Effect of blood redistribution in the human organism on the perception of body position in space 477-1146(1 IIKHOdOV, 6. P. Pathomorphological changes in rat organs in the case of chronic inhalation of a polyethylsiloxane fluid A77-11460 TIOI07, L. t. The effect of the chronic action of small dosages of ionizing radiation on the excretion of gaseous metabolites among white rats A77-11379 10HLIHSOH, S. ». Halobacterium saccharovorum sp. nov., a carbohydrate-metabolizing, extremely halophilic pactenum A77-10702 TBDHBO, D. A. Drug effects on heart rate and heart rate variability during a prolonged reaction task A77-10274 TSAHEYA, S. P. A sorption method for the reclamation of vater for the personal hygiene of cosmonauts A77-11382 TSVETK07A. I. V. Control of mineral nutrition of higher plants in biological life support systems A77-11356 TUBES, B. L. Influence of auditory fatigue on masked pure-tone thresholds A77-10137 TOBCBABIH07A, V. I. State of vascular regulation and regional bemodynamics in Soyuz-12 and Soyuz-13 crevmembers before and after flight A77-11388 TOBKHEHOV, B. I. (forking capacity of man during stay at high altitudes A77-11364 TURUBI8EB, H. H. Adrenal function in man during exposure to a byperbanc environment for many days /N2-O2, 5 atm/ A77-11410 UEDA, 1. Effects of rapid round trips against time displacement on adrenal cortical-medullary circadian rhythms A77-10065 DSACHE7. V. V. Some responses of man to prolonged centripetal accelerations /+Gz/ of small values A77-11436 OSHiKOV, A. S. Free ammo acids in auman blood plasma during space flights A77-10057 Effect of a 22-day space flight on the metabolism of skeletal muscle tissue in rats A77-11434 Diagnostic significance of free ammo acid content in the blood plasma during dietary protein deficiency in man A77-11441 OSTIOSHIN, B. V. Some responses of man to prolonged centripetal accelerations /+Gz/ of small values A77-11436 VARDEB, A. J. Effects of psychosocial stimuli on plasma renin activity in rats A77-10799 7ANECK, P. The function of the gastrointestinal channel of the rat during shock CMBL-1975-16] H77-10785 7AHKABPEH, C. L. Potential biomedical applications of ion bean technology [HASA-Tfl-X-73512] H77^11655 VAHVBLSEH, F. L. The contraction prolonging action of 9-anthroic acid (AHCA) on the isolated rat diaphragm and the effects of soman on this phenomenon [HB1-1975-25] S77-10779 7ABTBABOH07, B. A. Human tolerance to +GZ accelerations during beating of the body A77-11358 Tolerance to +Gz acceleration of pilots with a tendency toward hypotensive responses under hot climate conditions •~ A77-11435 TASILEVA, T. D. Adaptation of the cardiovascular system to negative stressful acceleration during repeated antiorthostatic exposures A77-11361 State of vascular regulation and regional hemodynamics in Soyuz-12 and Soyuz-13 crevmembers before and after flight A77-11388 VASSODT, P. Influence of the peak pressure and duration of impulse noise (gun fire) on the hearing of the guinea pig [ISL-B-109/75] 1177-11639 Study of metabolic response variation to an acoustic aggression [ISL-H-120/75] H77-11641 7AOGHAH, J. A. Readability of approach charts as a function of visual acuity, luminance, and printing format A77-10051 7EDOLAZOT, A. S. Cardiorespiratory responses of cosmonauts to graded physical iiork after 30- and 63-day flights aboard the orbital base Salyut-4 A77-11452 7EKSHIHA, L. K. Effect of alpha radiation on Chlorella vulgaris at different stages of cellular cycle A77-11422 7EBESOTSKAIA. H. A. Effect of a 22-day space flight on the metabolism of skeletal muscle tissue in rats A77-11434 Protein fractions and their enzyme activity in the rat myocardium after a 22-day space flight A77-11454 VEBIGO, 7. 7. The effect of different regimes of motor activity on the adaptation of man to high altitude A77-11371 Dependence of human body weight loss on space flight duration A77-11415 Theoretical aspects of the problem of predicting the state of the human organism during space flight A77-11453 7IEHTL, J. B. H. Development and evaluation of an ultrasonic imaging system [PB-252561/6] N77-10788 7IKHBO7, N. I. Theoretical aspects of the problem of predicting the state of the human organism during space flight A77-11453 7IL-7I1IABS, I. F. Possibility of prolonged stay in water by means of a 'dry' immersion method A77-11401 7ILIABS, H. 7. Control of mineral nutrition of higher plants in biological life support systems A77-11356 VIZGALIM, A. H. The effect of impact accelerations on the heart and hemodynamics of rats A77-11372 PBHSOHAL 10TBOB IBDBX BOBTB1B, 0. B. VLASOVA, 1. F. Free aaino acids ID human blood plasma during space flights A77-10057 Effect of a 22-day space flight on the netabolisa of skeletal muscle tissue in rats 477-1113Q Diagnostic significance of free au.no acid content in the blood plasma daring dietary protein deficiency in Ban A77-111U1 VODAK, J. Anaerobic threshold and maximal aerobic power for three nodes of exercise A77-11099 VODAK, F. Anaerobic threshold and manual aerobic power for three modes of exercise A77-11099 TOGS, ?. B. Psycho-physiological and physio-chemical assessment of acceleration induced changes in humans positioned in various seatback angle configurations H77-11617 VOIBOVA, I. I. Effect of caloric simulation of the vestibnlar system on body temperature A77-11123 Effect of psychotropic drugs on some indices of the vestibnlar function A77-111128 TOLICEB. L. Effects of head-dovn tilt on fluid and electrolyte balance A77-10058 VOLOZBIB, A. I. State of osseous tissue under conditions of hypokinesia and weightlessness, and the effect of thyrocalcitonin A77-11387 VOBBECKB, H. J. Psycho-physiological and physio-chemical assessment of acceleration induced changes in humans positioned in various seatback angle configurations 877-11617 VOROBEV, A. I. Coronary vessels of the rabbit following single irradiation of the heart area with a dose of 2100 rad A77-11120 VOBOBEV, E. I. The Soyuz-Apollo experimental flight - Preliminary results of medico-biological research carried out during flight of Soyuz-19 A77-11369 Preliminary results of medical studies during the flight of the second expedition of the Salyut t orbital station A77-11150 VOBOSHILOVSKAIi, S. P. State of the labyrinth tonic reflexes of position during the administration of trace elements to rabbits /copper, manganese, and cobalt/ A77-11375 VYSOTSKII, V. G. Diagnostic significance of free ammo acid content in the blood plasma during dietary protein deficiency in man A77-111U1 w HiGHAH, I. B. Principles of biodynamics. Volume 3: Physiological mechanisms in the mammal underlying posture, locomotion, and orientation in space [AD-A023691] N77-11661 BABBBBBBOCK, E. A. Cyclic hypoxic pulmonary vasoconstriction induced by concomitant carbon dioxide changes A77-11098 BALL, P. D. Lack of effect of naloxone on pain perception in humans A77-11175 iABG, B. C. Intracellnlar buffering of heart and skeletal muscles during the onset of hypercapnia A77-11892 iADGH, J. D. Influence of pilot xncapacitation on low speed and hoveriag flight IAD-A023728] N77-11681 IBIGAHD. A. J. Potential bioaedical applications of IOD beam technology (HASA-TU-X-73512] H77-11655 iBLLS, B. B. Experiment design for pilot identification in compensatory tracking tasks 877-10380 BBLSB, K. B. Readability of approach charts as a function of visual acuity, luminance, and printing format A77-10051 BBIIBAH, E. B. Duration of whole-body vibration exposure - Its effect on comfort A77-10311 BICKBAHASIBGBE, B. C. Primitive grain clumps and organic compounds in carbonaceous chondrites A77-11997 BIDIHSKT, J. Pulmonary hypertension A77-12U25 ilJHAHS, H. The function of the gastrointestinal channel of the rat during shock [BBL-1975-16] H77-10785 IILKISS, J. B. Analytical notes - Electrochemical method for early detection and monitoring of coliforms A77-10988 BILLIAHS, B. A. Thermistor holder for skin temperature measurements [ BASA-CASE-ABC-10855-1] 877-10780 BILLI1HS, K. B. The diurnal variation of neutral hepatic fructose 1,6-diphosphatase in partially inbred populations of rats and in outbred populations of Hicrotus montanus A77-10990 RILLIABS, L. G. Dynamic contrast requirements [AD-A023973] N77-11683 ilLLIASS, B. E. An automated miniaturized Haploscope for testing binocular visual function A77-10147 BILHOBB, J. B. Anaerobic threshold and maximal aerobic power for three modes of exercise A77-11099 IIHGBI, C. B. Psychologic and psychophysiologic response to 105 days of social isolation A77-10063 IFITTB, F. P. Intracerebral oxygen and carbon dioxide tensions in the rhesus monkey A77-10055 IOLF, B. J. A solid state digital data recorder for monitoring anthropomorphic dummy impact environments [PB-251036/7] H77-10795 IOLTBDIS, O. L. First results of an investigation of the effects of microwave radiation with low power density on the behavior of rats [BBL-1971-15] H77-10778 HOOD, B. B. Cardiovascular and pulmonary dynamics by quantitative imaging A77-10709 BOODLBI, R. Pulmonary gas exchange in acute mountain sickness A77-10052 IOHTHAH, D. B. SAINT II documentation manual [AD-A021286] N77-11689 I-U7 BYHAH-COP*S»EET, D. PEBSOHAL AOTHOB IHDEI BYHAH-COBBSUEET, D. An automated miniaturized Haploscope for testing binocular visual function A77-10117 IAHAGDCBI, 0. Effects of rapid round trips against time displacement on adrenal cortical-medullary circadian rhythms A77-10065 YAHG, S. H. Studies on the nature of plasma growth horoone A77-10700 YEGOBOV, A. D. Second expedition of the Salyut-U orbital station. Certain results and tasks of medical research [NASA-TT-F-17223] N77-10783 IODNG, K. K. D. Control and trajectory optimization of a robot arm [AD-A023669] N77-11688 ZABD1II, B. B. Genesis of vestibule-vegetative disorders under weightlessness conditions A77-11U66 ZAKHABOTA, I. H. Changes in the monosynaptic H-response of man during altitude decompression A77-11U07 ZAKHBIB, B. B. Plasma angiotensin II levels in hypoxic and hypovolemic stress in unanesthetized rabbits A77-11097 ZALOGOEV, S. H. Possible ways of solving the problem of 'biological compatibility' of crew members in long term space flights A77-11389 ZABOBIHA, K. V. A sorption method for the reclamation of water for the personal hygiene of cosmonauts A77-11382 ZATALISHIHA, B. A. Study of phosphatase activity in the bone tissue and blood secum during 90-day hypokinesia A77-11370 ZEBLIANITSKAIA, E. P. Investigation of the biological properties of type-A Cl. pecfringens released in persons placed in a hermetic chamber A77-11419 ZHBBNA7KOV, A. F. Orthostatic tolerance of cosmonauts after 30- and 63-day flights onboard the orbital base Salyut-U A77-111151 ZICK, G. L. Determination of oxygen tension by measurement of net charge transport A77-12245 ZDBABISBVILI, Z. D. A system of remote utilization of a computer during the processing of biological data A77-12379 NASA-Langley, 1977 1 Report No. NASA SP-7011(16*0 2 Government Accession No 3 Recipient's Catalog Nu 4. Title and Subtitle AEROSPACE MEDICINE AND BIOLOGY A Continuing Bibliography (Supplement 16*0 5 Report Date February 1977 6 Performing Organization Code 7 Author(s) 8 Performing Organization Report No 10 Work Unit No 9. Performing Organization Name and Address National Aeronautics and Space Administration Washington D.C. 20546 11 Contract or Grant No 13 Type of Report and Period Covered 12 Sponsoring Agency Name and Address 14 Sponsoring Agency Code 15 Supplementary Notes 16 Abstract This bibliography lists 275 reports, articles, and other documents introduced into the NASA scientific and technical information system in January 1977- 17 Key Words (Suggested by Author(s)) Aerospace Medicine Bibliographies Biological Effects 18 Distribution Statement Unclassi f ied - Unlimited 19 Security Classif (of this report) Unclassi f ied 20. Security Classif (of this page) Unclassified 21 No of Pages 9*1 22 Price SA.75 HC For sale by the National Technical Information Service, Springfield. Virginia 22161 PUBLIC COLLECTIONS OF NASA DOCUMENTS DOMESTIC NASA distributes its technical documents and bibliographic tools to ten special libraries located in the organizations luted below Each library is prepared to furnish the public such services as reference assistance, intarlibrary loans, photocopy service, and assistance in obtaining copies of NASA documents for retention MASSACHUSETTS Massachusetts Institute of Technology. Cambridge CALIFORNIA University of California, Berkeley COLORADO University of Colorado. Boulder DISTRICT OF COLUMBIA Library of Congress GEORGIA Georgia Institute of Technology. Atlanta ILLINOIS The John Crerar Library. Chicago MISSOURI Linda Hall Library. Kansas City NEW YORK Columbia University. New York PENNSYLVANIA Carnegie Library of Pittsburgh WASHINGTON University of Washington. Seattle NASA publications (those indicated by an "*" following the accession number) are also received by the following public and free libraries: CALIFORNIA Los Angeles Public Library San Oiego Public Library COLORADO Denver Public Library CONNECTICUT Hartford Public Library MARYLAND Enoch Pratt Free Library. Baltimore MASSACHUSETTS Boston Public Library MICHIGAN Detroit Public Library MINNESOTA Minneapolis Public Library MISSOURI Kansas City Public Library St Louis Public Library NEW JERSEY Trenton Public Library NEW YORK Brooklyn Public Library Buffalo and Erie County Public Library Rochester Public Library New York Public Library OHIO Akron Public Library Cincinnati Public Library Cleveland Public Library Dayton Public Library Toledo Public Library OKLAHOMA Oklahoma County Libraries. Oklahoma City TENNESSEE Memphis Public Library TEXAS Dallas Public Library Fort Worth Public Library WASHINGTON Seattle Public Library WISCONSIN Milwaukee Public Library An extensive collection of NASA and NASA-sponsored documents and aerospace publications avail- able to the public for reference purposes is maintained by the American Institute of Aeronautics and Astronautics. Technical Information Service. 750 Third Avenue. New York. New York. 10017 EUROPEAN An extensive collection of NASA and NASA-sponsored publications is maintained by the British Library Lending Division. Boston Spa. Wetherby. Yorkshire, England By virtue of arrangements other than with NASA, the British Library Lending Division also has available many of the ne,n-NASA publications cited in STAR. European requesters may purchase~facsimile copy or microfiche of NASA and NASA-sponsored documents, those identified by both the symbols "#" and "*". from ESRO/ELDO Space Documentation Service. European Space Research Organization, 114. av Charles de Gaulle. 92-Neuilly-sur-Seme. France NATIONAL AERONAUTICS AND SPACE ADMINISTRATION WASHINGTON DC 2O546 OFFICIAL BUSINESS SPECIAL FOURTH CLASS MAIL Book POSTMASTER If Undrliver.ible (Section 158Postal M.inu.i l) Do Not Return NASA CONTINUING BIBLIOGRAPHY SERIES NUMBER NASA SP-7011 NASA SP-7037 NASA SP-7039 NASA SP-7041 NASA SP-7043 NASA SP-7500 TITLE AEROSPACE MEDICINE AND BIOLOGY Aviation medicine, space medicine, and space biology AERONAUTICAL ENGINEERING Engineering, design, and operation of aircraft and aircraft components NASA PATENT ABSTRACTS BIBLIOGRAPHY NASA patents and applications for patent EARTH RESOURCES Remote sensing of earth resources by aircraft and spacecraft ENERGY Energy sources, solar energy, energy conversion, transport, and storage MANAGEMENT Program, contract, and personnel management, and management techniques FREQUENCY Monthly Monthly Semiannually Quarterly Quarterly Annually Details on the availability of these publications may be obtained from: SCIENTIFIC AND TECHNICAL INFORMATION OFFICE N A T I O N A L A E R O N A U T I C S A N D S P A C E A D M I N I S T R A T I O N Washington, D.C. 20546

Aerospace medicine and biology: A continuing bibliography with indexes, supplement 164

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