An X-ray spectral measurement of the quasar 3C 273 with the HEAO-A2 experiment in June/July 1978 is reported. The best power law fit to the photon flux over the range 2-60 keV gives a slope of 1.41 + or - 0.02. However, structure is observed, indicating a slope of 1.52 between 2 keV and 9 keV and a slight flattening between 9 keV and 30 keV. Observations with the same experiment in December 1977 and OSO-8 in June 1976 allows confirmation of 40% intensity variability on the time scale of months, although within limits provided by the poorer statistical quality of the additional data no spectral change is discerned. Absorption from the source is found to be low, with the 1978 data yielding a 90% confidence upper limit to the hydrogen column density of 4.5 x 10 to the 21st power atoms/sq cm
