Biofilms are ubiquitous macro-colonies of bacteria that develop at various
interfaces (solid-liquid, solid-gas or liquid-gas). The formation of biofilms
starts with the attachment of individual bacteria to an interface, where they
proliferate and produce a slimy polymeric matrix - two processes that result in
colony growth and spreading. Recent experiments on the growth of biofilms on
agar substrates under air have shown that for certain bacterial strains, the
production of the extracellular matrix and the resulting osmotic influx of
nutrient-rich water from the agar into the biofilm are more crucial for the
spreading behaviour of a biofilm than the motility of individual bacteria. We
present a model which describes the biofilm evolution and the advancing biofilm
edge for this spreading mechanism. The model is based on a gradient dynamics
formulation for thin films of biologically passive liquid mixtures and
suspensions, supplemented by bioactive processes which play a decisive role in
the osmotic spreading of biofilms. It explicitly includes the wetting
properties of the biofilm on the agar substrate via a disjoining pressure and
can therefore give insight into the interplay between passive surface forces
and bioactive growth processes
