We assess the impact of cell cycle noise on gene circuit dynamics. For
bistable genetic switches and excitable circuits, we find that transitions
between metastable states most likely occur just after cell division and that
this concentration effect intensifies in the presence of transcriptional delay.
We explain this concentration effect with a 3-states stochastic model. For
genetic oscillators, we quantify the temporal correlations between daughter
cells induced by cell division. Temporal correlations must be captured properly
in order to accurately quantify noise sources within gene networks.Comment: 15 pages, 8 figure
