The present issue is the first of of a two-volume review devoted to gamma-ray
astronomy above 100 MeV which has witnessed considerable progress over the last
20 years. The motivations for research in this area are explained, the
follow-on articles of these two thematic issues are introduced and a brief
history of the field is given.Comment: 15 pages, 6 figures. Introduction to a two-volume topical issue on
Gamma-ray Astronomy above 100 MeV coordinated by the author