We present a coarse-graining strategy that we test for aqueous mixtures. The
method uses pair-wise cumulative coordination as a target function within an
iterative Boltzmann inversion (IBI) like protocol. We name this method
coordination iterative Boltzmann inversion (CβIBI). While the
underlying coarse-grained model is still structure based and, thus, preserves
pair-wise solution structure, our method also reproduces solvation
thermodynamics of binary and/or ternary mixtures. Additionally, we observe much
faster convergence within CβIBI compared to IBI. To validate the
robustness, we apply CβIBI to study test cases of solvation
thermodynamics of aqueous urea and a triglycine solvation in aqueous urea