The effect of alloxan diabetes mellitus on experimental cholesterol arteriosclerosis in the rabbit.

Abstract

As social and medical progress have gradually emancipated mankind from many of the more acute and fatal diseases, so have the diseases associated with old and middle age come into prominence. Among these latter is arteriosclerosis - a disease which, with its sequelae, has assumed major importance as a cause of death and physical incapacity. Study of' the disease has yielded an immense amount of information but, up to the present, little understanding of its fundamental properties, and nothing of value for its prevention or cure. Any study which may elucidate the pathogenesis of arteriosclerosis is, therefore, of value; and it is to this end that the present experiment was designed.[...