INDISIM-YEAST, an individual-based simulator, models the evolution of a yeast population by setting
up rules of behaviour for each individual cell according to their own biological rules and characteristics. It
takes into account the uptake, metabolism, budding reproduction and viability of the yeast cells, over a
period of time in the bulk of a liquid medium, occupying a three dimensional closed spatial grid with two
kinds of particles (glucose and ethanol). Each microorganism is characterized by its biomass, genealogical
age, states in the budding cellular reproduction cycle and position in the space among others. Simulations
are carried out for population properties (global properties), as well as for those properties that pertain to
individual yeast cells (microscopic properties). The results of the simulations are in good qualitative
agreement with established experimental trends.Peer Reviewe
