从南方红豆杉皮层分离到一株瘤座孢，其发酵提取物经TlC、HPlC分析以及抗瘤和促微管聚合活性测定，结果提示可能存在紫杉醇或紫杉醇类的活性物质.Strain TF 5, isolated from the inner bark of the Chinese Yew, Taxus mairei , grew rapidly in PDA.The colony reached more than 9 cm in diameter after 7 days incubation.The stromata, dark brown, rounded and irregular shape, appeares on the colony after about 20 days.The conidioiphore is pale yellow and has 2￣4 levels of branch.The spore is single, hyaline, dry, and oval to pyriform.The base end of the spore is truncate rounded and has an obvious scar.Some spores have a short sericate remains.It was identified as one kind of Tubercularia sp .by comparing with authentic taxol through TLC and HPLC, showing this strain to produce taxol or its analogue in mycelial culture.The products in PDA fermentation broth (25 ℃, 140r/min, 15days) approximately reached 185.4 μg/L.The products has toxicity to cancer cell lines KB and P388, while induces tubulin polymerization in vitro , similar to taxol
