半纤维素是自然界中最丰富的可再生资源之一,将半纤维素降解为单糖并转化为燃料或化学品一直是科学界研究的热点。半纤维素是由木糖基主链以及α-葡萄糖醛酸等侧链共同组成的异质多聚体。α-葡萄糖醛酸酶是半纤维素完全降解过程中的关键酶之一,能够水解4-O-甲基葡萄糖醛酸与木糖之间的α-1,2-糖苷键。本文综述了α-葡萄糖醛酸酶的分类、催化机制及晶体结构、酶学性质和基因克隆表达等方面的研究进展,同时对该研究进行了展望。Hemicellulose is one of the most abundant renewable resources in nature.The bioconversion of hemicellulose into biofuels or chemicals is a research hotspot in the world.Hemicellulose consists of a backbone of xylan residues and some branches like glucuronic acid.α-Glucuronidase, which is capable to hydrolysis the α-1,2-glycosidic bond between xylan and glucuronic acid, is one of the key enzyme to degrade hemicellulose completely.The recent research progresses on catalysis mechanism, structure, charaterization, and gene cloning of α-glucuronidase are summarized in this paper.国家自然科学基金(31170067;21303142); 国家重点基础研究发展计划(973计划;2010CB732201); 福建省自然科学基金(2012J05029); 农业部“引进国际先进农业科学技术”项目(2013-Z70
