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Investigation of the Association Between Bovine Serum Albumin(BSA) and Aluminum Tetrasulfonated Phthalocyanine(AlS4 Pc) by Fluorescence Anisotropy

Abstract

Fluorescence anisotropy was employed for the investigation of the association between AlS 4Pc and BSA.The average binding number of AlS 4Pc to BSA was calculated and the constants of association reaction occurring in the medium of pH 7 0 were shown.The results revealed that the interaction between AlS 4Pc and BSA was strong, which implied that AlS 4Pc may be stored and transferred by serum albumin.The merits of the method used were also pointed out.国家自然科学基金!(批准号:29775021)资

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