恶性肿瘤的发病率在世界范围内逐渐增高，而肿瘤的发生与一些肿瘤相关基因的改变相关，即癌基因与抑癌基因之间的平衡被打破造成的，非正常的生活方式、各种污染、激素变化、辐射、药物及基因等因素也是其诱因。 肿瘤坏死因子α诱导蛋白8(tumornecrosisfactorαinducedprotein-8,TNFAIP8)是转录因子NF-κB可诱导的抗凋亡，致癌分子，分子量为21kD的胞浆蛋白。TNFAIP8在肾癌及乳腺癌中高表达，过表达的TNFAIP8可导致乳腺癌、肺癌、肾细胞癌和食管鳞状细胞癌的进展，因其在细胞凋亡信号转导、肿瘤发生、侵袭及转移过程中具有重要调控作用而逐渐成为研究的热点。 为了...Irregular lifestyles, pollution, radiation, hormone changes, drugs, genes and other factors are causing the incidencement of growing malignant tumors all over the world, while cancers are due to the changes of tumor-related genes, that is breaking the balance between oncogenes and tumor suppressor genes. Tumor necrosis factor alpha induced protein 8 (tumor necrosis factor- α inducedprotein-8,...学位：理学硕士院系专业：医学院_药理学学号：2452011115339
