脊椎动物中免疫系统主要由天然免疫与适应性免疫两部分组成。鱼类作为最低等的脊椎动物，虽然在进化中获得了适应性免疫，由于鱼类的适应性免疫的产生受到多重因素的影响。在抵抗外界病原入侵的过程中，鱼类的天然免疫系统仍然具有至关重要的作用。本研究以赤点石斑鱼与大黄鱼为研究对象，对赤点石斑鱼的天然免疫因子凝集素、MHCIIB与ICLP，大黄鱼的识别因子肽聚糖识别蛋白（peptidoglycanrecognitionprotein，PGRP）与巨噬细胞移动抑制因子（MacrophageMigrationInhibitoryFactor，MIF）进行了初步研究。报告内容如下： 1.凝集素(lectin)在脊椎...The immunology system of vertebrate is comprised of innate and adaptive defense mechanisms. As a kind of primitive vertebrates, fish obtained the adaptive immunity in ancient evolutionary history Meanwhile, this specific immune defense in fish has more constraints than endothermic vertebrates when focus on their temperature-dependent, limited antibody repertories, affinity maturation and relativel...学位：博士后院系专业：海洋与环境学院海洋学系_水生生物学学号：BH1700018
