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Development of Analytical Method of Neomycin Residue in Water Samples and Its Application on the Analysis of Animal Products

Abstract

新霉素(Neomycin)是一类抗菌活力强、作用范围广,用于治疗畜禽类疾病的氨基糖苷类抗生素。新霉素的广泛应用引发了动物食品内日益严重的残留问题,因此,新霉素的残留分析和控制显得愈发重要。本论文以阴离子交换色谱为分离方法,结合脉冲安培检测法分析水中新霉素残留,并在此基础上发展生物样品的预处理方法,将该方法成功运用于牛奶和血清样品中新霉素残留的灵敏、快速检测。研究的主要内容和结果如下: 1)水样中新霉素分析方法的建立 运用阴离子交换色谱和脉冲安培检测器,建立简单、快速、可靠的新霉素残留分析方法。考察流动相浓度和pH对色谱分离和检测的影响,确定色谱分离的最佳流动相条件为10mmol/LNaOH...Neomycin is a broad spectrum, efficiently bactericidal aminoglycoside antibiotic, which is widely used in the treatment of bacterial infections and animal diseases. The use of neomycin on a large scale as a therapeutic agent gives rise to drug residues in edible products of animals, which can adversely affect the public health and environmental safety. Therefore, residue analysis plays an importan...学位:理学硕士院系专业:海洋与环境学院环境科学与工程系_环境科学学号:20043406

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