独特的海洋环境中,存在着具有药用价值的新颖结构化合物。本研究选取了一种广泛分布的经济藻类—自养小球藻(Chlorellaautotrophica)为研究对象,优化提取其硫酸多糖,对所得粗产物分离纯化流程进行了研究。通过化学方法阐明了其化学组成及结构,并对其抑菌活性做了初步探讨。自养小球藻属于绿藻门(Chlorophyta)绿球藻目(Chlorococcales)卵囊藻科(Oocysteceae)小球藻属(Chlorella),是一种广泛分布的海洋微藻。在超声辅助提取法中,我们选用了0.01mol/L的HCl、纯水及4%NaOH为提取介质,在超声破碎10min,重复2次,超声功率300W,频率2...There are novel structure compounds in unique ocean environment that would contribute to new medicines. Chlorella autotrophica, a wide distributed economic alga, was studied in our research, we optimized the extraction of sulfated polysaccharides, explore the process of separation and purification, illustrate the composition and structure and by chemical methods and give a primary discuss about th...学位:理学博士院系专业:海洋与环境学院海洋学系_海洋化学学号:B20042700