海洋生态系统的复杂性使海洋生物面临低氧、酸化、环境污染物等多重环境胁迫,特别是沿海海域的海洋生物。研究表明低氧、酸化及环境雌激素EE2均能影响生物体的生长、发育、繁殖及基因表达等。Hepcidin是一类与防御素类似的富含半胱氨酸的抗菌肽,除具有抗菌功能外还参与机体铁代谢;贫血、缺氧、致炎物质以及细胞因子等均会影响其表达。本论文在实验室前期研究分离获得的海水青鳉(Oryziasmelastigma)hepcidin两种变体基因OM-hep1和OM-hep2以及黑鲷(Acanthopagrusschlegelii)hepcidin2(AS-hep2)基因的基础上,研究低氧对黑鲷hepcidin2及...Marine organisms are affected by hypoxia, acidification and environment pollutants in the complicated ocean ecosystem, especially in the coastal area. Some researches demonstrate that hypoxia, acidification and environmental estrogen EE2 can affect the growth, development, reproduction and gene expression of marine organisms. Hepcidin is a class of cysteine-rich antimicrobial peptides similar to d...学位:理学硕士院系专业:环境与生态学院_环境科学学号:2262011115145