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The effects in glutathione metabolism in mussel (Perna viridis) with its exposure to bromobisphenol A (TBBPA)

Abstract

近年来,四溴双酚A(TBBPA)作为一种溴代阻燃剂在世界范围内被广泛应用,但人们对它的认识却十分有限。有限的研究显示,其对环境具有潜在危害性。本文以翡翠贻贝(PernaViridis)为实验动物初步探讨了TBBPA的毒理学效应,检测了暴露于1µg/L(低浓度组)、10µg/L(中浓度组)和100µg/L(高浓度组)TBBPA1、4、7、14、21、28d后,翡翠贻贝消化腺内还原型谷胱甘肽(GSH)含量的变化、氧化型谷胱甘肽(GSSG)含量的变化,以及谷胱甘肽代谢相关酶——谷胱甘肽转硫酶(GSTs)、α型谷胱甘肽转硫酶(GST-α)、π型谷胱甘肽转硫酶(GST...In recent years, Tetrabromobisphenol A (TBBPA) is widely used flame- retardant in the world; a few researches show that TBBPA is potentially harmful to the environment. Therefore this study was performed to evaluate the possible toxic effects of TBBPA on mussel (Perna Viridis). In this work, mussels were exposed to TBBPA with the concentration 1 μ g / L, 10 μ g / L and 100 μ g / L for 1, 4, 7, 14,...学位:理学硕士院系专业:海洋与环境学院环境科学与工程系_环境科学学号:2122005130221

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