研究目的：探讨肿瘤坏死因子-α（TumorNecrosisFactor-α，TNF-α）刺激后胃黏膜上皮细胞GES-1细胞间粘附分子1(Intercellularadhesionmolecule1，ICAM1)、血管细胞黏附分子1（Vascularcelladhesionmolecule1，VCAM1）表达变化，以及TFF1（Trefoilfactorfamily1，TFF1）过表达对GES-1细胞中TNF-α诱导的ICAM1、VCAM1表达的影响。 研究方法：以永生化的胃黏膜上皮细胞株GES-1为研究对象，采用不同浓度的人重组TNF-α刺激该细胞株，RT-PCR和WesternBlot...Objective: To investigate TNF-α induced expression of intercellular adhesion molecule 1 (ICAM1),vascular cell adhesion molecule1(VCAM1) in human gastric epithelial cell GES-1, and to investigate the effect of trefoil factor 1 on the expression of ICAM1 and VCAM1 induced by TNF-α. Methods: Human gastric mucosal epithelial cell GES-1 were cultured in vitro. After incubated with different concentrat...学位：理学硕士院系专业：医学院临床医学系_内科学学号：2452007115257
