瘦素（leptin）是由白色脂肪组织分泌的一种重要的摄食调控和能量代谢调节因子，不仅参与维持能量代谢的平衡，对动物生长发育、繁殖等生理过程也起着重要的作用。与哺乳动物中的研究相比，leptin在禽类中的研究相对滞后。本文以金定鸭为研究对象，克隆了家鸭leptin受体（leptinreceptor，LEPR）2种亚型基因，同时进行了组织器官定位分析；进行了外源leptin对禁食后恢复期家鸭受损卵巢恢复调控的初步探索及可能机制研究。取得了如下结果：（1）以家鸭卵巢cDNA为模板，利用反转录PCR（RT-PCR）和cDNA末端快速扩增（RACE）技术首次克隆了家鸭LEPR两种选择性剪切体LEPR-a...Leptin is a protein secreted primarily by white adipose tissue, in addition to its effects on food intake and energy expenditure balance, leptin has been implicated as a mediator of diverse physiological processes, such as growth, development and reproduction. There are numerous studies about leptin in mammals, however, little is known about biological role of leptin in avian. In the present study...学位：理学博士院系专业：生命科学学院生物学系_动物学学号：2012005140311
