嗜水气单胞菌(Aeromonashydrophila)是危害大黄鱼（Pseudoscianacrocea）养殖的重要病原。本论文研究了大黄鱼内源性凋亡途径在细菌感染中的作用，为揭示内源性凋亡途径在抗细菌感染中的作用机制奠定了基础，也为进一步探索大黄鱼病害防治的新途径提供科学依据。通过简并引物、3’和5’RACE获得了大黄鱼内源性凋亡途径中的三个重要基因：cytochromec(Lyccytc)、caspase-9(Lyccasp9)和caspase-3(Lyccasp3)的全长cDNA。Lyccytc编码104aa，其基因组含有2个外显子，1个内含子。Lyccasp9编码437aa，包括三个结...A. hydrophilais is one of the devastating pathogens in the farming of large yellow croaker. This study aimed at the mechanisms of intrinsic apoptotic pathway in large yellow croaker against the infection of A. hydrophilais. These works would be helpful for the enhancement of the ability against the diseases of large yellow croaker. In this investigation, we obtained three important genes, cytochro...学位：理学博士院系专业：生命科学学院生物学系_生物化学与分子生物学学号：2012005140315
