unknown

Effects of inhibitors on Mushroom Tyrosinase and Their Antimicrobial Activity

Abstract

酪氨酸酶(EC.1.14.18.1)是结构复杂的多亚基的含铜氧化还原酶,具有单酚酶活性和二酚酶活性,是生物体合成黑色素的限速酶,广泛存在于微生物、动植物及人体中。其抑制剂广泛应用于化妆品美白、果蔬保鲜及杀虫等方面。本论文从两大方面研究了抑制剂对酪氨酸酶的抑制活性和抗菌效应。第一部分选择了肉桂酸及其衍生物、肉桂醛及其衍生物、肉桂酸甲酯、曲酸和氰基化合物等五大类抑制剂,研究了它们对酪氨酸酶的抑制机理;第二部分以大肠杆菌、枯草芽孢杆菌、金黄色葡萄球菌和白色假丝酵母菌作为试验菌种,研究抑制剂的抗菌效应。 1)肉桂酸、4-羟基肉桂酸和4-甲氧基肉桂酸对酪氨酸酶具有单酚酶和二酚酶的抑制活性,实验结果表明...Tyrosinase (EC 1.14.18.1) is a copper-containing enzyme, which is of the activity of monophenolase and diphenolase, is widely distributed in microorganisms, animals and plants. Its inhibitors can be used widely in many fields including whitening agents, keeping fruits and vegetables fresh, insecticides. Our research in the present paper is composed of two parts. In the first part, we chose cinnami...学位:理学硕士院系专业:生命科学学院生物化学与生物技术系_生物化学与分子生物学学号:20042609

    Similar works