广州管圆线虫(Angiostrongyluscantonensis)幼虫可入侵人体并停留在中枢神经系统,引起嗜酸粒细胞增多性脑膜脑炎。广州管圆线虫病作为一种新发的传染病正受到越来越多的重视,其许多生物学特性尤其是分子生物学方面的特性还未被认知。因此,寻找广州管圆线虫与宿主相互作用的抗原或过敏原及其功能蛋白,对广州管圆线虫病的预防和治疗有重要意义。本研究从GenBank下载1277条广州管圆线虫的表达序列标签(EST),用BlastX比对分析,并用SignalPV3.0预测潜在的抗原或过敏原相关蛋白N端是否具有分泌信号肽或信号锚定肽。结果显示,得分值大于80有695条,其中14条与广州管圆线虫一...The infective third-stage larve(L3) of Angiostrongylus cantonensis can orally infect human and are carried in the blood to the central nervous systerm, which caused eosinophilic meningitis. Now Angiostrongyliasis has attracted more and more attention. We still know very little about the Angiostrongylus cantonensis especially in the field of mocular biology. Therefore, finding out new antigen and f...学位:理学硕士院系专业:生命科学学院生物学系_动物学学号:2172008115251