Preparation and Characterization of the HA/MWNTs and HA/TiO2 Nanotubes Composite Biomaterials

Abstract

羟基磷灰石(HA)是人体骨骼和牙齿的最主要无机成分,人工合成的HA具有良好的生物相容性和生物活性,但HA脆性大、强度低,抗折强度和断裂韧性指标均低于人工致密骨的特性,限制了它在临床的实际应用。医用金属钛表面涂覆HA可结合金属材料的良好力学性能和HA良好生物性能,已被广泛地用作人体硬组织替代材料。然而,HA与钛基底热膨胀系数失配造成的残余应力,降低了涂层与基底之间的结合力,临床应用中常出现涂层脱落或植入体松动现象。二氧化钛纳米管具有良好的生物活性、抗腐蚀性及耐磨损性,因此,发展HA/二氧化钛纳米管复合增强体,可望起到增韧补强作用,提高HA涂层的力学性能,具有重要的临床应用价值。磷酸钙骨水泥(CP...Hydroxyapatite (Ca10(PO4)6(OH)2, HA) is the main inorganic component in natural bone and tooth. The synthetic form of HA has good biocompatibility and bioactivity, unfortunately, its mechanical properties including brittleness, low strength, flexural strength and fracture toughness all are lower than that of natural bone, which inhibits its clinical applications. Conducting HA coatings on biomedic...学位:理学硕士院系专业:化学化工学院化学系_物理化学(含化学物理)学号:2052006115200

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