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Adhesion and application research on green mussel (Perna viridis) adhesive foot protein 1 (Pvfp-1)

Abstract

海洋贻贝粘附蛋白(marinemusseladhesiveproteins,MAPs)具有极强的粘附性、韧性和防水性,这使得贻贝粘附蛋白不仅在海水设备的防水、抗菌和密封等水下作业方面有着较广泛的应用前景,其良好的生物相容性更使其在生物医学领域(如粘接断裂骨骼、粘合软组织、改善材料表面生物活性等)也有重要的潜在应用价值。由于贻贝足蛋白Mfp-1(musselfootprotein1)具有的粘附性能被认为是源自其含有DOPA的十肽重复序列,而翡翠贻贝足蛋白Pvfp-1(Pernaviridisfootprotein1)的十肽重复序列并不含有DOPA。因此,本文根据Pvfp-1的结构特点,应用基因工...Marine mussel adhesive proteins (MAPs) have properties such as strong adhesion, intensity, and moisture-resistance. These characteristics make MAPs attracted increasing attention for its potential application in underwater sealants and adhesives. Since MAPs are biocompatibale and biodegradable, they have considerable importance in biomedical engineering such as being applied as bioadhesive. Mfp-1 ...学位:理学博士院系专业:材料学院材料科学与工程系_高分子化学与物理学号:2072008015000

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