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Separation and purification of astaxanthin from Phaffia rhodozyma and the immunomechanism of astaxanthin

Abstract

虾青素是一种具有极强抗氧化和抗衰老活性的类胡萝卜素,被誉为“超级维生素E”,在医药、保健和化妆品等方面有着广泛的应用价值。为了满足日益增加的市场需求,急需进一步降低虾青素的生产成本,目前市售虾青素主要来源是雨生红球藻,而对于红发夫酵母来源虾青素的分离提纯却鲜有报道;另一方面,虽然虾青素强大的生理功能已逐渐被人所知,但对其免疫功能及其作用机理尚未有深入的研究报道,为使虾青素在人类健康方面更好地发挥作用,对其免疫机理的研究也是非常必要的。 本文首先对红发夫酵母虾青素的分离纯化进行研究。采用高压匀浆破碎法破碎红发夫酵母细胞,考察不同破碎压力、破碎次数和处理量对细胞破壁及虾青素萃取率的影响;结果表明...Astaxanthin, one kind of high-effective antioxidative and antiaging carotenoid, is well-known as "super vitamin E"and widely utilized in pharmaceuticals, cosmetics and health care fields. In order to meet the increasing market demand, it is very urgent to reduce the cost of astaxanthin production. Haematococcus pluvialis is the main soure of commercial astaxanthin currently. However, no special at...学位:工学硕士院系专业:化学化工学院_化学工程学号:2062010115143

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