背景:心源性脑栓塞(cardiogeniccerebralembolism,CCE)是缺血性脑卒中的一个重要的亚型,是由心内膜和瓣膜产生的栓子进入颅内动脉引起的血管腔急性闭塞。CCE的临床特点是起病急,迅速达到高峰,神经功能损害重,致残率和死亡率高。另外不容忽视的是心衰、各种心律失常和肺部感染等并发症多。CCE的出血转化率很高,出血转化又可进一步加重病情,延长患者的住院和康复时间,且更容易出现各种并发症,导致致残率和死亡率的增加。国内尚没有诊疗指南规范指导心源性脑栓塞的急性期治疗。 目的:比较由非瓣膜性房颤引起的非大面积心源性脑栓塞的急性期抗栓治疗中的抗凝药及抗血小板聚集药的疗效和安全性。 ...Background:Cardiac cerebral embolism (CCE) is an important kind of ischaemic stroke, which is caused by the emboli coming from the endocardium and valve. The Embolus can block the arteries in the brain. Cardiogenic cerebral embolism is characterized by the rapid clinical onset, the heavy neurological damage, a quickly reached peak and high morbidity and mortality. The complications of cardiogenic ...学位:医学硕士院系专业:医学院_内科学学号:2452011115334