This thesis explores a broad range of topics in the foundations of relativity and quantum information theory. The first and main topic of this thesis is on relativistic quantum information theory. Here we construct a reformulation of quantum information, which is consistent with relativity theory. We will see that by providing a rigorous formulation starting with the field equations for a massive fermion and a photon we can construct a theory for relativistic quantum information. In particular we provide a measurement formalism, a transport equation which describes the unitary evolution of a state through spacetime as well as how to extend this to multipartite systems. The second topic concerns the nature of time, duration and clocks in current physical theories and in particular for Newtonian mechanics. We analyse the relationship between the readings of clocks in Newtonian mechanics with absolute time. We will see that in order to answer this question we must provide not only a model for a clock but also solve what is referred to as Newton’s Scholium problem. We then compare this with other dynamical theories in particular quantum mechanics and general relativity where the treatment of time is quite different from Newtonian mechanics. The final topic is rather different from the first two. In this chapter we investigate a range of methods to perform tomography in a solid-state qubit device, for which a priori initialization and measurement of the qubit is restricted to a single basis of the Bloch sphere. We explore and compare several methods to acquire precise descriptions of additional states and measurements, quantifying both stochastic and systematic errors, ultimately leading to a tomographically-complete set that can be subsequently used in process tomography. We focus in detail on the example of a spin qubit formed by the singlet-triplet subspace of two electron spins in a GaAs double quantum dot, although our approach is quite general