<i>N</i>-Hydroxyphthalimidyl diazoacetate (NHPI-DA): a modular methylene linchpin for the C–H alkylation of indoles

Abstract

The insertion of conventional diazocompounds into indoles are still limited by the custom carbene precursors, catalysts and manipulation of the products required. Herein, we address these shortcomings with a redox-active carbene precursor (NHPI-DA).</p