New geological and morpho-structural surveys are integrated with seismological and seismic reflection data in order to define the active and potentially seismogenic sources of the Lunigiana and Garfagnana extensional basins (Tuscany, Northern Italy). The seismogenic role of the E-W-striking transfer fault between the Lunigiana and Garfagnana basins, located at the northern termination of the Apuane metamorphic core, and its possible association with a number of historical earthquakes are also discussed