Nase moznosti rozsireni laboratornich vysetreni muzskeho faktoru neplodnosti.

Abstract

The thesis evaluates theoretical and practical possibilities of laboratory examinations of the male infertility factor in a center of assised reproduction. Besides urological and genetic examinations the author tried to introduce, verify and evaluate the contribution of the hormonal profile of subfertile men. The spectrum of examinations in the andrological laboratory was enlarged by examination of biochemical parameters of seminal plasma and by microbiological examination. Among the biochemical parameters of seminal plasma, the highest importance (p=0,05) is to be seen in the examination of alpha-glucosidase, reflecting the function of epididymis. Together with the determination of fructose, a marker of seminal vesicles function, these examinations help to precise the diagnosis of obstructive azoospermia. Microbiological tests confirmed a negative influence of sperm infection by pathogens on the result of a therapeutic cycle of in vitro fertilization and embryotransfer and on the fertility of men. The question of the role of chlamydia infection in male infertility remains, in spite of developed diagnostic possibilities, solved only in part.Available from STL Prague, CZ / NTK - National Technical LibrarySIGLECZCzech Republi