TRANSPORT OF THE SINGLE-VALENT CATIONS THROUGH THE MEMBRANE OF ERYTHROCYTES OF THE FROGS RANA TEMPORARIA AND RANA RIDIBUNDA

Abstract

The object of investigation: the insulated erythrocytes of the frogs. The work is aimed at studying the mechanism of motion of the ions of natrium and kalium through the membrane of erythrocytes of the frogs and factors of regulation of the cation-transporting system activity. A comparative study of the cations transport into erythrocytes of the two species of the frogs has been performed. It has been shown, that the ions of kalium enter the erythrocytes through the Na-K-pump, K-Cl-contransporter and the residual component. The ions of natrium are being transported into the cells only by the way of diffusion, the Na/H exchanger is being activated in the hypertonic medium. The influence of temperature on the cation-transporting systems activity in the frogs' erythrocytes Rana temporaria has been studied. It has been shown, that the support of the ion homeostasis of erythrocytes of the animals, adapted during the long time to the low temperatures, is being provided due to the preservation of the natrium pump high activity and the reduction of the value of the cation streams passive. For the first time it has been established, that catecholamines and blockators phosphodieesterases activate the Na-K-pump in the erythrocytes of the frogs Rana temporaria; in the performance of a signal, the system of beta -adrenoreceptors take part. The results widen the theoretic presentations about the mechanisms of functioning and regulation of the systems of the ion transport through the cells membranes and can be used in studying the pathological processes, connected with the variations of the work of the particular iontransporting systemsAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio