THE MONOCLONAL ANTIBODIES TO ANTIGENES OF THE MEMBRANES OF THE FAT GLOBULES OF MOTHER MILK AND ITS USE WITH THE MORPHOLOGICAL INVESTIGATION OF THE MAN'S TUMORS

Abstract

The object of investigation: the woman's milk, the cultural fluid of the hybridome and ascitic fluid of mice, the normal and tumor tissues of the man. For the high-cleaned antigenes of the membranes of the mammary glans cells AG3 and AG4, the monoclonal antibodies IKO21, 26, 29 and IKO22, 25 have been obtained. It has been shown, that the monoclonal antibodies IKO25 interacts specifically with the epithelium and the tumors of the epithelial origin can be used for studying the processes of the malignant transformation of the epithelium, for the search of the micrometastases of the antigen-containing tumors in the lymphonods and marrow, the specifying differential diagnostics of the tumors of the epithelial and not epithelial genesisAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio