Resorbierbare Glaskeramik mit kontrolliertem Aufloesungsvermoegen Abschlussbericht

Abstract

For the development of rapidly resorbable, long-term stable bioactive glass ceramics as new implant materials, the system CaO-P_2O_5-K_2O-Na_2O-MgO(-SiO_2) has been reinvestigated. Starting from CaNaPO_4, glassy-crystalline materials of higher solubility than hydroxylapatite and #alpha#-tricalcit phosphate have been obtained. As main phases Ca_4MgNa_5(PO_4)_5, MgKPO_4 and Ca_2KNa(PO_4)_2 have been isolated and characterized. Solubility rates of the materials were determined by screening tests. Biological compatibility was tested in vitro as well as in vivo experiments. (WEN)SIGLEAvailable from TIB Hannover: F96B441+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman