Let R0 be any domain, let R=R0[U1,...,Us]/I, where U1,...,Us are indeterminates of some positive degrees, and I⊂R0[U1,...,Us] is a homogeneous ideal. The main theorem in this paper is states that all the associated primes of H:=HR+s(R) contain a certain non-zero ideal c(I) of R0 called the
``content'' of I. It follows that the support of H is simply V(\content(I)R + R_+) (Corollary 1.8) and, in particular, H vanishes if and only if c(I) is the unit ideal. These results raise the question of whether local cohomology modules have finitely many minimal associated primes-- this paper provides further evidence in favour of such a result. Finally, we give a very short proof of a weak version of the monomial conjecture based on these results