Among U.S. states, Hawaii stands out for it's very high rate of colonization by non-indigenous species. Hawaii's need for prevention and management of invasive species are arguably greater than for the rest of the United States because both tourism and agriculture require a relatively pest-free environment to flourish. In addition, Hawaii's highly endemic biodiversity, several spectacular national parks, and about one-third of all federally listed endangered species are also at risk and threatened primarily by current and future invasions. This paper examines Hawaii's federal and state quarantine entities and procedures. Comparisons are made to quarantine developments in Australia and New Zealand