Understanding growth hormone sensitivity and responsiveness: factors affecting IGF-1 response to growth hormone

Abstract

In endocrinology dynamic testing forms an essential part of investigation. To assess the central capacity of the GH-lGF-1 axis there is extensive experience in paediatric and adult populations of numerous physiological and pharmacological tests. However tests to assess the peripheral capacity of the GH-IGF-1 axis beyond a simple baseline lGF-1 level are limited to the IGF-1 generation test (IGFGT).EThOS - Electronic Theses Online ServiceGBUnited Kingdo