The biosynthesis and membrane integration of P2X2 at the endoplasmic reticulum

Abstract

A crucial step in the biosynthesis of membrane proteins is their incorporation into the hydrophobic environment of the lipid bilayer. In eukaryotic cells this event occurs largely in concert with translation on ribosomes bound to the membrane of the endoplasmic reticulum (ER) at a site termed the ER translocon.EThOS - Electronic Theses Online ServiceGBUnited Kingdo