Homolog pairing during meiosis : dyneins on the move

Abstract

Meiosis is a specialized form of cell division that generates haploid gametes from diploid cells. This is achieved by having 1 round of DNA replication followed by 2 rounds of nuclear division. A unique aspect of meiosis is that homologous chromosomes undergo recombination that can result in formation of chiasmata. This is essential for bi-orientation of bivalents on the meiosis I spindle. But how a chromosome pairs with its homolog and engages in recombination is poorly understood