In this thesis, we focus on mathematical optimization models and algorithms for solving routing and logistic problems. The first contribution regards a path and mission planning problem, called Carrier-Vehicle Traveling Salesman Problem (CVTSP), for a system of heterogeneous vehicles. A Mixed-Integer Second Order Conic Programming (MISOCP) model and a Benders-like enumeration algorithm are presented for solving CVTSP. The second work concerns a class of routing problems, referred to as Interceptor Vehicle Routing Problems (IVRPs). They generalize VRPs in the sense that target points are allowed to move from their initial location according to a known motion. We present a novel MISOCP formulation and a Branch-and-Price algorithm based on a Lagrangian Relaxation of the vehicle-assignment constraints. Other two contributions focus on waste flow management problems: the former considers a deterministic setting in which a Mixed-Integer Linear Programming (MILP) formulation is used as a Decision Support System for a real-world waste operator, whereas the latter deals with the uncertainty of the waste generation amounts by means of Two-Stage Multiperiod Stochastic Mixed-Integer Programming formulations. Finally, we give an overview on the optimization challenges arising in electric car-sharing systems, both at strategic and tactical planning level
